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Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children
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The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies
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- Journal Article
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Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia
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- Journal Article
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Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths
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Expansion, in vivo-ex vivo cycling, and genetic manipulation of primary human hepatocytes
(2020) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 117(3). p.1678-1688 -
- Journal Article
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Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice
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Autoantibodies against type I IFNs in patients with life-threatening COVID-19
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Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
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- Journal Article
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Expanding the host range of hepatitis C virus through viral adaptation
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Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture
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Successful anti-scavenger receptor class B type I (SR-BI) monoclonal antibody therapy in humanized mice after challenge with HCV variants with in vitro resistance to SR-BI-targeting agents
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Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells
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A human monoclonal antibody targeting scavenger receptor class B type I precludes hepatitis C virus infection and viral spread in vitro and in vivo