Ghent University Academic Bibliography

GSDMD drives canonical inflammasome-induced neutrophil pyroptosis and is dispensable for NETosis

Dhruv Chauhan, Dieter Demon (UGent) , Lieselotte Vande Walle (UGent) , Oonagh Paerewijck (UGent) , Annalisa Zecchin, Leslie Bosseler, Karin Santoni, Remi Planes, Silvia Ribó Gené (UGent) , Amelie Fossoul (UGent) , et al.

(2022) EMBO REPORTS. 23(10).

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A1
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Bacillus anthracis induces NLRP3 inflammasome activation and caspase-8-mediated apoptosis of macrophages to promote lethal anthrax

Filip Van Hauwermeiren (UGent) , Nina Van Opdenbosch (UGent) , Hanne Van Gorp (UGent) , Nathalia de Vasconcelos, Geert van Loo (UGent) , Peter Vandenabeele (UGent) , Thirumala-Devi Kanneganti and Mohamed Lamkanfi (UGent)

(2022) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 119(2).

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Nanoparticle-sensitized photoporation enables inflammasome activation studies in targeted single cells dagger

Aranit Harizaj (UGent) , Filip Van Hauwermeiren (UGent) , Stephan Stremersch (UGent) , Riet De Rycke (UGent) , Herlinde De Keersmaecker (UGent) , Toon Brans (UGent) , Juan Fraire (UGent) , Karolien Grauwen, Stefaan De Smedt (UGent) , Ine Lentacker (UGent) , et al.

(2021) NANOSCALE. 13(13). p.6592-6604

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MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition

Lieselotte Vande Walle (UGent) , Irma B Stowe, Pavel Sacha, Bettina L Lee, Dieter Demon (UGent) , Amelie Fossoul (UGent) , Filip Van Hauwermeiren (UGent) , Pedro Henrique Viana Saavedra (UGent) , Petr Simon, Vladimir Subrt, et al.

(2019) PLOS BIOLOGY. 17(9).

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Structure of S-layer protein Sap reveals a mechanism for therapeutic intervention in anthrax

Antonella Fioravanti, Filip Van Hauwermeiren (UGent) , Sander E Van der Verren, Wim Jonckheere, Amanda Gonçalves (UGent) , Els Pardon, Jan Steyaert, Henri De Greve, Mohamed Lamkanfi (UGent) and Han Remaut

(2019) NATURE MICROBIOLOGY. 4(11). p.1805-1814

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Caspase-1 engagement and TLR-induced c-FLIP expression suppress ASC/caspase-8-dependent apoptosis by inflammasome sensors NLRP1b and NLRC4

Nina Van Opdenbosch (UGent) , Hanne Van Gorp (UGent) , Maarten Verdonckt (UGent) , Pedro Henrique Viana Saavedra (UGent) , Nathalia Moraes de Vasconcelos (UGent) , Amanda Gonçalves (UGent) , Lieselotte Vande Walle (UGent) , Dieter Demon (UGent) , Magdalena Matusiak (UGent) , Filip Van Hauwermeiren (UGent) , et al.

(2017) CELL REPORTS. 21(12). p.3427-3444

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Nlrp6-and ASC-dependent inflammasomes do not shape the commensal gut microbiota composition

Michail Mamantopoulos, Francesca Ronchi, Filip Van Hauwermeiren (UGent) , Sara Vieira-Silva, Bahtiyar Yilmaz, Liesbet Martens (UGent) , Yvan Saeys (UGent) , Stefan K Drexler, Amir S Yazdi, Jeroen Raes (UGent) , et al.

(2017) IMMUNITY. 47(2). p.339-348

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Inflammasomes in inflammatory disease

Hanne Van Gorp (UGent) , Pedro Henrique Viana Saavedra (UGent) , Nathalia Moraes de Vasconcelos (UGent) , Nina Van Opdenbosch (UGent) , Lieselotte Vande Walle (UGent) , Magdalena Matusiak (UGent) , Filip Van Hauwermeiren (UGent) , G. Prencipe, Delfien Bogaert (UGent) , Melissa Dullaers (UGent) , et al.

(2016) EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. In European Journal of Clinical Investigation 46(Supplement 1). p.99-99

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Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation

Hanne Van Gorp (UGent) , Pedro Henrique Viana Saavedra (UGent) , Nathalia Moraes de Vasconcelos (UGent) , Nina Van Opdenbosch (UGent) , Lieselotte Vande Walle (UGent) , Magdalena Matusiak (UGent) , Giusi Prencipe, Antonella Insalaco, Filip Van Hauwermeiren (UGent) , Dieter Demon (UGent) , et al.

(2016) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 113(50). p.14384-14389

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Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation

Lien Dejager (UGent) , Karen Dendoncker (UGent) , Melanie Eggermont (UGent) , Jolien Souffriau, Filip Van Hauwermeiren (UGent) , Monique Willart (UGent) , Elien Van Wonterghem (UGent) , Thomas Naessens (UGent) , Marlies Ballegeer (UGent) , Sofie Vandevyver (UGent) , et al.

(2015) MUCOSAL IMMUNOLOGY. 8(6). p.1212-1225

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Glucocorticoid-induced microRNA-511 protects against TNF by down-regulating TNFR1

Leen Puimège (UGent) , Filip Van Hauwermeiren (UGent) , Sophie Steeland (UGent) , Sara Van Ryckeghem (UGent) , Jolien Vandewalle (UGent) , Sofie Lodens, Lien Dejager (UGent) , Sofie Vandevyver (UGent) , Jan Staelens, Steven Timmermans (UGent) , et al.

(2015) EMBO MOLECULAR MEDICINE. 7(8). p.1004-1017

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Regulation and dysregulation of tumor necrosis factor receptor-1

Leen Puimège (UGent) , Claude Libert (UGent) and Filip Van Hauwermeiren (UGent)

(2014) CYTOKINE & GROWTH FACTOR REVIEWS. 25(3). p.285-300

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Pro-inflammatory effects of matrix metalloproteinase 7 in acute inflammation

Roosmarijn Vandenbroucke (UGent) , Ineke Vanlaere (UGent) , Filip Van Hauwermeiren (UGent) , Elien Van Wonterghem (UGent) , C Wilson and Claude Libert (UGent)

(2014) MUCOSAL IMMUNOLOGY. 7(3). p.579-588

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LPS resistance of SPRET/Ei mice is mediated by Gilz, encoded by the Tsc22d3 gene on the X chromosome

Iris Pinheiro, Lien Dejager (UGent) , Ioanna Petta (UGent) , Sofie Vandevyver (UGent) , Leen Puimège (UGent) , Tina Mahieu, Marlies Ballegeer (UGent) , Filip Van Hauwermeiren (UGent) , Carlo Riccardi, Marnik Vuylsteke (UGent) , et al.

(2013) EMBO MOLECULAR MEDICINE. 5(3). p.456-470

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Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF

Roosmarijn Vandenbroucke (UGent) , Eline Dejonckheere (UGent) , Filip Van Hauwermeiren (UGent) , Sofie Lodens, Riet De Rycke (UGent) , Elien Van Wonterghem (UGent) , An Staes (UGent) , Kris Gevaert (UGent) , Carlos López-Otin and Claude Libert (UGent)

(2013) EMBO MOLECULAR MEDICINE. 5(7). p.1000-1016

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Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium

Filip Van Hauwermeiren (UGent) , Marietta Armaka, Niki Karagianni, Ksanthi Kranidioti, Roosmarijn Vandenbroucke (UGent) , Sonja Loges, Maarten Van Royen (UGent) , Jan Staelens, Leen Puimège (UGent) , Ajay Palagani, et al.

(2013) JOURNAL OF CLINICAL INVESTIGATION. 123(6). p.2590-2603

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Treatment of TNF mediated diseases by selective inhibition of soluble TNF or TNFR1

Filip Van Hauwermeiren (UGent) , Roosmarijn Vandenbroucke (UGent) and Claude Libert (UGent)

(2011) CYTOKINE & GROWTH FACTOR REVIEWS. 22(5-6). p.311-319

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PhD Thesis

New strategies to prevent TNF-induced toxicity in TNF/IFNγ-based anti-tumor models

Filip Van Hauwermeiren (UGent)

(2011)

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Endothelial outgrowth cells are not derived from CD133(+) cells or CD45(+) hematopoietic precursors

Frank Timmermans (UGent) , Filip Van Hauwermeiren (UGent) , Magda De Smedt (UGent) , Robrecht Raedt (UGent) , Frank Plasschaert, Marc De Buyzere (UGent) , Thierry Gillebert (UGent) , Jean Plum (UGent) and Bart Vandekerckhove (UGent)

(2007) ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 27(7). p.1572-1579

Academic Bibliography

GSDMD drives canonical inflammasome-induced neutrophil pyroptosis and is dispensable for NETosis

Bacillus anthracis induces NLRP3 inflammasome activation and caspase-8-mediated apoptosis of macrophages to promote lethal anthrax

Nanoparticle-sensitized photoporation enables inflammasome activation studies in targeted single cells dagger

MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition

Structure of S-layer protein Sap reveals a mechanism for therapeutic intervention in anthrax

Caspase-1 engagement and TLR-induced c-FLIP expression suppress ASC/caspase-8-dependent apoptosis by inflammasome sensors NLRP1b and NLRC4

Nlrp6-and ASC-dependent inflammasomes do not shape the commensal gut microbiota composition

Inflammasomes in inflammatory disease

Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation

Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation

Glucocorticoid-induced microRNA-511 protects against TNF by down-regulating TNFR1

Regulation and dysregulation of tumor necrosis factor receptor-1

Pro-inflammatory effects of matrix metalloproteinase 7 in acute inflammation

LPS resistance of SPRET/Ei mice is mediated by Gilz, encoded by the Tsc22d3 gene on the X chromosome

Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF

Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium

Treatment of TNF mediated diseases by selective inhibition of soluble TNF or TNFR1

New strategies to prevent TNF-induced toxicity in TNF/IFNγ-based anti-tumor models

Endothelial outgrowth cells are not derived from CD133(+) cells or CD45(+) hematopoietic precursors

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