Ghent University Academic Bibliography

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Your filters: cql: author="Heirman, Carlo" or (type any "bookEditor issueEditor" and editor="Heirman, Carlo")

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Intranodal administration of mRNA encoding nucleoprotein provides cross-strain immunity against influenza in mice

Patrick Tjok Joe, Ioanna Christopoulou (UGent) , Lien Van Hoecke (UGent) , Bert Schepens (UGent) , Tine Ysenbaert (UGent) , Carlo Heirman, Kris Thielemans, Xavier Saelens (UGent) and Joeri Aerts

(2019) JOURNAL OF TRANSLATIONAL MEDICINE. 17.
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- Journal Article
- A1
Vegf-A mRNA transfection as a novel approach to improve mouse and human islet graft revascularisation

Willem Staels (UGent) , Yannick Verdonck, Yves Heremans, Gunter Leuckx, Sofie De Groef, Carlo Heirman, Eelco de Koning, Conny Gysemans, Kris Thielemans, Luc Baeyens, et al.

(2018) DIABETOLOGIA. 61(8). p.1804-1810
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Dendritic cell targeting mRNA lipopolyplexes combine strong antitumor T-cell immunity with improved inflammatory safety

Kevin Van der Jeught, Stefaan De Koker, Lukasz Bialkowski, Carlo Heirman, Patrick Tjok Joe, Federico Perche, Sarah Maenhout, Sanne Bevers, Katrijn Broos, Kim Deswarte (UGent) , et al.

(2018) ACS NANO. 12(10). p.9815-9829
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- A2
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Particle-mediated intravenous delivery of antigen mRNA results in strong antigen-specific T-cell responses despite the induction of type I interferon

Katrijn Broos, Kevin Vanderjeught, Janik Puttemans, Cleo Goyvaerts, Carlo Heirman, Heleen Dewitte (UGent) , Rein Verbeke (UGent) , Ine Lentacker (UGent) , Kris Thielemans and Karine Breckpot

(2016) MOLECULAR THERAPY-NUCLEIC ACIDS. 5.
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The tumor-associated antigen RHAMM (HMMR/CD168) is expressed by monocyte-derived dendritic cells and presented to T cells

Yannick Willemen, Johan M. J. Van den Bergh, Sarah Bonte (UGent) , Sebastien Anguille, Carlo Heirman, Barbara MH Stein, Herman Goossens, Tessa Kerre (UGent) , Kris Thielemans, Marc Peeters, et al.

(2016) ONCOTARGET. 7(45). p.73960-73970
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- Journal Article
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Intratumoral delivery of TriMix mRNA results in T-cell activation by cross-presenting dendritic cells

Sandra Van Lint (UGent) , Dries Renmans, Katrijn Broos, Lode Goethals, Sarah Maenhout, Daphné Benteyn, Cleo Goyvaerts, Stephanie Dufour, Kevin Van Der Jeught, Lukasz Bialkowski, et al.

(2016) CANCER IMMUNOLOGY RESEARCH. 4(2). p.146-156
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The ReNAissanCe of mRNA-based cancer therapy

Sandra Van Lint (UGent) , Dries Renmans, Katrijn Broos, Heleen Dewitte (UGent) , Ine Lentacker (UGent) , Carlo Heirman, Karine Breckpot and Kris Thielemans

(2015) EXPERT REVIEW OF VACCINES. 14(2). p.235-251
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Targeting the tumor microenvironment to enhance antitumor immune responses

Kevin Van Der Jeught, Lukasz Bialkowski, Lidia Daszkiewicz, Katrijn Broos, Cleo Goyvaerts, Dries Renmans, Sandra Van Lint (UGent) , Carlo Heirman, Kris Thielemans and Karine Breckpot

(2015) ONCOTARGET. 6(3). p.1359-1381
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The potential of antigen and TriMix sonoporation using mRNA-loaded microbubbles for ultrasound-triggered cancer immunotherapy

Heleen Dewitte (UGent) , Sandra Van Lint (UGent) , Carlo Heirman, Kris Thielemans, Stefaan De Smedt (UGent) , Karine Breckpot and Ine Lentacker (UGent)

(2014) JOURNAL OF CONTROLLED RELEASE. 194. p.28-36
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Optimized dendritic cell-based immunotherapy for melanoma: the TriMix-formula

Sandra Van Lint (UGent) , Sofie Wilgenhof, Carlo Heirman, Jurgen Corthals, Karine Breckpot, Aude Bonehill, Bart Neyns and Kris Thielemans

(2014) CANCER IMMUNOLOGY IMMUNOTHERAPY. 63(9). p.959-967
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Immunogenicity of targeted lentivectors

Cleo Goyvaerts, Kurt De Groeve, Sandra Van Lint (UGent) , Carlo Heirman, Jo A Vanginderachter, Patrick De Baetselier, Geert Raes, Kris Thielemans and Karine Breckpot

(2014) ONCOTARGET. 5(3). p.704-715
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In vitro generation of mature, naive antigen-specific CD8⁺ T cells with a single T-cell receptor by agonist selection

SYLVIA SNAUWAERT (UGent) , Greet Verstichel (UGent) , Sarah Bonte (UGent) , Glenn Goetgeluk (UGent) , Stijn Vanhee (UGent) , Yasmine Van Caeneghem (UGent) , Katrien De Mulder (UGent) , Carlo Heirman, Hans Stauss, Miriam HM Heemskerk, et al.

(2014) LEUKEMIA. 28(4). p.830-841
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- Miscellaneous
mRNA: from a chemical blueprint for protein production to an off-the-shelf therapeutic

Sandra Van Lint (UGent) , Carlo Heirman, Kris Thielemans and Karine Breckpot

(2013) HUMAN VACCINES & IMMUNOTHERAPEUTICS. 9(2). p.265-274
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Design of an optimized Wilms' tumor 1 (WT1) mRNA construct for enhanced WT1 expression and improved immunogenicity in vitro and in vivo

Daphné Benteyn, Sébastien Anguille, Sandra Van Lint (UGent) , Carlo Heirman, An MT Van Nuffel, Jurgen Corthals, Sebastian Ochsenreither, Wim Waelput, Katrien Van Beneden, Karine Breckpot, et al.

(2013) MOLECULAR THERAPY-NUCLEIC ACIDS. 2.
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Proinflammatory characteristics of SMAC/DIABLO-induced cell death in antitumor therapy

Perpetua U Emeagi, Sandra Van Lint (UGent) , Cleo Goyvaerts, Sarah Maenhout, Anje Cauwels (UGent) , Lain A McNeish, Tomas Bos, Carlo Heirman, Kris Thielennans, Joeri L Aerts, et al.

(2012) CANCER RESEARCH. 72(6). p.1342-1352
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Development of the nanobody display technology to target lentiviral vectors to antigen-presenting cells

Cleo Goyvaerts, Kurt De Groeve, Jozef Dingemans, Sandra Van Lint (UGent) , Lander Robays, Carlo Heirman, J Reiser, Kris Thielemans, Patrick De Baetselier, Geert Raes, et al.

(2012) GENE THERAPY. 19(12). p.1133-1140
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Preclinical evaluation of TriMix and antigen mRNA-based anti-tumor therapy

Sandra Van Lint (UGent) , Cleo Goyvaerts, Sarah Maenhout, Lode Goethals, Aurélie Disy, Daphné Benteyn, Joeri Pen, Aude Bonehill, Carlo Heirman, Karine Breckpot, et al.

(2012) CANCER RESEARCH. 72(7). p.1661-1671
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- Journal Article
- A1
Large double copy vectors are functional but show a size-dependent decline in transduction efficiency

Tomas J Bos, Sandra Van Lint (UGent) , Carlo Heirman and Karin Vanderkerken

(2010) JOURNAL OF BIOTECHNOLOGY. 150(1). p.37-40
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- Journal Article
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Attenuated Expression of A20 Markedly Increases the Efficacy of Double-Stranded RNA-Activated Dendritic Cells As an Anti-Cancer Vaccine

Karine Breckpot, Cindy Aerts-Toegaert, Carlo Heirman, Uschi Peeters, Rudi Beyaert (UGent) , Joeri L Aerts and Kris Thielemans

(2009) JOURNAL OF IMMUNOLOGY. 182(2). p.860-870
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- Journal Article
- A1
Activation of immature monocyte-derived dendritic cells after transduction with high doses of lentiviral vectors

Karine Breckpot, Perpetua Emeagi, Melissa Dullaers (UGent) , Annelies Michiels, Carlo Heirman and Kris Thielemans

(2007) HUMAN GENE THERAPY. 18(6). p.536-546
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- Journal Article
- A1
Induction of effective therapeutic antitumor immunity by direct in vivo administration of lentiviral vectors

Melissa Dullaers (UGent) , Sonja Van Meirvenne, Carlo Heirman, L Straetman, Aude Bonehill, JL Aerts, Kris Thielemans and Karine Breckpot

(2006) GENE THERAPY. 13(7). p.630-640
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- A1
In vivo depletion of CD4⁺CD25⁺ regulatory T cells enhances the antigen-specific primary and memory CTL response elicited by mature mRNA-electroporated dendritic cells

Sonja Van Meirvenne, Melissa Dullaers (UGent) , Carlo Heirman, Lieven Straetman, Annelies Michiels and Kris Thielemans

(2005) MOLECULAR THERAPY. 12(5). p.922-932
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- A1
Electroporation of immature and mature dendritic cells: implications for dendritic cell-based vaccines

A Michiels, S Tuyaerts, Aude Bonehill, J Corthals, Karine Breckpot, Carlo Heirman, Sonja Van Meirvenne, Melissa Dullaers (UGent) , S Allard, F Brasseur, et al.

(2005) GENE THERAPY. 12(9). p.772-782
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- Journal Article
- A1
Side-by-side comparison of lentivirally transduced and mRNA-electroporated dendritic cells: implications for cancer immunotherapy protocols

Melissa Dullaers (UGent) , Karine Breckpot, Sonja Van Meirvenne, Aude Bonehill, Sandra Tuyaerts, Annelies Michiels, Lieven Straetman, Carlo Heirman, Catherine De Greef, Pierre Van Der Bruggen, et al.

(2004) MOLECULAR THERAPY. 10(4). p.768-779
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- Journal Article
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Lentivirally transduced dendritic cells as a tool for cancer immunotherapy

Karine Breckpot, Melissa Dullaers (UGent) , Aude Bonehill, Sonja van Meirvenne, Carlo Heirman, Catherine de Greef, Pierre van der Bruggen and Kris Thielemans

(2003) JOURNAL OF GENE MEDICINE. 5(8). p.654-667
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Efficient genetic modification of murine dendritic cells by electroporation with mRNA

Sonja Van Meirvenne, Lieven Straetman, Carlo Heirman, Melissa Dullaers (UGent) , Catherine De Greef, Viggo Van Tendeloo and Kris Thielemans

(2002) CANCER GENE THERAPY. 9(9). p.787-797

Academic Bibliography

Intranodal administration of mRNA encoding nucleoprotein provides cross-strain immunity against influenza in mice

Vegf-A mRNA transfection as a novel approach to improve mouse and human islet graft revascularisation

Dendritic cell targeting mRNA lipopolyplexes combine strong antitumor T-cell immunity with improved inflammatory safety

Particle-mediated intravenous delivery of antigen mRNA results in strong antigen-specific T-cell responses despite the induction of type I interferon

The tumor-associated antigen RHAMM (HMMR/CD168) is expressed by monocyte-derived dendritic cells and presented to T cells

Intratumoral delivery of TriMix mRNA results in T-cell activation by cross-presenting dendritic cells

The ReNAissanCe of mRNA-based cancer therapy

Targeting the tumor microenvironment to enhance antitumor immune responses

The potential of antigen and TriMix sonoporation using mRNA-loaded microbubbles for ultrasound-triggered cancer immunotherapy

Optimized dendritic cell-based immunotherapy for melanoma: the TriMix-formula

Immunogenicity of targeted lentivectors

In vitro generation of mature, naive antigen-specific CD8⁺ T cells with a single T-cell receptor by agonist selection

mRNA: from a chemical blueprint for protein production to an off-the-shelf therapeutic

Design of an optimized Wilms' tumor 1 (WT1) mRNA construct for enhanced WT1 expression and improved immunogenicity in vitro and in vivo

Proinflammatory characteristics of SMAC/DIABLO-induced cell death in antitumor therapy

Development of the nanobody display technology to target lentiviral vectors to antigen-presenting cells

Preclinical evaluation of TriMix and antigen mRNA-based anti-tumor therapy

Large double copy vectors are functional but show a size-dependent decline in transduction efficiency

Attenuated Expression of A20 Markedly Increases the Efficacy of Double-Stranded RNA-Activated Dendritic Cells As an Anti-Cancer Vaccine

Activation of immature monocyte-derived dendritic cells after transduction with high doses of lentiviral vectors

Induction of effective therapeutic antitumor immunity by direct in vivo administration of lentiviral vectors

In vivo depletion of CD4⁺CD25⁺ regulatory T cells enhances the antigen-specific primary and memory CTL response elicited by mature mRNA-electroporated dendritic cells

Electroporation of immature and mature dendritic cells: implications for dendritic cell-based vaccines

Side-by-side comparison of lentivirally transduced and mRNA-electroporated dendritic cells: implications for cancer immunotherapy protocols

Lentivirally transduced dendritic cells as a tool for cancer immunotherapy

Efficient genetic modification of murine dendritic cells by electroporation with mRNA

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