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Osteopontin characterizes bile duct-associated macrophages and correlates with liver fibrosis severity in primary sclerosing cholangitis
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Network analysis of large-scale ImmGen and Tabula Muris datasets highlights metabolic diversity of tissue mononuclear phagocytes
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Studying macrophages in the murine steatotic liver using flow cytometry and confocal microscopy
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- Journal Article
- A1
- open access
A20 is a master switch of IL-33 signalling in macrophages and determines IL-33-induced lung immunity
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- Journal Article
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Limitations of PLX3397 as a microglial investigational tool : peripheral and off-target effects dictate the response to inflammation
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Kupffer cells contested as early drivers in the pathogenesis of primary sclerosing cholangitis
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Transient Kupffer cell depletion and subsequent replacement by infiltrating monocyte-derived cells does not alter the induction or progression of hepatocellular carcinoma
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Complementarity of single-nucleus and single-cell RNA sequencing to study the transcriptional heterogeneity of neuroblastoma tumors
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- Journal Article
- A1
- open access
Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches
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Who on IRF are you? IRF8 deficiency redirects cDC1 lineage commitment
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Modulating hepatic macrophages with annexin A1 in non-alcoholic steatohepatitis
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- Journal Article
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- open access
Liver macrophages in health and disease
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- Miscellaneous
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A breath of fresh macrophages ameliorates inflammation in the hypoxic lung
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Complementarity of single-nucleus and single-cell RNA sequencing to study the transcriptional heterogeneity of neuroblastoma tumors
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Single-cell RNA and protein profiling of immune cells from the mouse brain and its border tissues
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- Journal Article
- A1
- open access
Hepatic macrophage responses in inflammation, a function of plasticity, heterogeneity or both?
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Welcoming c-MAF to the macrophage transcription factor VAM-ily
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In matters of the heart, (cellular) communication is key
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- Journal Article
- A1
- open access
ILC3s control splenic cDC homeostasis via lymphotoxin signaling
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- Journal Article
- A1
- open access
A20 deficiency in myeloid cells protects mice from diet-induced obesity and insulin resistance due to increased fatty acid metabolism
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The conventional dendritic cell lineage is born
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ImmGen at 15
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- Journal Article
- A1
- open access
Hepatic PPARα function and lipid metabolic pathways are dysregulated in polymicrobial sepsis
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- Journal Article
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Macrophage subsets in obesity, aligning the liver and adipose tissue
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- Journal Article
- A1
- open access
Transcriptional regulation of DC fate specification
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Inflammatory type 2 cDCs acquire features of cDC1s and macrophages to orchestrate immunity to respiratory virus infection
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- Journal Article
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- open access
Osteopontin expression identifies a subset of recruited macrophages distinct from Kupffer cells in the fatty liver
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Deep learning of immune cell differentiation
(2020) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 117(41). p.25655-25666 -
- Journal Article
- A1
- open access
OTULIN prevents liver inflammation and hepatocellular carcinoma by inhibiting FADD- and RIPK1 kinase-mediated hepatocyte apoptosis
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- Journal Article
- A1
- open access
Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury
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- Journal Article
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Stellate cells, hepatocytes, and endothelial cells imprint the Kupffer cell identity on monocytes colonizing the liver macrophage niche
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- Journal Article
- A1
- open access
ZEBs : novel players in immune cell development and function
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Priority lane to cDC1 open for IRF8⁺ progenitors
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A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment
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- Journal Article
- A1
- open access
A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation
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The role of Kupffer cells in hepatic iron and lipid metabolism
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Tissue unit-ed : lung cells team up to drive alveolar macrophage development
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- Journal Article
- A1
- open access
Myocarditis elicits dendritic cell and monocyte infiltration in the heart and self-antigen presentation by conventional type 2 dendritic cells
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- Journal Article
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- open access
Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens
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- Journal Article
- A1
- open access
The transcription factor ZEB2 is required to maintain the tissue-specific identities of macrophages
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'NOTCHing up' the in vitro production of dendritic cells
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- Journal Article
- A1
- open access
Macrophages and lipid metabolism
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Does niche competition determine the origin of tissue-resident macrophages?
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Barrier-tissue macrophages : functional adaptation to environmental challenges
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Kupffer cell pool is maintained by local proliferation and the differentiation of bone marrow monocytes into short-lived monocyte-derived Kupffer cells during non-alcoholic steatohepatitis and recovery
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Non-alcoholic steatohepatitis induces transient changes within the liver macrophage pool
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- Journal Article
- A1
- open access
TGFβR signalling controls CD103⁺CD11b⁺ dendritic cell development in the intestine
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- Journal Article
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- open access
Myocardial infarction primes autoreactive T cells through activation of dendritic cells
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Development of conventional dendritic cells : from common bone marrow progenitors to multiple subsets in peripheral tissues
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Isolation and identification of intestinal myeloid cells
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- Journal Article
- A1
- open access
The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2
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Yolk sac macrophages, fetal liver, and adult monocytes can colonize an empty niche and develop into functional tissue-resident macrophages
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- Journal Article
- A1
- open access
The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity
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Conventional dendritic cells : identification, subsets, development, and functions
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- Journal Article
- A1
- open access
Long-lived self-renewing bone marrow-derived macrophages displace embryo-derived cells to inhabit adult serous cavities
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- Journal Article
- A1
- open access
Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells
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- Journal Article
- A1
- open access
Unsupervised high-dimensional analysis aligns dendritic cells across tissues and species
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IRF8 transcription factor controls survival and function of terminally differentiated conventional and plasmacytoid dendritic cells, respectively
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Isolation and identification of conventional dendritic cell subsets from the intestine of mice and men
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- Journal Article
- A1
- open access
Lymph-borne CD8 alpha(+) dendritic cells are uniquely able to cross-prime CD8(+) T cells with antigen acquired from intestinal epithelial cells
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- Journal Article
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- open access
CCR2⁺CD103⁻ intestinal dendritic cells develop from DC-committed precursors and induce interleukin-17 production by T cells
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Type 2 Innate Lymphoid Cells Drive CD4(+) Th2 Cell Responses
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Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice
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Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid
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- Journal Article
- A1
- open access
The MacBlue binary transgene (csf1r-gal4VP16/UAS-ECFP) provides a novel marker for visualisation of subsets of monocytes, macrophages and dendritic cells and responsiveness to CSF1 administration
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- Journal Article
- A1
- open access
Signal regulatory protein alpha (SIRPα) regulates the homeostasis of CD103⁺CD11b⁺ DCs in the intestinal lamina propria
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Mononuclear phagocytes of the intestine, the skin, and the lung
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- Journal Article
- A1
- open access
Dendritic cell subsets in the intestinal lamina propria : ontogeny and function
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Intestinal CD103(-) dendritic cells migrate in lymph and prime effector T cells
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- Journal Article
- A1
- open access
Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6C(hi) monocyte precursors
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Intestinal CD103(+) dendritic cells : master regulators of tolerance?