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Dual-acting small molecules : subtype-selective cannabinoid receptor 2 agonist/butyrylcholinesterase inhibitor hybrids show neuroprotection in an Alzheimer's disease mouse model
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Application of a fully automated dried blood spot method for therapeutic drug monitoring of immunosuppressants
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Off-target activity of NBOMes and NBOMe analogs at the mu opioid receptor
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A protocol for a turbidimetric assay using a Saccharomyces cerevisiae thiamin biosynthesis mutant to estimate total vitamin B1 content in plant tissue samples
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Are the N-demethylated metabolites of U-47700 more active than their parent compound? In vitro mu-opioid receptor activation of N-desmethyl-U-47700 and N,N-bisdesmethyl-U-47700
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A novel panel of yeast assays for the assessment of thiamin and its biosynthetic intermediates in plant tissues
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Cov²MS : an automated and quantitative matrix-independent assay for mass spectrometric measurement of SARS-CoV-2 nucleocapsid protein
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The P2Y(2) receptor C-terminal tail modulates but is dispensable for beta-arrestin recruitment
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A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs
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First identification, chemical analysis and pharmacological characterization of N-piperidinyl etonitazene (etonitazepipne), a recent addition to the 2-benzylbenzimidazole opioid subclass
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In vitro assays for the functional characterization of (psychedelic) substances at the serotonin receptor 5-HT2AR
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Toxicological and pharmacological characterization of novel cinnamylpiperazine synthetic opioids in humans and in vitro including 2-methyl AP-237 and AP-238
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Metabolic engineering of rice endosperm towards higher vitamin B1 accumulation
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Metabolic engineering provides insight into the regulation of thiamin biosynthesis in plants
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An optimized LC-MS/MS method as a pivotal tool to steer thiamine biofortification strategies in rice
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Shape matters : the application of activity-based in vitro bioassays and chiral profiling to the pharmacological evaluation of synthetic cannabinoid receptor agonists in drug-infused papers seized in prisons
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Diagnosing intake and rationalizing toxicities associated with 5F-MDMB-PINACA and 4F-MDMB-BINACA abuse
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The next generation of synthetic cannabinoids : detection, activity, and potential toxicity of pent-4en and but-3en analogues including MDMB-4en-PINACA
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A novel nanobody-based bio-assay using functional complementation of a split nanoluciferase to monitor Mu- opioid receptor activation
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In vitro functional characterization of a panel of non-fentanyl opioid new psychoactive substances