Ghent University Academic Bibliography

Your filters: cql: author exact F4388FA4-F0ED-11E1-A9DE-61C894A0A6B4

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HTSplotter : an end-to-end data processing, analysis and visualisation tool for chemical and genetic in vitro perturbation screening

Carolina de Carvalho Nunes (UGent) , Jasper Anckaert (UGent) , Fanny De Vloed (UGent) , Jolien De Wyn, Kaat Durinck (UGent) , Jo Vandesompele (UGent) , Franki Speleman (UGent) and Vanessa Vermeirssen (UGent)

(2024) PLOS ONE. 19(1).
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MYCN and SNRPD3 cooperate to maintain a balance of alternative splicing events that drives neuroblastoma progression

Alice Salib, Nisitha Jayatilleke, Janith A. Seneviratne, Chelsea Mayoh, Katleen De Preter (UGent) , Franki Speleman (UGent) , Belamy B. Cheung, Daniel R. Carter and Glenn M. Marshall

(2024) ONCOGENE. 43(5). p.363-377
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Preclinical exploration of the DNA damage response pathway using the interactive neuroblastoma cell line explorer CLEAN

Jonatan Linus Gabre (UGent) , Peter Merseburger (UGent) , Arne Claeys (UGent) , Joachim Siaw (UGent) , Sarah-Lee Bekaert (UGent) , Franki Speleman (UGent) , Bengt Hallberg, Ruth H Palmer and Jimmy Van den Eynden (UGent)

(2024) NAR CANCER. 6(1).
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Human iPSC modeling recapitulates in vivo sympathoadrenal development and reveals an aberrant developmental subpopulation in familial neuroblastoma

Stéphane Van Haver (UGent) , Yujie Fan, Sarah-Lee Bekaert (UGent) , Celine Everaert (UGent) , Wouter Van Loocke (UGent) , Vittorio Zanzani (UGent) , Joke Deschildre (UGent) , Ines Fernandez Maestre, Adrianna Amaro, Vanessa Vermeirssen (UGent) , et al.

(2024) ISCIENCE. 27(1).
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Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma

Jordan F. Hastings, Sharissa L. Latham, Alvin Kamili, Madeleine S. Wheatley, Jeremy Z. R. Han, Marie Wong-Erasmus, Monica Phimmachanh, Max Nobis, Chiara Pantarelli, Antonia L. Cadell, et al.

(2023) SCIENCE ADVANCES. 9(9).
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Mitotic dysregulation at tumor initiation creates a therapeutic vulnerability to combination anti-mitotic and pro-apoptotic agents for MYCN-driven neuroblastoma

Lei Zhai, Anushree Balachandran, Rebecca Larkin, Janith A. Seneviratne, Sylvia A. Chung, Amit Lalwani, Shoma Tsubota, Dominik Beck, Kenji Kadomatsu, Anneleen Beckers (UGent) , et al.

(2023) INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 24(21).
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Exploration of neuroblastoma xenograft models for tumor extracellular RNA profiling in murine blood plasma

Jill Deleu (UGent) , Hanne Van Droogenbroeck (UGent) , Jasper Anckaert (UGent) , Anneleen Decock (UGent) , Jilke De Wilde (UGent) , Kaat Durinck (UGent) , Liselot Mus (UGent) , Justine Nuytens (UGent) , Muhammad Rishfi (UGent) , Kathleen Schoofs (UGent) , et al.

(2023) EXRNA. 5(2).
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Exploration of neuroblastoma xenograft models for the analysis of tumoral cell-free RNA in murine blood plasma

Jill Deleu (UGent) , Hanne Van Droogenbroeck (UGent) , Jasper Anckaert (UGent) , Jilke De Wilde (UGent) , Kaat Durinck (UGent) , Liselot Mus (UGent) , Justine Nuytens (UGent) , Muhammad Rishfi (UGent) , Kathleen Schoofs (UGent) , Franki Speleman (UGent) , et al.

(2023) Advances in Neuroblastoma Research (ANR) Meeting 2023, Abstracts.
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Longitudinal evaluation of serum microRNAs as biomarkers for neuroblastoma burden and therapeutic p53 reactivation

Alan Van Goethem (UGent) , Jill Deleu (UGent) , Nurten Yigit (UGent) , Celine Everaert (UGent) , Myrthala Moreno-Smith, Sanjeev A Vasudevan, Fjoralba Zeka (UGent) , Fleur Demuynck (UGent) , Eveline Barbieri, Franki Speleman (UGent) , et al.

(2023) NAR CANCER. 5(1).
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A harmonized single-cell transcriptomic atlas of human neuroblastoma

Noah Bonine (UGent) , Vittorio Zanzani (UGent) , Liselot Mus (UGent) , Bavo Vanneste (UGent) , Christian Zwicker (UGent) , Tinne Thoné (UGent) , Sofie Roelandt (UGent) , Cécile Thirant, Amira Kramdi, Isabelle Janoueix-Lerosey, et al.

(2023) Advances in Neuroblastoma Research (ANR) Meeting 2023, Abstracts.
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Whole transcriptome profiling of liquid biopsies from tumour xenografted mouse models enables specific monitoring of tumour-derived extracellular RNA

Vanessa Vermeirssen (UGent) , Jill Deleu (UGent) , Annelien Morlion (UGent) , Celine Everaert (UGent) , Jilke De Wilde (UGent) , Jasper Anckaert (UGent) , Kaat Durinck (UGent) , Justine Nuytens (UGent) , Muhammad Rishfi (UGent) , Franki Speleman (UGent) , et al.

(2023)
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SOX11 regulates SWI/SNF complex components as member of the adrenergic neuroblastoma core regulatory circuitry

Bieke Decaesteker (UGent) , Amber Louwagie (UGent) , Siebe Loontiens (UGent) , Fanny De Vloed (UGent) , Sarah-Lee Bekaert (UGent) , Juliette Roels (UGent) , Suzanne Vanhauwaert (UGent) , Sara De Brouwer (UGent) , Ellen Sanders, A Berezovskaya, et al.

(2023) NATURE COMMUNICATIONS. 14(1).
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Exploration of neuroblastoma xenograft models for tumor extracellular RNA profiling in murine blood plasma

Jill Deleu (UGent) , Vanessa Vermeirssen (UGent) , Annelien Morlion (UGent) , Celine Everaert (UGent) , Jilke De Wilde (UGent) , Jasper Anckaert (UGent) , Kaat Durinck (UGent) , Justine Nuytens (UGent) , Muhammad Rishfi (UGent) , Franki Speleman (UGent) , et al.

(2022)
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Complementarity of single-nucleus and single-cell RNA sequencing to study the transcriptional heterogeneity of neuroblastoma tumors

Noah Bonine (UGent) , Tinne Thoné (UGent) , Bavo Vanneste (UGent) , Liselot Mus (UGent) , Celine Everaert (UGent) , Bram De Wilde (UGent) , Franki Speleman (UGent) , Charlotte Scott (UGent) and Katleen De Preter (UGent)

(2022) EMBO Workshop 'Cancer cell signaling : Linking molecular knowledge to cancer therapy', Abstracts.
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Complementarity of single-nucleus and single-cell RNA sequencing to study the transcriptional heterogeneity of neuroblastoma tumors

Noah Bonine (UGent) , Tinne Thoné (UGent) , Bavo Vanneste (UGent) , Liselot Mus (UGent) , Celine Everaert (UGent) , Bram De Wilde (UGent) , Franki Speleman (UGent) , Charlotte Scott (UGent) and Katleen De Preter (UGent)

(2022) Single Cell Network Ghent (SING) kick-off event, Abstracts.
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Cellular senescence in neuroblastoma

Sofia Zanotti, Bieke Decaesteker (UGent) , Suzanne Vanhauwaert (UGent) , Bram De Wilde (UGent) , Winnok De Vos and Franki Speleman (UGent)

(2022) BRITISH JOURNAL OF CANCER. 126(11). p.1529-1538
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HTSplotter : an end-to-end data processing, analysis and visualisation tool for chemical and genetic in vitro perturbation screening

Carolina de Carvalho Nunes (UGent) , Jasper Anckaert (UGent) , Fanny De Vloed (UGent) , Jolien De Wyn, Kaat Durinck (UGent) , Jo Vandesompele (UGent) , Franki Speleman (UGent) and Vanessa Vermeirssen (UGent)

(2022) BIORXIV.
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RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition

Carolina de Carvalho Nunes (UGent) , Lisa Depestel (UGent) , Liselot Mus (UGent) , Kaylee M. Keller, Louis Delhaye (UGent) , Amber Louwagie (UGent) , Muhammad Rishfi (UGent) , Alex Whale, Neesha Kara, Simon R. Andrews, et al.

(2022) SCIENCE ADVANCES. 8(28).
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The adrenergic-specific long non-coding RNA NESPR controls survival of neuroblastoma cells

Louis Delhaye (UGent) , Eric de Bony de Lavergne (UGent) , Dries Rombaut, Lim Fang Qi, Bieke Decaesteker (UGent) , Lisa Depestel (UGent) , Amber Louwagie (UGent) , Eva D'haene (UGent) , Pieter-Jan Volders (UGent) , Nurten Yigit (UGent) , et al.

(2022) OncoPoint Symposium, 8th, Abstracts.
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RRM2 enhances MYCN driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition

Lisa Depestel (UGent) , Carolina de Carvalho Nunes (UGent) , Liselot Mus (UGent) , Iris Nelen (UGent) , Louis Delhaye (UGent) , Kaylee Keller, Volodimir Olexiouk, Fanny De Vloed (UGent) , Ellen Sanders (UGent) , Aline Eggermont (UGent) , et al.

(2022) OncoPoint Symposium, 8th, Abstracts.
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The feasibility of using liquid biopsies as a complementary assay for copy number aberration profiling in routinely collected paediatric cancer patient samples

Ruben Van Paemel (UGent) , Charlotte Vandeputte, Lennart Raman, Jolien Van Thorre, Leen Willems (UGent) , Jo Van Dorpe (UGent) , Malaïka Van der Linden (UGent) , Jilke De Wilde (UGent) , Andries De Koker (UGent) , Björn Menten (UGent) , et al.

(2022) EUROPEAN JOURNAL OF CANCER. 160. p.12-23
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Whole transcriptome profiling of liquid biopsies from tumour xenografted mouse models enables specific monitoring of tumour-derived extracellular RNA

Vanessa Vermeirssen (UGent) , Jill Deleu (UGent) , Annelien Morlion (UGent) , Celine Everaert (UGent) , Jilke De Wilde (UGent) , Jasper Anckaert (UGent) , Kaat Durinck (UGent) , Justine Nuytens (UGent) , Muhammad Rishfi (UGent) , Franki Speleman (UGent) , et al.

(2022) NAR CANCER. 4(4).
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Exploration of neuroblastoma xenograft models for tumor extracellular RNA profiling in murine blood plasma

Vanessa Vermeirssen (UGent) , Jill Deleu (UGent) , Annelien Morlion (UGent) , Celine Everaert (UGent) , Jilke De Wilde (UGent) , Jasper Anckaert (UGent) , Kaat Durinck (UGent) , Justine Nuytens (UGent) , Muhammad Rishfi (UGent) , Franki Speleman (UGent) , et al.

(2022)
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Whole transcriptome profiling of liquid biopsies from tumour xenografted mouse models enables specific monitoring of tumour-derived extracellular RNA

Vanessa Vermeirssen (UGent) , Jill Deleu (UGent) , Annelien Morlion (UGent) , Celine Everaert (UGent) , Jilke De Wilde (UGent) , Jasper Anckaert (UGent) , Kaat Durinck (UGent) , Justine Nuytens (UGent) , Muhammad Rishfi (UGent) , Franki Speleman (UGent) , et al.

(2022)
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From DNA copy number gains and tumor dependencies to novel therapeutic targets for high-risk neuroblastoma

Bieke Decaesteker (UGent) , Kaat Durinck (UGent) , Nadine Van Roy (UGent) , Bram De Wilde (UGent) , Christophe Van Neste (UGent) , Stéphane Van Haver (UGent) , Stephen Roberts, Katleen De Preter (UGent) , Vanessa Vermeirssen (UGent) and Franki Speleman (UGent)

(2021) JOURNAL OF PERSONALIZED MEDICINE. 11(12).
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A G316A polymorphism in the ornithine decarboxylase gene promoter modulates MYCN-driven childhood neuroblastoma

Laura D. Gamble, Stefania Purgato, Michelle J. Henderson, Simone Di Giacomo, Amanda J. Russell, Paolo Pigini, Jayne Murray, Emanuele Valli, Giorgio Milazzo, Federico M. Giorgi, et al.

(2021) CANCERS. 13(8).
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Kalirin-RAC controls nucleokinetic migration in ADRN-type neuroblastoma

Elena A Afanasyeva, Moritz Gartlgruber, Tatsiana Ryl, Bieke Decaesteker (UGent) , Geertrui Denecker (UGent) , Gregor Mönke, Umut H Toprak, Andres Florez, Alica Torkov, Daniel Dreidax, et al.

(2021) LIFE SCIENCE ALLIANCE. 4(5).
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SOX11 as guardian of epigenetic plasticity in neuroblastoma

Bieke Decaesteker (UGent) , Amber Louwagie (UGent) , Siebe Loontiens (UGent) , Sara De Brouwer, Carolina de Carvalho Nunes (UGent) , Geertrui Denecker (UGent) , Fanny De Vloed (UGent) , Lisa Depestel (UGent) , Juliette Roels (UGent) , Karen Verboom, et al.

(2021) Advances in Neuroblastoma Research (ANR 2021), Abstracts.
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MYCN-induced nucleolar stress drives an early senescence-like transcriptional program in hTERT-immortalized RPE cells

Sofia Zanotti, Suzanne Vanhauwaert (UGent) , Christophe Van Neste (UGent) , Volodimir Olexiouk (UGent) , Jolien Van Laere (UGent) , Marlies Verschuuren, Joni Van der Meulen (UGent) , Liselot Mus (UGent) , Kaat Durinck (UGent) , Laurentijn Tilleman (UGent) , et al.

(2021) SCIENTIFIC REPORTS. 11(1).
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PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis

E. G. Garcia, A. Veloso, M. L. Oliveira, J. R. Allen, S. Loontiens, D. Brunson, D. Do, C. Yan, R. Morris, S. Iyer, et al.

(2021) LEUKEMIA. 35. p.679-690
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Recurrent chromosomal imbalances provide selective advantage to human embryonic stem cells under enhanced replicative stress conditions

Liselot Mus (UGent) , Stéphane Van Haver (UGent) , Mina Popovic, Wim Trypsteen (UGent) , Steve Lefever (UGent) , Nadja Zeltner, Yudelca Ogando, Eva Jacobs, Geertrui Denecker (UGent) , Ellen Sanders (UGent) , et al.

(2021) GENES CHROMOSOMES & CANCER. 60(4). p.272-281
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The functional annotation and exploration the SOX11 enhanceosome

Amber Louwagie (UGent) , Bieke Decaesteker (UGent) , Louis Delhaye (UGent) , Eva D'haene (UGent) , Eric de Bony de Lavergne (UGent) , Volodimir Olexiouk (UGent) , Sarah Vergult (UGent) , Rogier Versteeg, Jan Koster, Johan van Nes, et al.

(2021) Advances in Neuroblastoma Research (ANR 2021), Abstracts.
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MEIS2 is an adrenergic core regulatory transcription factor involved in early initiation of TH-MYCN-driven neuroblastoma formation

Jolien De Wyn, Mark W. Zimmerman, Nina Weichert-Leahey, Carolina de Carvalho Nunes (UGent) , Belamy B. Cheung, Brian J. Abraham, Anneleen Beckers (UGent) , Pieter-Jan Volders (UGent) , Bieke Decaesteker (UGent) , Daniel R. Carter, et al.

(2021) CANCERS. 13(19).
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Accelerating drug development for neuroblastoma : summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma

Lucas Moreno, Giuseppe Barone, Steven G. DuBois, Jan Molenaar, Matthias Fischer, Johannes Schulte, Angelika Eggert, Gudrun Schleiermacher, Franki Speleman (UGent) , Louis Chesler, et al.

(2020) EUROPEAN JOURNAL OF CANCER. 136. p.52-68
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SOX11 as guardian of epigenetic plasticity in neuroblastoma

Bieke Decaesteker (UGent) , Amber Louwagie (UGent) , Siebe Loontiens (UGent) , Carolina de Carvalho Nunes (UGent) , Karen Verboom, Juliette Roels (UGent) , Eva D'haene (UGent) , Rogier Versteeg, Kaat Durinck (UGent) , Anton Henssen, et al.

(2020) Keystone Symposia Cancer Epigenetics : New Mechanisms and Therapeutic Opportunities, Abstracts.
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A novel TLX1-driven T-ALL zebrafish model : comparative genomic analysis with other leukemia models

Siebe Loontiens (UGent) , Suzanne Vanhauwaert (UGent) , Lisa Depestel (UGent) , Givani Dewyn (UGent) , Wouter Van Loocke (UGent) , Finola E. Moore, Elaine G. Garcia, Lance Batchelor, Chiara Borga, Barbara Squiban, et al.

(2020) LEUKEMIA. 34(12). p.3398-3403
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Large-scale circular RNA deregulation in T-ALL : unlocking unique ectopic expression of molecular subtypes

Alessia Buratin, Maddalena Paganin, Enrico Gaffo, Anna Dal Molin, Juliette Roels (UGent) , Giuseppe Germano, Maria Teresa Siddi, Valentina Serafin, Matthias De Decker, Stéphanie Gachet, et al.

(2020) BLOOD ADVANCES. 4(23). p.5902-5914
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Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development

Anne-Catherine Dolens, Kaat Durinck (UGent) , Marieke Lavaert, Joni Van der Meulen (UGent) , Imke Velghe (UGent) , Jelle De Medts (UGent) , Karin Weening (UGent) , Juliette Roels (UGent) , Katrien De Mulder (UGent) , Pieter-Jan Volders (UGent) , et al.

(2020) EMBO REPORTS. 21(5).
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PHF6 expression levels impact human hematopoietic stem cell differentiation

Siebe Loontiens (UGent) , Anne-Catherine Dolens, Steven Strubbe, Inge Van de Walle (UGent) , Finola E. Moore, Lisa Depestel (UGent) , Suzanne Vanhauwaert (UGent) , Filip Matthijssens (UGent) , David M. Langenau, Franki Speleman (UGent) , et al.

(2020) FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 8.
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The ETS transcription factor ETV5 is a target of activated ALK in neuroblastoma contributing to increased tumour aggressiveness

Liselot Mus (UGent) , Irina Lambertz (UGent) , Shana Claeys (UGent) , Candy Kumps (UGent) , Wouter Van Loocke (UGent) , Christophe Van Neste (UGent) , Ganesh Umapathy, Marica Vaapil, Christoph Bartenhagen, Genevieve Laureys (UGent) , et al.

(2020) SCIENTIFIC REPORTS. 10.
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The pitfalls and promise of liquid biopsies for diagnosing and treating solid tumors in children : a review

Ruben Van Paemel (UGent) , ROSALIE VLUG, Katleen De Preter (UGent) , Nadine Van Roy (UGent) , Franki Speleman (UGent) , Leen Willems (UGent) , Tim Lammens (UGent) , Genevieve Laureys (UGent) , Gudrun Schleiermacher, Godelieve AM Tytgat, et al.

(2020) EUROPEAN JOURNAL OF PEDIATRICS. 179(2). p.191-202
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Long noncoding RNA SILC1 is an upstream regulator of SOX11 in neuroblastoma

Amber Louwagie (UGent) , Bieke Decaesteker (UGent) , Eva D'haene (UGent) , Louis Delhaye (UGent) , Eric de Bony de Lavergne (UGent) , Christophe Van Neste (UGent) , Rogier Versteeg, Sara Ek, Björn Menten (UGent) , Jan Koster, et al.

(2020) 2020 Keystone Symposia Cancer Epigenetics : New Mechanisms and Therapeutic Opportunities, Abstracts.
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MYCN activation in hTERT immortalized RPE cells as model for oncogene induced senescence

Sofia Zanotti, Bieke Decaesteker (UGent) , Suzanne Vanhauwaert (UGent) , Michael D Hogarty, Volodimir Olexiouk (UGent) , Kaat Durinck (UGent) , Winnok De Vos and Franki Speleman (UGent)

(2019) Belgian Society for Human Genetics, 19th Annual meeting, Abstracts.
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Comprehensive pharmacological profiling in neuroblastoma cell lines using Deep Coverage Microscopy (DCM)

Sofia Zanotti, Marlies Verschuuren, Michael D. Hogarty, Kaat Durinck (UGent) , Suzanne Vanhauwaert (UGent) , Winnok H. De Vos and Franki Speleman (UGent)

(2019) RBSM Meeting 2019, Abstracts.
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Shallow whole genome sequencing on circulating cell-free DNA in pediatric cancer patients

Charlotte Vandeputte, Jolien Van Thorre, Ruben Van Paemel (UGent) , Andries De Koker (UGent) , Leen Willems (UGent) , Jo Van Dorpe (UGent) , Malaïka Van der Linden (UGent) , Jilke De Wilde (UGent) , Björn Menten (UGent) , L. van Zogchel, et al.

(2019) PEDIATRIC BLOOD & CANCER. 66. p.S505-S506
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PHF6loss drives IL7R oncogene addiction in TLX1 driven T-ALL

Siebe Loontiens (UGent) , Kaat Durinck (UGent) , Suzanne Vanhauwaert (UGent) , Lisa Depestel (UGent) , Mariana L Oliveira, Givani Dewyn (UGent) , Charles De Bock, Joao T Barata, David Langenau, Jan Cools, et al.

(2019) CANCER RESEARCH. 79(13, suppl.).
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17q gain provides proliferative advantage to human embryonic stem cells under replicative stress

Liselot Mus (UGent) , Stéphane Van Haver (UGent) , Geertrui Denecker (UGent) , Nadja Zeltner, Yudelca Ogando, Ellen Sanders (UGent) , Eva Jacobs, Mina Popovic, Christophe Van Neste (UGent) , Suzanne Vanhauwaert (UGent) , et al.

(2019) The DNA-damage response in cell physiology and disease, EMBO Workshop, Abstracts.
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17q gain provides proliferative advantage to human embryonic stem cells under conditions of replicative stress

Liselot Mus (UGent) , Geertrui Denecker (UGent) , Stéphane Van Haver (UGent) , Nadja Zeltner, Yudelca Ogando, Ellen Sanders (UGent) , Eva Jacobs, Mina Popovic, Christophe Van Neste (UGent) , Suzanne Vanhauwaert (UGent) , et al.

(2019) OncoPoint, 7th Research seminar, Abstracts.
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SOX11 is a key epigenetic regulator in the adrenergic MYCN amplified neuroblastoma

Amber Louwagie (UGent) , Bieke Decaesteker (UGent) , Carolina de Carvalho Nunes (UGent) , Geertrui Denecker (UGent) , Volodimir Olexiouk (UGent) , Karen Verboom, Moritz Gartlgruber, Wouter Van Loocke (UGent) , Elena Afanasyeva, Pauline Depuydt, et al.

(2019) OncoPoint, 7th Research seminar, Abstracts.
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SOX11 as mediator of the adrenergic cell state in NB

Bieke Decaesteker (UGent) , Amber Louwagie (UGent) , Sara De Brouwer (UGent) , Volodimir Olexiouk (UGent) , Geertrui Denecker (UGent) , Carolina de Carvalho Nunes (UGent) , Karen Verboom, Moritz Gartlgruber, Wouter Van Loocke (UGent) , Elena Afanasyeva, et al.

(2019) Pediatric Oncology and Hematology, 2nd KiTZ symposium, Abstracts.
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SOX11 is a key epigenetic regulator in the adrenergic MYCN amplified neuroblastoma

Amber Louwagie (UGent) , Bieke Decaesteker (UGent) , Sara De Brouwer (UGent) , Geertrui Denecker (UGent) , Carolina de Carvalho Nunes (UGent) , Volodimir Olexiouk (UGent) , Karen Verboom, Moritz Gartlgruber, Wouter Van Loocke (UGent) , Elena Afanasyeva, et al.

(2019) Belgian Society for Human Genetics, 19th Annual meeting, Abstracts.
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Purification of high-quality RNA from a small number of fluorescence activated cell sorted zebrafish cells for RNA sequencing purposes

Siebe Loontiens (UGent) , Lisa Depestel (UGent) , Suzanne Vanhauwaert (UGent) , Givani Dewyn (UGent) , Charlotte Gistelinck (UGent) , Karen Verboom, Wouter Van Loocke (UGent) , Filip Matthijssens (UGent) , Andy Willaert (UGent) , Jo Vandesompele (UGent) , et al.

(2019) BMC GENOMICS. 20.
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SMARTer single cell total RNA-sequencing

Karen Verboom, Celine Everaert (UGent) , Nathalie Bolduc, Kenneth Livak, Nurten Yigit (UGent) , Dries Rombaut, Jasper Anckaert (UGent) , Simon Lee, Morten Venø, Jørgen Kjems, et al.

(2019) NUCLEIC ACIDS RESEARCH. 47(16).
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Shallow whole genome sequencing on circulating cell-free DNA in pediatric cancer patients

Charlotte Vandeputte, Jolien Van Thorre, Ruben Van Paemel (UGent) , Andries De Koker (UGent) , Leen Willems (UGent) , Jo Van Dorpe (UGent) , Malaïka Van der Linden (UGent) , Jilke De Wilde (UGent) , Björn Menten (UGent) , Lieke van Zogchel, et al.

(2019) Belgian Society for Human Genetics, 19th Annual meeting, Abstracts.
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Shallow whole genome sequencing on circulating cell-free DNA in pediatric cancer patients

Charlotte Vandeputte, Jolien Van Thorre, Ruben Van Paemel (UGent) , Andries De Koker (UGent) , Leen Willems (UGent) , Jo Van Dorpe (UGent) , Malaïka Van der Linden (UGent) , Jilke De Wilde (UGent) , Björn Menten (UGent) , Lieke van Zogchel, et al.

(2019) OncoPoint, 7th Research seminar, Abstracts.
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- Conference Paper
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Successful copy number alteration profiling using circulating cell-free tumor DNA as a non-invasive alternative for tissue biopsies in pediatric cancer patients

Charlotte Vandeputte, Jolien Van Thorre, Ruben Van Paemel (UGent) , Andries De Koker (UGent) , Leen Willems (UGent) , Jo Van Dorpe (UGent) , Malaïka Van der Linden (UGent) , Jilke De Wilde (UGent) , Björn Menten (UGent) , Lieke van Zogchel, et al.

(2019) cell free DNA, 3de Nederlandse dag, Abstracts.
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Pinpointing a potential role for CLEC12B in cancer predisposition through familial exome sequencing

Charlotte Derpoorter (UGent) , Karl Vandepoele (UGent) , Araceli Diez Fraile, Katrien Vandemeulebroecke (UGent) , Bram De Wilde (UGent) , Franki Speleman (UGent) , Nadine Van Roy (UGent) , Tim Lammens (UGent) and Genevieve Laureys (UGent)

(2019) PEDIATRIC BLOOD & CANCER. 66(2).
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- A1
- open access
Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes

Dries Rombaut, Hua-Sheng Chiu, Bieke Decaesteker (UGent) , Celine Everaert (UGent) , Nurten Yigit (UGent) , Agathe Pelthier, Isabelle Janoueix, Christophe Bartenhagen, Matthias Fischer, Stephen Roberts, et al.

(2019) SCIENTIFIC REPORTS. 9.
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Long noncoding RNA expression profiling in cancer : challenges and opportunities

Lucia Lorenzi, Francisco Avila Cobos (UGent) , Anneleen Decock (UGent) , Celine Everaert (UGent) , Hetty Helsmoortel (UGent) , Steve Lefever (UGent) , Karen Verboom, Pieter-Jan Volders (UGent) , Franki Speleman (UGent) , Jo Vandesompele (UGent) , et al.

(2019) GENES CHROMOSOMES & CANCER. 58(4). p.191-199
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Exploring the contribution of gene dosage effects of 17q gain genes on hESC and neuroblastoma proliferation

Liselot Mus (UGent) , Geertrui Denecker (UGent) , Stéphane Van Haver (UGent) , Nadja Zeltner, Yudelca Ogando, Ellen Sanders (UGent) , Eva Jacobs, Mina Popovic, Christophe Van Neste (UGent) , Suzanne Vanhauwaert (UGent) , et al.

(2019) Pediatric Oncology and Hematology, 2nd KiTZ symposium, Abstracts.
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- C3
- open access
SMARTer single cell total RNA sequencing

Karen Verboom, Celine Everaert (UGent) , Nathalie Bolduc, Kenneth Livak, Nurten Yigit (UGent) , Dries Rombaut, Jasper Anckaert (UGent) , Morten Venø, Jørgen Kjems, Franki Speleman (UGent) , et al.

(2019) Single Cell Biology, Keystone symposium, Abstracts.
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- Journal Article
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ALK positively regulates MYCN activity through repression of HBP1 expression

Shana Claeys (UGent) , Geertrui Denecker (UGent) , Kaat Durinck (UGent) , Bieke Decaesteker (UGent) , Liselot Mus (UGent) , Siebe Loontiens (UGent) , Suzanne Vanhauwaert (UGent) , Kristina Althoff, Caroline Wigerup, Daniel Bexell, et al.

(2019) ONCOGENE. 38(5). p.2690-2705
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- A2
DREAM target reactivation by core transcriptional regulators supports neuroblastoma growth

Bieke Decaesteker (UGent) , Katleen De Preter (UGent) and Franki Speleman (UGent)

(2019) MOLECULAR & CELLULAR ONCOLOGY. 6(2).
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- Journal Article
- A2
Zebravis als in-vivo model voor de studie van acute lymfatische leukemie

Siebe Loontiens (UGent) , Suzanne Vanhauwaert (UGent) , Lisa Depestel (UGent) , Kaat Durinck (UGent) and Franki Speleman (UGent)

(2019) ONCOHEMATO. 13(3). p.11-17
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Epigenetic regulation of neuroblastoma development

Kaat Durinck (UGent) and Franki Speleman (UGent)

(2018) CELL AND TISSUE RESEARCH. 372(2). p.309-324
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Cell of origin dictates aggression and stem cell number in acute lymphoblastic leukemia

Elaine G Garcia, Sowmya Iyer, Sara P Garcia, Siebe Loontiens (UGent) , Ruslan I Sadreyev, Franki Speleman (UGent) and David M Langenau

(2018) LEUKEMIA. 32(8). p.1860-1865
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Network modeling of microRNA-mRNA interactions in neuroblastoma tumorigenesis identifies miR-204 as a direct inhibitor of MYCN

Chi Yan Ooi, Daniel R Carter, Bing Liu, Chelsea Mayoh, Anneleen Beckers (UGent) , Amit Lalwani, Zsuzsanna Nagy, Sara De Brouwer (UGent) , Bieke Decaesteker (UGent) , Tzong-Tyng Hung, et al.

(2018) CANCER RESEARCH. 78(12). p.3122-3034
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The RRM2-PHF6 complex protects neuroblastoma cells from DNA damage accumulation to install a replication stress resistance phenotype

Carolina de Carvalho Nunes (UGent) , Kaat Durinck (UGent) , Lisa Depestel (UGent) , Siebe Loontiens (UGent) , Louis Delhaye (UGent) , Sofia Zanotti, Emmy Dolman, Aline Eggermont (UGent) , Bieke Decaesteker (UGent) , Pauline Depuydt, et al.

(2018) Advances in Neuroblastoma Research, Congress abstracts.
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The core regulatory circuit component TBX2 is implicated in cell cycle control and proliferation in neuroblastoma

Bieke Decaesteker (UGent) , Geertrui Denecker (UGent) , Wouter Van Loocke, Moritz Gartlgruber, Pauline Depuydt, Fanny De Vloed (UGent) , Shana Claeys (UGent) , Dries Rombaut, Siebe Loontiens (UGent) , Anton Henssen, et al.

(2018) OncoPoint, 6th Research seminar, Abstracts.
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- Conference Paper
- C3
SOX11 is a transcriptional circuit dosage sensitive transcription factor controlling SWI/SNF components

Bieke Decaesteker (UGent) , Sara De Brouwer (UGent) , Geertrui Denecker (UGent) , Fanny De Vloed (UGent) , Wouter Van Loocke (UGent) , Suzanne Vanhauwaert (UGent) , Pauline Depuydt, Moritz Gartlgruber, Jolien De Wyn, Genevieve Laureys, et al.

(2018) Advances in Neuroblastoma Research, Congress abstracts.
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- Conference Paper
- C3
The core regulatory circuit component TBX2 is implicated in cell cycle control and proliferation in neuroblastoma

Bieke Decaesteker (UGent) , Geertrui Denecker (UGent) , Christophe Van Neste (UGent) , Fanny De Vloed (UGent) , Moritz Gartlgruber, Pauline Depuydt, Wouter Van Loocke (UGent) , Shana Claeys (UGent) , Dries Rombaut, Siebe Loontiens (UGent) , et al.

(2018) Advances in Neuroblastoma Research, Congress abstracts.
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TBX2 is implicated in cell cycle control and proliferation in neuroblastoma

Bieke Decaesteker (UGent) , Geertrui Denecker (UGent) , Christophe Van Neste (UGent) , Fanny De Vloed (UGent) , Moritz Gartlgruber, Pauline Depuydt, Wouter Van Loocke (UGent) , Shana Claeys (UGent) , Dries Rombaut, Siebe Loontiens (UGent) , et al.

(2018) Belgian Society for Human Genetics, 18th Annual meeting, Abstracts.
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- A1
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TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets

Bieke Decaesteker (UGent) , Geertrui Denecker (UGent) , Christophe Van Neste (UGent) , Emmy M Dolman, Wouter Van Loocke (UGent) , Moritz Gartlgruber, Carolina de Carvalho Nunes (UGent) , Fanny De Vloed (UGent) , Pauline Depuydt, Karen Verboom, et al.

(2018) NATURE COMMUNICATIONS. 9.
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- A1
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Expressed repetitive elements are broadly applicable reference targets for normalization of reverse transcription-qPCR data in mice

Marjolijn Renard (UGent) , Suzanne Vanhauwaert (UGent) , Marine Vanhomwegen (UGent) , Ali Rihani, Niels Vandamme (UGent) , Steven Goossens (UGent) , Geert Berx (UGent) , Pieter Van Vlierberghe (UGent) , Jody J Haigh, Bieke Decaesteker (UGent) , et al.

(2018) SCIENTIFIC REPORTS. 8.
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In silico discovery of a FOXM1 driven embryonal signaling pathway in therapy resistant neuroblastoma tumors

Suzanne Vanhauwaert (UGent) , Bieke Decaesteker (UGent) , Sara De Brouwer (UGent) , Carina Leonelli (UGent) , Kaat Durinck (UGent) , Pieter Mestdagh (UGent) , Jo Vandesompele (UGent) , Karen Sermon, Geertrui Denecker (UGent) , Christophe Van Neste (UGent) , et al.

(2018) SCIENTIFIC REPORTS. 8.
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LDHA in neuroblastoma is associated with poor outcome and its depletion decreases neuroblastoma growth independent of aerobic glycolysis

Carmen Dorneburg, Matthias Fischer, Thomas FE Barth, Wolfgang Mueller-Klieser, Barbara Hero, Judith Gecht, Daniel R Carter, Katleen De Preter (UGent) , Benjamin Mayer, Lisa Christner, et al.

(2018) CLINICAL CANCER RESEARCH. 24(22). p.5772-5783
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A high-throughput 3’ UTR reporter screening identifies microRNA interactomes of cancer genes

Gert Van Peer (UGent) , Evelien Mets (UGent) , Shana Claeys (UGent) , Ines De Punt (UGent) , Steve Lefever (UGent) , Maté Ongenaert (UGent) , Pieter Rondou (UGent) , Franki Speleman (UGent) , Pieter Mestdagh (UGent) and Jo Vandesompele (UGent)

(2018) PLOS ONE. 13(3).
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Promoter-associated proteins of EPAS1 identified by enChIP-MS : a putative role of HDX as a negative regulator

Arash Hamidian, Marica Vaapil, Kristoffer von Stedingk, Toshitsugu Fujita, Camilla U Persson, Pontus Eriksson, Srinivas Veerla, Katleen De Preter (UGent) , Franki Speleman (UGent) , Hodaka Fujii, et al.

(2018) BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 499(2). p.291-298
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Exploring the contribution of gene dosage effects of 17q gain on ESC and neuroblastoma proliferation

Liselot Mus (UGent) , Geertrui Denecker (UGent) , Nadja Zeltner, Yudelca Ogando, Stéphane Van Haver (UGent) , Ellen Sanders (UGent) , Eva Jacobs, Mina Popovic, Christophe Van Neste (UGent) , Suzanne Vanhauwaert (UGent) , et al.

(2018) Belgian Society for Human Genetics, 18th Annual meeting, Abstracts.
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- C3
Exploring the contribution of gene dosage effects of 17Q gain on ESC and neuroblastoma proliferation

Liselot Mus (UGent) , Geertrui Denecker (UGent) , Nadja Zeltner, Yudelca Ogando, Stéphane Van Haver (UGent) , Ellen Sanders (UGent) , Eva Jacobs, Mina Popovic, Christophe Van Neste (UGent) , Suzanne Vanhauwaert (UGent) , et al.

(2018) OncoPoint, 6th Research seminar, Abstracts.
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- C3
- open access
Exploring the contribution of gene dosage effects of 17q gain on ESC and neuroblastoma proliferation

Liselot Mus (UGent) , Geertrui Denecker (UGent) , Nadja Zeltner, Yudelca Ogando, Stéphane Van Haver (UGent) , Ellen Sanders (UGent) , Eva Jacobs, Mina Popovic, Christophe Van Neste (UGent) , Suzanne Vanhauwaert (UGent) , et al.

(2018) Advances in Neuroblastoma Research, Congress abstracts.
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- A1
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A comprehensive inventory of TLX1 controlled long non-coding RNAs in T-cell acute lymphoblastic leukemia through polyA+ and total RNA sequencing

Karen Verboom, Wouter Van Loocke (UGent) , Pieter-Jan Volders (UGent) , Bieke Decaesteker (UGent) , Francisco Avila Cobos (UGent) , Simon Bornschein, Charles E de Bock, Zeynep Kalender Atak, Emmanuelle Clappier, Stein Aerts, et al.

(2018) HAEMATOLOGICA. 103(12). p.E585-E589
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Non-invasive differential diagnosis of neuroblastoma with other paediatric solid tumors using methylation profiling of circulating cell-free DNA

Ruben Van Paemel (UGent) , Anneleen Decock (UGent) , Charlotte Vandeputte, Tim Lammens (UGent) , Genevieve Laureys (UGent) , Franki Speleman (UGent) , Wim Van Criekinge (UGent) , Nadine Van Roy (UGent) , Jo Vandesompele (UGent) , Katleen De Preter (UGent) , et al.

(2018) Advances in Neuroblastoma Research, Congress abstracts.
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- C3
Isolation of high-quality RNA from fluorescent activated cell sorted (FACS) zebrafish cells for RNA sequencing purposes

Siebe Loontiens (UGent) , Suzanne Vanhauwaert (UGent) , Lisa Depestel (UGent) , Givani Dewyn (UGent) , Charlotte Gistelinck (UGent) , Karen Verboom, Els Janssens (UGent) , Filip Matthijssens (UGent) , Andy Willaert (UGent) , Jo Vandesompele (UGent) , et al.

(2018) the 11th Zebrafish Disease Models Conference, Abstracts.
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Scrutinizing PHF6 regulatory networks in T-ALL and normal hematopoiesis using zebrafish

Siebe Loontiens (UGent) , Kaat Durinck (UGent) , Inge Van de Walle (UGent) , Finola Moore, Suzanne Vanhauwaert (UGent) , Els Janssens (UGent) , Givani Dewyn (UGent) , Lisa Depestel (UGent) , Christophe Van Neste (UGent) , David Langenau, et al.

(2018) BeSHG meeting 2017, Abstracts.
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Comprehensive pharmacological profiling in neuroblastoma cell lines using Deep Coverage Microscopy (DCM)

Sofia Zanotti, Marlies Verschuuren, Kaat Durinck (UGent) , Franki Speleman (UGent) and Winnok De Vos

(2018) Belgian Society for Human Genetics, 18th Annual meeting, Abstracts.
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- C3
Comprehensive pharmacological profiling in neuroblastoma cell lines using Deep Coverage Microscopy (DCM)

Sofia Zanotti, Marlies Verschuuren, Kaat Durinck (UGent) , Franki Speleman (UGent) and Winnok De Vos

(2018) DNA replication : from basic biology to disease, EMBO / EMBL symposium, Abstracts.
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MYCN activation in hTERT immortalized RPE cells as a model for oncogene induced senescence

Sofia Zanotti, Marlies Verschuuren, Michael D Hogarty, Kaat Durinck (UGent) , Winnok De Vos and Franki Speleman (UGent)

(2018) Joint BSCDB/RBSM meeting: advanced microscopy in cell and development biology, Antwerpen.
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MYCN activation in hTERT immortalized RPE cells as model for oncogene induced senescence

Sofia Zanotti, Bieke Decaesteker (UGent) , Marlies Verschuuren, Michael D Hogarty, Kaat Durinck (UGent) , Winnok De Vos and Franki Speleman (UGent)

(2018) PhD research day, Abstracts.
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Shallow whole genome sequencing allows successful copy number profiling in formalin-fixed paraffin-embedded material in neuroblastoma patients

Charlotte Vandeputte, Ruben Van Paemel (UGent) , Bram De Wilde (UGent) , Malaïka Van der Linden (UGent) , Jo Van Dorpe (UGent) , Björn Menten (UGent) , Franki Speleman (UGent) , Nadine Van Roy (UGent) and Katleen De Preter (UGent)

(2018) Advances in Neuroblastoma Research, Congress abstracts.
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A mechanistic classification of clinical phenotypes in neuroblastoma.

Sandra Ackermann, Maria Cartolano, Barbara Hero, Anne Welte, Yvonne Kahlert, Andrea Roderwieser, Christoph Bartenhagen, Esther Walter, Judith Gecht, Laura Kerschke, et al.

(2018) SCIENCE. 362(6419). p.1165-1170
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A mechanistic classification of clinical phenotypes in neuroblastoma

S Ackermann, M Cartolano, B Hero, A Roderwieser, C Bartenhagen, C Rosswog, F Hertwig, T Simon, A Eggert, Franki Speleman (UGent) , et al.

(2018) PEDIATRIC BLOOD & CANCER. 65(suppl. 2). p.S234-S234
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A mechanistic classification of clinical phenotypes in neuroblastoma

S Ackermann, M Cartolano, B Hero, A Roderwieser, C Bartenhagen, C Rosswog, F Hertwig, T Simon, A Eggert, Franki Speleman (UGent) , et al.

(2018) PEDIATRIC BLOOD & CANCER. 65(suppl. 2). p.S87-S88
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LDHA predicts poor survival in neuroblastoma and its depletion causes aerobic glycolysis-independent inhibition of neuroblastoma cells

C Dorneburg, M Fischer, TFE Barth, W Mueller-Klieser, B Hero, J Gecht, DR Carter, Katleen De Preter (UGent) , Franki Speleman (UGent) , GM Marshall, et al.

(2018) PEDIATRIC BLOOD & CANCER. 65(suppl. 2). p.S238-S238
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Exploring the contribution of gene dosage effects of 17q gain genes on hESC and neuroblastoma proliferation

Liselot Mus (UGent) , Geertrui Denecker (UGent) , Stéphane Van Haver (UGent) , Nadja Zeltner, Yudelca Ogando, Ellen Sanders (UGent) , Eva Jacobs, Mina Popovic, Christophe Van Neste (UGent) , Suzanne Vanhauwaert (UGent) , et al.

(2018) Belgian Society for Stem Cell Research, 5th Annual meeting, Abstracts.
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Circulating microRNA biomarkers for metastatic disease in neuroblastoma patients

Fjoralba Zeka (UGent) , Anneleen Decock (UGent) , Alan Van Goethem (UGent) , Katrien Vanderheyden, Fleur Demuynck (UGent) , Tim Lammens (UGent) , Hetty Helsmoortel (UGent) , Joëlle Vermeulen, Rosa Noguera, Ana P. Berbegall, et al.

(2018) JCI INSIGHT. 3(23).
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Longitudinal evaluation of murine serum microRNAs as biomarkers for neuroblastoma burden and therapeutic TP53 reactivation

Alan Van Goethem (UGent) , Nurten Yigit (UGent) , Celine Everaert (UGent) , Myrthala Moreno-Smith, Sanjeev A Vasudevan, Fjoralba Zeka (UGent) , Fleur Demunck, Eveline Barbieri, Franki Speleman (UGent) , Pieter Mestdagh (UGent) , et al.

(2018) Advances in Neuroblastoma Research, Congress abstracts.
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Circulating microRNA biomarkers for metastatic neuroblastoma

Fjoralba Zeka (UGent) , Alan Van Goethem (UGent) , Tim Lammens (UGent) , Anneleen Decock (UGent) , Hetty Helsmoortel (UGent) , Genevieve Laureys (UGent) , Michael Hogarty, Eveline Barbieri, Jason Shohet, Frank Berthold, et al.

(2018) Advances in Neuroblastoma Research, Congress abstracts.
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Integrated proximal proteomics reveals IRS2 as a determinant of cell survival in ALK-driven neuroblastoma

Kristina B Emdal, Anna-Kathrine Pedersen, Dorte B Bekker-Jensen, Alicia Lundby, Shana Claeys (UGent) , Katleen De Preter (UGent) , Franki Speleman (UGent) , Chiara Francavilla and Jesper V Olsen

(2018) SCIENCE SIGNALING. 11(557).
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Data Descriptor: Meta-mining of copy number profiles of high-risk neuroblastoma tumors

Pauline Depuydt, J Koster, V Boeva, TD Hocking, Franki Speleman (UGent) , G Schleiermacher and Katleen De Preter (UGent)

(2018) SCIENTIFIC DATA. 5.

HTSplotter : an end-to-end data processing, analysis and visualisation tool for chemical and genetic in vitro perturbation screening

MYCN and SNRPD3 cooperate to maintain a balance of alternative splicing events that drives neuroblastoma progression

Preclinical exploration of the DNA damage response pathway using the interactive neuroblastoma cell line explorer CLEAN

Human iPSC modeling recapitulates in vivo sympathoadrenal development and reveals an aberrant developmental subpopulation in familial neuroblastoma

Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma

Mitotic dysregulation at tumor initiation creates a therapeutic vulnerability to combination anti-mitotic and pro-apoptotic agents for MYCN-driven neuroblastoma

Exploration of neuroblastoma xenograft models for tumor extracellular RNA profiling in murine blood plasma

Exploration of neuroblastoma xenograft models for the analysis of tumoral cell-free RNA in murine blood plasma

Longitudinal evaluation of serum microRNAs as biomarkers for neuroblastoma burden and therapeutic p53 reactivation

A harmonized single-cell transcriptomic atlas of human neuroblastoma

Whole transcriptome profiling of liquid biopsies from tumour xenografted mouse models enables specific monitoring of tumour-derived extracellular RNA

SOX11 regulates SWI/SNF complex components as member of the adrenergic neuroblastoma core regulatory circuitry

Exploration of neuroblastoma xenograft models for tumor extracellular RNA profiling in murine blood plasma

Complementarity of single-nucleus and single-cell RNA sequencing to study the transcriptional heterogeneity of neuroblastoma tumors

Complementarity of single-nucleus and single-cell RNA sequencing to study the transcriptional heterogeneity of neuroblastoma tumors

Cellular senescence in neuroblastoma

HTSplotter : an end-to-end data processing, analysis and visualisation tool for chemical and genetic in vitro perturbation screening

RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition

The adrenergic-specific long non-coding RNA NESPR controls survival of neuroblastoma cells

RRM2 enhances MYCN driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition

The feasibility of using liquid biopsies as a complementary assay for copy number aberration profiling in routinely collected paediatric cancer patient samples

Whole transcriptome profiling of liquid biopsies from tumour xenografted mouse models enables specific monitoring of tumour-derived extracellular RNA

Exploration of neuroblastoma xenograft models for tumor extracellular RNA profiling in murine blood plasma

Whole transcriptome profiling of liquid biopsies from tumour xenografted mouse models enables specific monitoring of tumour-derived extracellular RNA

From DNA copy number gains and tumor dependencies to novel therapeutic targets for high-risk neuroblastoma

A G316A polymorphism in the ornithine decarboxylase gene promoter modulates MYCN-driven childhood neuroblastoma

Kalirin-RAC controls nucleokinetic migration in ADRN-type neuroblastoma

SOX11 as guardian of epigenetic plasticity in neuroblastoma

MYCN-induced nucleolar stress drives an early senescence-like transcriptional program in hTERT-immortalized RPE cells

PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis

Recurrent chromosomal imbalances provide selective advantage to human embryonic stem cells under enhanced replicative stress conditions

The functional annotation and exploration the SOX11 enhanceosome

MEIS2 is an adrenergic core regulatory transcription factor involved in early initiation of TH-MYCN-driven neuroblastoma formation

Accelerating drug development for neuroblastoma : summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma

SOX11 as guardian of epigenetic plasticity in neuroblastoma

A novel TLX1-driven T-ALL zebrafish model : comparative genomic analysis with other leukemia models

Large-scale circular RNA deregulation in T-ALL : unlocking unique ectopic expression of molecular subtypes

Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development

PHF6 expression levels impact human hematopoietic stem cell differentiation

The ETS transcription factor ETV5 is a target of activated ALK in neuroblastoma contributing to increased tumour aggressiveness

The pitfalls and promise of liquid biopsies for diagnosing and treating solid tumors in children : a review

Long noncoding RNA SILC1 is an upstream regulator of SOX11 in neuroblastoma

MYCN activation in hTERT immortalized RPE cells as model for oncogene induced senescence

Comprehensive pharmacological profiling in neuroblastoma cell lines using Deep Coverage Microscopy (DCM)

Shallow whole genome sequencing on circulating cell-free DNA in pediatric cancer patients

PHF6loss drives IL7R oncogene addiction in TLX1 driven T-ALL

17q gain provides proliferative advantage to human embryonic stem cells under replicative stress

17q gain provides proliferative advantage to human embryonic stem cells under conditions of replicative stress

SOX11 is a key epigenetic regulator in the adrenergic MYCN amplified neuroblastoma

SOX11 as mediator of the adrenergic cell state in NB

SOX11 is a key epigenetic regulator in the adrenergic MYCN amplified neuroblastoma

Purification of high-quality RNA from a small number of fluorescence activated cell sorted zebrafish cells for RNA sequencing purposes

SMARTer single cell total RNA-sequencing

Shallow whole genome sequencing on circulating cell-free DNA in pediatric cancer patients

Shallow whole genome sequencing on circulating cell-free DNA in pediatric cancer patients

Successful copy number alteration profiling using circulating cell-free tumor DNA as a non-invasive alternative for tissue biopsies in pediatric cancer patients

Pinpointing a potential role for CLEC12B in cancer predisposition through familial exome sequencing

Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes

Long noncoding RNA expression profiling in cancer : challenges and opportunities

Exploring the contribution of gene dosage effects of 17q gain genes on hESC and neuroblastoma proliferation

SMARTer single cell total RNA sequencing

ALK positively regulates MYCN activity through repression of HBP1 expression

DREAM target reactivation by core transcriptional regulators supports neuroblastoma growth

Zebravis als in-vivo model voor de studie van acute lymfatische leukemie

Epigenetic regulation of neuroblastoma development

Cell of origin dictates aggression and stem cell number in acute lymphoblastic leukemia

Network modeling of microRNA-mRNA interactions in neuroblastoma tumorigenesis identifies miR-204 as a direct inhibitor of MYCN

The RRM2-PHF6 complex protects neuroblastoma cells from DNA damage accumulation to install a replication stress resistance phenotype

The core regulatory circuit component TBX2 is implicated in cell cycle control and proliferation in neuroblastoma

SOX11 is a transcriptional circuit dosage sensitive transcription factor controlling SWI/SNF components

The core regulatory circuit component TBX2 is implicated in cell cycle control and proliferation in neuroblastoma

TBX2 is implicated in cell cycle control and proliferation in neuroblastoma

TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets

Expressed repetitive elements are broadly applicable reference targets for normalization of reverse transcription-qPCR data in mice

In silico discovery of a FOXM1 driven embryonal signaling pathway in therapy resistant neuroblastoma tumors

LDHA in neuroblastoma is associated with poor outcome and its depletion decreases neuroblastoma growth independent of aerobic glycolysis

A high-throughput 3’ UTR reporter screening identifies microRNA interactomes of cancer genes

Promoter-associated proteins of EPAS1 identified by enChIP-MS : a putative role of HDX as a negative regulator

Exploring the contribution of gene dosage effects of 17q gain on ESC and neuroblastoma proliferation

Exploring the contribution of gene dosage effects of 17Q gain on ESC and neuroblastoma proliferation