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Mitotic dysregulation at tumor initiation creates a therapeutic vulnerability to combination anti-mitotic and pro-apoptotic agents for MYCN-driven neuroblastoma
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High-fat diet and estrogen modulate the gut microbiota in a sex-dependent manner in mice
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Hsa-miR-665 is a promising biomarker in cancer prognosis
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The activation of JAK/STAT3 signaling and the complement system modulate inflammation in the primary human dermal fibroblasts of PXE patients
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Candidate RNA biomarkers in biofluids for early diagnosis of ovarian cancer : a systematic review
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International Cancer Microbiome Consortium consensus statement on the role of the human microbiome in carcinogenesis
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Accurate detection and quantification of epigenetic and genetic second hits in BRCA1 and BRCA2-associated hereditary breast and ovarian cancer reveals multiple co-acting second hits
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The transcriptome of lung tumor-infiltrating dendritic cells reveals a tumor-supporting phenotype and a microRNA signature with negative impact on clinical outcome
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Accurate quantification of homologous recombination in zebrafish : brca2 deficiency as a paradigm
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The REG gamma-proteasome forms a regulatory circuit with I kappa B epsilon and NF kappa B in experimental colitis
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Glutathione biosynthesis is upregulated at the initiation of MYCN-driven neuroblastoma tumorigenesis
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OTUB1 triggers lung cancer development by inhibiting RAS monoubiquitination
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The prosurvival IKK-related kinase IKKε integrates LPS and IL17A signaling cascades to promote Wnt-dependent tumor development in the intestine
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Loss of autocrine endothelial-derived VEGF significantly reduces hemangiosarcoma development in conditional p53-deficient mice
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Salmonella exploits NLRP12-dependent innate immune signaling to suppress host defenses during infection
(2014) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 111(1). p.385-390 -
Lung tumours reprogram pulmonary dendritic cell immunogenicity at the microRNA level
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Cancer-associated adipose tissue promotes breast cancer progression by paracrine Oncostatin M and Jak/STAT3 signaling
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EMT as the ultimate survival mechanism of cancer cells
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Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation
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Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria
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Expression of the ACTH receptor, steroidogenic acute regulatory protein, and steroidogenic enzymes in canine cortisol-secreting adrenocortical tumors
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Central role of c-Myc during malignant conversion in human hepatocarcinogenesis
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Molecular and functional consequences of Smad4 C-terminal missense mutations in colorectal tumour cells
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Loss of membranous expression of β-catenin is associated with tumor progression in cutaneous melanoma and rarely caused by Exon 3 mutations