Ghent University Academic Bibliography

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Evaluation of an epigenetic assay for predicting repeat prostate biopsy outcome in African American men

Robert L, Jr Waterhouse, Leander Van Neste, Kelvin A Moses, Carlton Barnswell, Jonathan L Silberstein, Mark Jalkut, Ronald Tutrone, James Sylora, Ronald Anglade, Myron Murdock, et al.

(2019) UROLOGY. 128. p.62-65
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Analysis of DNA methylation in cancer : location revisited

Alexander Koch, Sophie C Joosten, Zheng Feng, Tim C de Ruijter, Muriel X Draht, Veerle Melotte, Kim M Smits, Jurgen Veeck, James G Herman, Leander Van Neste, et al.

(2018) NATURE REVIEWS CLINICAL ONCOLOGY. 15(7). p.459-466
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Cost-effectiveness of a new urinary biomarker-based risk score compared to standard of care in prostate cancer diagnostics : a decision analytical model

Siebren Dijkstra, Tim M Govers, Rianne J Hendriks, Jack A Schalken, Wim Van Criekinge (UGent) , Leander Van Neste, Janneke PC Grutters, John P Michiel Sedelaar and Inge M van Oort

(2017) BJU INTERNATIONAL. 120(5). p.659-665
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- Journal Article
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Epigenetic risk score improves prostate cancer risk assessment

Leander Van Neste, Jack Groskopf, William E Grizzle, George W Adams, Mark S DeGuenther, Peter N Kolettis, James E Bryant, Gary P Kearney, Michael C Kearney, Wim Van Criekinge (UGent) , et al.

(2017) PROSTATE. 77(12). p.1259-1264
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- Conference Paper
- C3
Clinical performance of an epigenetic assay to identify occult high-grade prostate cancer in African American men

Leander Van Neste, Carlton Barnswell, Mark Jalkut, Ronald Tutrone, James Sylora, Ronald Anglade, Myron Murdock, Kelvin A Moses, Zvi Shiffman, Todd Vandenberg, et al.

(2017) JOURNAL OF UROLOGY. 197(4, suppl.). p.E128-E128
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- Journal Article
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A four-gene promoter methylation marker panel consisting of GREM1, NEURL, LAD1, and NEFH predicts survival of clear cell renal cell cancer patients

Iris JH van Vlodrop, Sophie C Joosten, Tim De Meyer (UGent) , Kim M Smits, Leander Van Neste (UGent) , Veerle Melotte, Marcella MLL Baldewijns, Leo J Schouten, Piet A van den Brandt, Jana Jeschke, et al.

(2017) CLINICAL CANCER RESEARCH. 23(8). p.2006-2018
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- Journal Article
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Evaluation of an epigenetic profile for the detection of bladder cancer in patients with hematuria

Kim EM van Kessel, Leander Van Neste, Irene Lurkin, Ellen C Zwarthoff and Wim Van Criekinge (UGent)

(2016) JOURNAL OF UROLOGY. 195(3). p.601-607
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- Conference Paper
- C3
Identification of high-grade prostate cancer using urine-based molecular biomarkers combined with clinical risk factors

Leander Van Neste, Geert Trooskens (UGent) , Rianne J Hendriks, Jack Schalken and Wim Van Criekinge (UGent)

(2016) JOURNAL OF UROLOGY. 195(4, suppl.). p.E698-E698
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Risk score predicts high-grade prostate cancer in DNA-methylation positive, histopathologically negative biopsies

Leander Van Neste, Alan W Partin, Grant D Stewart, Jonathan I Epstein, David J Harrison and Wim Van Criekinge (UGent)

(2016) PROSTATE. 76(12). p.1078-1087
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- Conference Paper
- C3
Clinical utility of an epigenetic assay to reduce unnecessary repeat prostate biopsies

Jason Hafron, Thanh Huynh, Ayad S Khourdaji, Richard D Sante, Wim Van Criekinge (UGent) and Leander Van Neste

(2016) JOURNAL OF UROLOGY. 195(4, suppl.). p.E544-E544
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- Conference Paper
- C3
Ability of an epigenetic assay to identify anterior prostate tumors based on a negative 12-core biopsy

Todd Matthew Morgan, Simpa Samuel Salami, John Thomas Wei, Ganesh S Palapattu, Amy Gursky, Wim Van Criekinge (UGent) , Leander Van Neste and Rohit Mehra

(2016) JOURNAL OF CLINICAL ONCOLOGY. 34(2, suppl.).
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- Conference Paper
- C3
Combined DNA-methylation intensity and clinical risk score to stratify patients for high-grade disease

Leander Van Neste, Grant Stewart, Sandra Marlene Gaston, William E Grizzle, George W Adams, Gary P Kearney, Jonathan I Epstein, David James Harrison, Alan W Partin and Wim Van Criekinge (UGent)

(2016) In JOURNAL OF CLINICAL ONCOLOGY 34(2, suppl.).
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- Journal Article
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Detection of high-grade prostate cancer using a urinary molecular biomarker-based risk score

Leander Van Neste, Rianne J Hendriks, Siebren Dijkstra, Geert Trooskens (UGent) , Erik B Cornel, Sander A Jannink, Hans de Jong, Daphne Hessels, Frank P Smit, Willem JG Melchers, et al.

(2016) EUROPEAN UROLOGY. 70(5). p.740-748
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- Journal Article
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We are all individuals...: bioinformatics in the personalized medicine era

Leander Van Neste and Wim Van Criekinge (UGent)

(2015) CELLULAR ONCOLOGY. 38(1). p.29-37
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- Conference Paper
- C3
Risk stratification of aggressive prostate cancer based on combined epigenetic and clinical data of men with initial cancer-negative biopsies

Alan W Partin, Leander Van Neste, Grant D Stewart, Joseph Bigley, David J Harrison, Wim Van Criekinge (UGent) and Jonathan I Epstein

(2015) JOURNAL OF UROLOGY. 193(4, suppl.). p.E959-E960
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- Conference Paper
- C3
Epigenetic assay stratifies prostate cancer patients' risk for aggressiveness

Leander Van Neste, Wim Van Criekinge (UGent) , Joseph Bigley, William E Grizzle, George W Adams, Gary P Kearney and Sandra M Gaston

(2015) JOURNAL OF UROLOGY. 193(4, suppl.). p.E58-E59
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- Journal Article
- A1
Spectrin Repeat Containing Nuclear Envelope 1 and Forkhead Box Protein E1 are promising markers for the detection of colorectal cancer in blood

Veerle Melotte, Joo Mi Yi, Marjolein HFM Lentjes, Kim M Smits, Leander Van Neste, Hanneke EC Niessen, Kim AD Wouters, Joost Louwagie, Kornel E Schuebel, James G Herman, et al.

(2015) CANCER PREVENTION RESEARCH. 8(2). p.157-164
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- Conference Paper
- C3
Epigenetic profiling of prostate cancer tissue to identify men with high-risk disease

Leander Van Neste, Jeffrey Falk, Ming-Chou Lee, Joseph Bigley, Wim Van Criekinge (UGent) and E David Crawford

(2014) JOURNAL OF CLINICAL ONCOLOGY. 32(4, suppl.).
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- Conference Paper
- C3
Evaluation of different methods to assess homologous recombination status and sensitivity to PARP inhibitors in ovarian cancer

A Mukhopadhyay, M Dixon, E Mulligan, H Schuhwerk, J Murray, J Quinn, Leander Van Neste (UGent) , Wim Van Criekinge (UGent) , N Curtin and R Edmondson

(2014) INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER. 24(9, suppl. 4). p.353-354
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- Journal Article
- A1
Clinical validation of an epigenetic assay to predict negative histopathological results in repeat prostate biopsies

Alan W Partin, Leander Van Neste, Eric A Klein, Leonard S Marks, Jason R Gee, Dean A Troyer, Kimberly Rieger-Christ, J Stephen Jones, Cristina Magi-Galluzzi, Leslie A Mangold, et al.

(2014) JOURNAL OF UROLOGY. 192(4). p.1081-1087
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- Journal Article
- A1
Genome-wide methylation profiling reveals Zinc finger protein 516 (ZNF516) and FK-506binding protein 6 (FKBP6) promoters frequently methylated in cervical neoplasia, associated with HPV status and ethnicity in a Chilean population

Priscilla Brebi, Leonel Maldonado, Maartje G Noordhuis, Carmen Ili, Pamela Leal, Patricia Garcia, Mariana Brait, Judit Ribas, Christina Michailidi, Jimena Perez, et al.

(2014) EPIGENETICS. 9(2). p.308-317
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- Conference Paper
- C3
Prediction of risk for prostate cancer in histopathologically negative biopsies by multigene epigenetic assay

Leander Van Neste, Wim Van Criekinge (UGent) , Olivier Thas (UGent) , Joseph Bigley, Grant Duncan Stewart and David James Harrison

(2013) JOURNAL OF CLINICAL ONCOLOGY. 31(6, suppl.).
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- Journal Article
- A1
Clinical utility of an epigenetic assay to detect occult prostate cancer in histopathologically negative biopsies: results of the MATLOC study

Grant D Stewart, Leander Van Neste (UGent) , Philippe Delvenne, Paul Delrée, Agnès Delga, S Alan McNeill, Marie O'Donnell, James Clark, Wim Van Criekinge (UGent) , Joseph Bigley, et al.

(2013) JOURNAL OF UROLOGY. 189(3). p.1110-1116
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- Journal Article
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An exploration of pathways involved in lung carcinoid progression using gene expression profiling

Dorian RA Swarts, Leander Van Neste, Mieke ER Henfling, Ivo Eijkenboom, Paul P Eijk, Marie-Louise van Velthuysen, Aryan Vink, Marco Volante, Bauke Ylstra, Wim Van Criekinge (UGent) , et al.

(2013) CARCINOGENESIS. 34(12). p.2726-2737
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CD44 and OTP are strong prognostic markers for pulmonary carcinoids

Dorian RA Swarts, Mieke ER Henfling, Leander Van Neste (UGent) , Robert Jan van Suylen, Anne-Marie C Dingemans, Winand NM Dinjens, Annick Haesevoets, Martina Rudelius, Erik Thunnissen, Marco Volante, et al.

(2013) CLINICAL CANCER RESEARCH. 19(8). p.2197-2207
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- Journal Article
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The epigenetic promise for prostate cancer diagnosis.

Leander Van Neste (UGent) , James G Herman, Gaëtan Otto, Joseph W Bigley, Jonathan I Epstein and Wim Van Criekinge (UGent)

(2012) PROSTATE. 72(11). p.1248-1261
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A tissue biopsy-based epigenetic multiplex PCR assay for prostate cancer detection

Leander Van Neste (UGent) , Joseph Bigley, Adam Toll, Gaëtan Otto, James Clark, Paul Delrée, Wim Van Criekinge (UGent) and Jonathan I Epstein

(2012) BMC UROLOGY. 12.
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- Conference Paper
- C3
Genome‐wide RNA‐ and MBD‐sequencing in HCT116 and DKO cells as a global re‐expression model

Joachim De Schrijver (UGent) , Geert Trooskens (UGent) , Linda JW Bosch, Pierre Dehan, Beatriz Carvalho, Leander Van Neste (UGent) , Gerrit Meijer, Steve Baylin and Wim Van Criekinge (UGent)

(2012) Intelligent Systems for Molecular Biology, 20th Annual international conference, Abstracts.
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Biomarkers for detection and prognosis of breast cancer identified by a functional hypermethylome screen

Jana Jeschke, Leander Van Neste (UGent) , Sabine C Glöckner, Mashaal Dhir, Marilia Freitas Calmon, Valerie Deregowski, Wim Van Criekinge (UGent) , Ilse Vlassenbroeck, Alexander Koch (UGent) , Timothy A Chan, et al.

(2012) EPIGENETICS. 7(7). p.701-709
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- Journal Article
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High content image cytometry in the context of subnuclear organization

Winnok De Vos (UGent) , Leander Van Neste (UGent) , Birger Dieriks (UGent) , GH Joss and Patric Van Oostveldt (UGent)

(2010) CYTOMETRY PART A. 77A(1). p.64-75
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- Journal Article
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Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells

Joyce E Ohm, Prashant Mali, Leander Van Neste (UGent) , David M Berman, Liang Liang, Kurinji Pandiyan, Kimberley J Briggs, Wei Zhang, Pedram Argani, Brian Simons, et al.

(2010) CANCER RESEARCH. 70(19). p.7662-7673
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- PhD Thesis
Exploring the cancer Epigenome.

Leander Van Neste (UGent)

(2009)
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- Conference Paper
- C3
Prognostic significance of Gremlin1 (GREM1) promoter CPG island hypermethylation in clear cell renal cell carcinoma

Iris JH van Vlodrop, Marcella Baldewijns, Kim Smits, Leo Schouten, Leander Van Neste (UGent) , Wim Van Criekinge (UGent) , Hein van Poppel, Evelyne Lerut, Nita Ahuja, James Herman, et al.

(2009) CELLULAR ONCOLOGY. 31(2). p.119-119
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- Conference Paper
- C1
Pubmeth: reviewed methylation database in cancer based on text-mining

Maté Ongenaert (UGent) , Leander Van Neste (UGent) , Tim De Meyer (UGent) , Gerben Menschaert (UGent) , Sofie Bekaert (UGent) and Wim Van Criekinge (UGent)

(2008) ISMB 2008 Conference Proceedings.
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PubMeth: a cancer methylation database combining text-mining and expert annotation

Maté Ongenaert (UGent) , Leander Van Neste (UGent) , Tim De Meyer (UGent) , Gerben Menschaert (UGent) , Sofie Bekaert (UGent) and Wim Van Criekinge (UGent)

(2008) NUCLEIC ACIDS RESEARCH. 36.
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Defining a chromatin pattern that characterizes DNA-hypermethylated genes in colon cancer cells

KM MCGARVEY, Leander Van Neste (UGent) , L COPE, JE OHM, JG HERMANN, Wim Van Criekinge (UGent) , KE SCHUEBEL and SB BAYLIN

(2008) CANCER RESEARCH. 68(14). p.5753-5759
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Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3K4/K27 trimethylation

SD FOUSE, Y SHEN, M PELLEGRINI, S COLE, A MEISSNER, Leander Van Neste (UGent) , R JAENISCH and GP FAN

(2008) CELL STEM CELL. 2(2). p.160-169
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- Conference Paper
- C3
Methylation-induced silencing of TFPI-2 is an early-stage event in colorectal cancer

N AHUJA, S GLOCKNER, K SCHUEBEL, Leander Van Neste (UGent) , M VAN ENGELAND, M DHIR, K MCGARVEY and S BAYLIN

(2008) ANNALS OF SURGICAL ONCOLOGY. 15. p.90-90
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In vitro validation of gamma-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of T-cell acute lymphoblastic leukemia

K DE KEERSMAECKER, I LAHORTIGA, N MENTENS, C FOLENS, Leander Van Neste (UGent) , Sofie Bekaert (UGent) , P VANDENBERGHE, MD ODERO, P MARYNEN and J COOLS

(2008) HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. 93(4). p.533-542
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- Journal Article
- A1
Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis

TA CHAN, S GLOCKNER, JM YI, W CHEN, Leander Van Neste (UGent) , L COPE, JG HERMAN, V VELCULESCU, KE SCHUEBEL, N AHUJA, et al.

(2008) PLOS MEDICINE. 5(5). p.823-838
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Promoter methylation of genes in and around the candidate lung cancer susceptibility locus 6q23-25

M TESSEMA, R WILLINK, K DO, YY YU, W YU, EO MACHIDA, M BROCK, Leander Van Neste (UGent) , CA STIDLEY, SB BAYLIN, et al.

(2008) CANCER RESEARCH. 68(6). p.1707-1714
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Epigenetic inactivation of the canonical Wnt antagonist SRY-Box containing gene 17 in colorectal cancer

W ZHANG, SC GLOCKNER, MZ GUO, EO MACHIDA, DH WANG, H EASWARAN, Leander Van Neste (UGent) , JG HERMAN, KE SCHUEBEL, DN WATKINS, et al.

(2008) CANCER RESEARCH. 68(8). p.2764-2772
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Comprehensive genomic characterization defines human glioblastoma genes and core pathways

L Chin, M Meyerson, K Aldape, D Bigner, T Mikkelsen, S VandenBerg, A Kahn, R Penny, ML Ferguson, DS Gerhard, et al.

(2008) NATURE. 455(7216). p.1061-1068
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- open access
Relation between telomerase activity, hTERT and telomere length for intracranial tumours

Lode Maes (UGent) , Leander Van Neste (UGent) , K Van Damme, Jean-Pierre Kalala Okito (UGent) , Leo De Ridder, Sofie Bekaert (UGent) and Maria Cornelissen (UGent)

(2007) ONCOLOGY REPORTS. 18(6). p.1571-1576
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Comparing the DNA hypermethylome with gene mutations in human colorectal cancer

KE SCHUEBEL, W CHEN, L COPE, SC GLOCKNER, H SUZUKI, JM YI, TA CHAN, Leander Van Neste (UGent) , Wim Van Criekinge (UGent) , S VAN DEN BOSCH, et al.

(2007) PLOS GENETICS. 3(9). p.1709-1723

Evaluation of an epigenetic assay for predicting repeat prostate biopsy outcome in African American men

Analysis of DNA methylation in cancer : location revisited

Cost-effectiveness of a new urinary biomarker-based risk score compared to standard of care in prostate cancer diagnostics : a decision analytical model

Epigenetic risk score improves prostate cancer risk assessment

Clinical performance of an epigenetic assay to identify occult high-grade prostate cancer in African American men

A four-gene promoter methylation marker panel consisting of GREM1, NEURL, LAD1, and NEFH predicts survival of clear cell renal cell cancer patients

Evaluation of an epigenetic profile for the detection of bladder cancer in patients with hematuria

Identification of high-grade prostate cancer using urine-based molecular biomarkers combined with clinical risk factors

Risk score predicts high-grade prostate cancer in DNA-methylation positive, histopathologically negative biopsies

Clinical utility of an epigenetic assay to reduce unnecessary repeat prostate biopsies

Ability of an epigenetic assay to identify anterior prostate tumors based on a negative 12-core biopsy

Combined DNA-methylation intensity and clinical risk score to stratify patients for high-grade disease

Detection of high-grade prostate cancer using a urinary molecular biomarker-based risk score

We are all individuals...: bioinformatics in the personalized medicine era

Risk stratification of aggressive prostate cancer based on combined epigenetic and clinical data of men with initial cancer-negative biopsies

Epigenetic assay stratifies prostate cancer patients' risk for aggressiveness

Spectrin Repeat Containing Nuclear Envelope 1 and Forkhead Box Protein E1 are promising markers for the detection of colorectal cancer in blood

Epigenetic profiling of prostate cancer tissue to identify men with high-risk disease

Evaluation of different methods to assess homologous recombination status and sensitivity to PARP inhibitors in ovarian cancer

Clinical validation of an epigenetic assay to predict negative histopathological results in repeat prostate biopsies

Genome-wide methylation profiling reveals Zinc finger protein 516 (ZNF516) and FK-506binding protein 6 (FKBP6) promoters frequently methylated in cervical neoplasia, associated with HPV status and ethnicity in a Chilean population

Prediction of risk for prostate cancer in histopathologically negative biopsies by multigene epigenetic assay

Clinical utility of an epigenetic assay to detect occult prostate cancer in histopathologically negative biopsies: results of the MATLOC study

An exploration of pathways involved in lung carcinoid progression using gene expression profiling

CD44 and OTP are strong prognostic markers for pulmonary carcinoids

The epigenetic promise for prostate cancer diagnosis.

A tissue biopsy-based epigenetic multiplex PCR assay for prostate cancer detection

Genome‐wide RNA‐ and MBD‐sequencing in HCT116 and DKO cells as a global re‐expression model

Biomarkers for detection and prognosis of breast cancer identified by a functional hypermethylome screen

High content image cytometry in the context of subnuclear organization

Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells

Exploring the cancer Epigenome.

Prognostic significance of Gremlin1 (GREM1) promoter CPG island hypermethylation in clear cell renal cell carcinoma

Pubmeth: reviewed methylation database in cancer based on text-mining

PubMeth: a cancer methylation database combining text-mining and expert annotation

Defining a chromatin pattern that characterizes DNA-hypermethylated genes in colon cancer cells

Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3K4/K27 trimethylation

Methylation-induced silencing of TFPI-2 is an early-stage event in colorectal cancer

In vitro validation of gamma-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of T-cell acute lymphoblastic leukemia

Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis

Promoter methylation of genes in and around the candidate lung cancer susceptibility locus 6q23-25

Epigenetic inactivation of the canonical Wnt antagonist SRY-Box containing gene 17 in colorectal cancer

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Relation between telomerase activity, hTERT and telomere length for intracranial tumours

Comparing the DNA hypermethylome with gene mutations in human colorectal cancer