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Optimizing the use of antibiotic agents in the pediatric intensive care unit : a narrative review
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Antimicrobial de-escalation as part of antimicrobial stewardship in intensive care : no simple answers to simple questions - a viewpoint of experts
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- Journal Article
- A1
- open access
Antimicrobial de-escalation in the ICU : from recommendations to level of evidence
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Population pharmacokinetics and evaluation of the predictive performance of pharmacokinetic models in critically ill patients receiving continuous infusion meropenem : a comparison of eight pharmacokinetic models
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Subtherapeutic piperacillin concentrations in neurocritical patients
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Early target attainment of continuous infusion piperacillin/tazobactam and meropenem in critically ill patients : a prospective observational study
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Saturable elimination of piperacillin in critically ill patients : implications for continuous infusion
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Measuring antibiotics in exhaled air in critically ill, non-ventilated patients : a feasibility and proof of concept study
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Measuring unbound versus total piperacillin concentrations in plasma of critically ill patients : methodological issues and relevance
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- Journal Article
- A1
- open access
The effects of major burn related pathophysiological changes on the pharmacokinetics and pharmacodynamics of drug use : an appraisal utilizing antibiotics
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Targeting the nonmevalonate pathway in Burkholderia cenocepacia increases susceptibility to certain β-lactam antibiotics
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Stability of amoxicillin and amoxicillin/clavulanic acid reconstituted in isotonic saline
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Small-molecule potentiators for conventional antibiotics against Staphylococcus aureus
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Dose optimization of piperacillin/tazobactam in critically ill children
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Impact of de-escalation of beta-lactam antibiotics on the emergence of antibiotic resistance in ICU patients : a retrospective observational study
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Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? : an observation from the Defining Antibiotic Levels in Intensive care unit patients (DALI) cohort
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Evaluation and validation of the use of a molecularly imprinted polymer coupled to LC-MS for benzylpenicillin determination in meat samples
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In vivo diagnosis of allergic diseases-allergen provocation tests
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Population pharmacokinetics and dosing simulations of cefepime in septic shock patients receiving continuous renal replacement therapy
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A simulation study reveals lack of pharmacokinetic/pharmacodynamic target attainment in de-escalated antibiotic therapy in critically ill patients
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Augmented renal clearance implies a need for increased amoxicillin-clavulanic acid dosing in critically ill children
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- Journal Article
- A1
- open access
Role of therapeutic drug monitoring in pulmonary infections : use and potential for expanded use of dried blood spot samples
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Stability of generic brands of meropenem reconstituted in isotonic saline
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Ultrafast quantification of β-lactam antibiotics in human plasma using UPLC-MS/MS
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- PhD Thesis
- open access
Patient tailored antibiotic therapy in critically ill patients
(2015) -
Basophil activation tests: time for a reconsideration
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Antimicrobial stewardship of β-lactams in intensive care units
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Therapeutic drug monitoring-based dose optimisation of piperacillin and meropenem: a randomised controlled trial
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Extended versus bolus infusion of meropenem and piperacillin: a pharmacokinetic analysis
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Population pharmacokinetics and dosing simulations of cefuroxime in critically ill patients: non-standard dosing approaches are required to achieve therapeutic exposures
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Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients
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Development and validation of a fast and uniform approach to quantify β-lactam antibiotics in human plasma by solid phase extraction-liquid chromatography-electrospray-tandem mass spectrometry
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- Journal Article
- A1
- open access
Meropenem and piperacillin/tazobactam prescribing in critically ill patients : does augmented renal clearance affect pharmacokinetic/pharmacodynamic target attainment when extended infusions are used?
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Is repositioning of drugs a viable alternative in the treatment of tuberculosis?
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Essentials for selecting antimicrobial therapy for intra-abdominal infections
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Quantification of seven β-lactam antibiotics and two β-lactamase inhibitors in human plasma using a validated UPLC-MS/MS method
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- Journal Article
- A1
- open access
Synthesis of 2-amino-3-arylpropan-1-ols and 1-(2,3-diaminopropyl)-1,2,3-triazoles and evaluation of their antimalarial activity
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- Journal Article
- A1
- open access
Methicillin-resistant Staphylococcus aureus (MRSA) in food production animals
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Influence of administration route on the biotransformation of amoxicillin in the pig
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Residue analysis: future trends from a historical perspective