Ghent University Academic Bibliography

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CAR-T in the treatment of acute myeloid leukemia : barriers and how to overcome them

Jolien Vanhooren (UGent) , Rani Dobbelaere, Charlotte Derpoorter (UGent) , Larissa Deneweth (UGent) , Laurens Van Camp (UGent) , Anne Uyttebroeck, Barbara De Moerloose (UGent) and Tim Lammens

(2023) HEMASPHERE. 7(9).
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The prognostic value of IKZF1(plus) in B‐cell progenitor acute lymphoblastic leukemia : results from the EORTC 58951 trial

Michal Kicinski, Chloé Arfeuille, Nathalie Grardel, Marleen Bakkus, Aurélie Caye‐Eude, Geneviève Plat, Alina Ferster, Anne Uyttebroeck, Barbara De Moerloose (UGent) , Pierre Rohrlich, et al.

(2023) PEDIATRIC BLOOD & CANCER. 70(6).
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Immunoglobulin heavy chain high-throughput sequencing in pediatric B-precursor acute lymphoblastic leukemia : is the clonality of the disease at diagnosis related to its prognosis?

Gabriel Levy, Michal Kicinski, Jona Van der Straeten, Anne Uyttebroeck, Alina Ferster, Barbara De Moerloose (UGent) , Marie-Francoise Dresse, Christophe Chantrain, Bénédicte Brichard and Marleen Bakkus

(2022) FRONTIERS IN PEDIATRICS. 10.
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Deciphering the non-coding RNA landscape of pediatric acute myeloid leukemia

Jolien Vanhooren (UGent) , Laurens Van Camp (UGent) , Barbara Depreter, Martijn de Jong (UGent) , Anne Uyttebroeck, An Van Van Damme, Laurence Dedeken, Marie-Françoise Dresse, Jutte van der Werff ten Bosch, Mattias Hofmans (UGent) , et al.

(2022) CANCERS. 14(9).
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Deciphering the non-coding landscape of pediatric acute myeloid leukemia

Jolien Vanhooren (UGent) , Laurens Van Camp (UGent) , Barbara Depreter, Martijn de Jong (UGent) , Anne Uyttebroeck, An Van Damme, Laurence Dedeken, Marie-Françoise Dresse, Jutte van der Werff ten Bosch, Mattias Hofmans (UGent) , et al.

(2022) BVK (Belgische Vereniging voor Kindergeneeskunde) Congress 2022, Abstracts.
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Deciphering the non-coding landscape of pediatric acute myeloid leukemia

Laurens Van Camp (UGent) , Jolien Vanhooren (UGent) , Barbara Depreter, Martijn de Jong (UGent) , Anne Uyttebroeck, An Van Damme, Laurence Dedeken, Marie-Françoise Dresse, Jutte van der Werff ten Bosch, Mattias Hofmans (UGent) , et al.

(2022) 54th annual SIOP Congress 2022, Abstracts.
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Current developments and hurdles in CAR-T cell therapy for acute myeloid leukaemia

Laurens Van Camp (UGent) , Tim Lammens (UGent) , Anne Uyttebroeck and Barbara De Moerloose (UGent)

(2021) BELGIAN JOURNAL OF HEMATOLOGY. 12(6). p.244-250
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Deciphering molecular heterogeneity in pediatric AML using a cancer vs. normal transcriptomic approach

Barbara Depreter, Barbara De Moerloose (UGent) , Karl Vandepoele (UGent) , Anne Uyttebroeck, An Van Damme, Eva Terras (UGent) , Barbara Denys (UGent) , Laurence Dedeken, Marie-Francoise Dresse, Jutte Van der Werff Ten Bosch, et al.

(2021) PEDIATRIC RESEARCH. 89(7). p.1695-1705
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Pediatric randomized trial EORTC CLG 58951 : outcome for adolescent population with acute lymphoblastic leukemia

Laura Olivier-Gougenheim, Chloe Arfeuille, Stefan Suciu, Nicolas Sirvent, Genevieve Plat, Alina Ferster, Barbara De Moerloose (UGent) , Carine Domenech, Anne Uyttebroeck, Pierre-Simon Rohrlich, et al.

(2020) HEMATOLOGICAL ONCOLOGY. 38(5). p.763-772
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Clinical significance of TARP expression in pediatric acute myeloid leukemia

Barbara Depreter, Barbara De Moerloose (UGent) , Karl Vandepoele (UGent) , Anne Uyttebroeck, An Van Damme, Barbara Denys, Laurence Dedeken, Marie-Françoise Dresse, Jutte Van Der Werff Ten Bosch, Mattias Hofmans (UGent) , et al.

(2020) HEMASPHERE. 4(2).
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Prospective, real-time monitoring of pegylated Escherichia coli and Erwinia asparaginase therapy in childhood acute lymphoblastic leukaemia and non-Hodgkin lymphoma in Belgium

Veerle Mondelaers (UGent) , Alina Ferster, Anne Uyttebroeck, Benedicte Brichard, Juttevan der Werff ten Bosch, Koenraad Norga, Nadine Francotte, Caroline Piette, Katrien Vandemeulebroecke (UGent) , Charlotte Verbeke, et al.

(2020) BRITISH JOURNAL OF HAEMATOLOGY. 190(1). p.105-114
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TARP is an immunotherapeutic target in acute myeloid leukemia expressed in the leukemic stem cell compartment

Barbara Depreter, Karin Weening (UGent) , Karl Vandepoele (UGent) , Magnus Essand, Barbara De Moerloose (UGent) , Maria Themeli, Jacqueline Cloos, Diana Hanekamp, Ine Moors (UGent) , Inge D'hont (UGent) , et al.

(2020) HAEMATOLOGICA. 105(5). p.1306-1316
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Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

Renate De Smedt (UGent) , Julie Morscio (UGent) , Lindy Reunes (UGent) , Juliette Roels (UGent) , Valentina Bardelli, Béatrice Lintermans (UGent) , Wouter Van Loocke (UGent) , Afonso Almeida, Laurence C. Cheung, Rishi S. Kotecha, et al.

(2020) BLOOD. 135(19). p.1685-1695
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The strategic plan for paediatric cancer treatment in Belgium

A Van Damme, Barbara De Moerloose (UGent) , B Brichard, A Ferster, B Heenen, Genevieve Laureys (UGent) , Koen Norga, C Piette, Jutte Van Der Werff Ten Bosch and Anne Uyttebroeck

(2019) BELGIAN JOURNAL OF MEDICAL ONCOLOGY. 13(1). p.21-26
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Deciphering molecular heterogeneity in pediatric AML using a cancer vs normal transcriptomic approach

Barbara Depreter, Mattias Hofmans (UGent) , Eva Terras (UGent) , Anne Uyttebroeck, An Van Damme, Alina Ferster, Jutte Van der Werff Ten Bosch, Marie-Françoise Dresse, Karl Vandepoele (UGent) , Barbara De Moerloose (UGent) , et al.

(2019) BLOOD. 134(S1). p.1457-1457
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Deciphering molecular heterogeneity in pediatric AML using a cancer vs normal transcriptomic approach

Barbara Depreter, Mattias Hofmans (UGent) , Eva Terras (UGent) , Anne Uyttebroeck, An Van Damme, Alina Ferster, Jutte van der Werff ten Bosch, Marie-Françoise Dresse, Karl Vandepoele (UGent) , Barbara De Moerloose (UGent) , et al.

(2019) American Society of Hematology, 61st Annual meeting, Abstracts.
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Response-guided chemotherapy for pediatric acute myeloid leukemia without hematopoietic stem cell transplantation in first complete remission: Results from protocol DB AML-01

Barbara De Moerloose (UGent) , Ardine Reedijk, Geertruida H. de Bock, Tim Lammens (UGent) , Valerie de Haas, Barbara Denys (UGent) , Laurence Dedeken, Marry M. van den Heuvel-Eibrink, Maroeska te Loo, Anne Uyttebroeck, et al.

(2019) PEDIATRIC BLOOD & CANCER. 66(5).
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Results of successive EORTC-CLG 58 881 and 58 951 trials in paediatric T-cell acute lymphoblastic leukaemia (ALL)

Mattias Hofmans (UGent) , Stefan Suciu, Alina Ferster, Pieter Van Vlierberghe (UGent) , Françoise Mazingue, Nicolas Sirvent, Vitor Costa, Karima Yakouben, Catherine Paillard, Anne Uyttebroeck, et al.

(2019) BRITISH JOURNAL OF HAEMATOLOGY. 186(5). p.741-753
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Pre-clinical evaluation of second generation PIM inhibitors for the treatment of T-cell acute lymphoblastic leukemia and lymphoma

Renate De Smedt (UGent) , Sofie Peirs (UGent) , Julie Morscio (UGent) , Filip Matthijssens (UGent) , Juliette Roels (UGent) , Lindy Reunes (UGent) , Béatrice Lintermans (UGent) , Steven Goossens (UGent) , Tim Lammens (UGent) , Nadine Van Roy (UGent) , et al.

(2018) HAEMATOLOGICA. 104(1). p.e17-e20
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The role of the MTHFR C677T polymorphism in methotrexate-induced toxicity in pediatric osteosarcoma patients

Loes Lambrecht, Charlotte Sleurs, Veerle Labarque, Catharina Dhooge (UGent) , Annouschka Laenen, Friedl Sinnaeve, Marleen Renard and Anne Uyttebroeck

(2017) PHARMACOGENOMICS. 18(8). p.787-795
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Intellectual development of childhood ALL patients : a multicenter longitudinal study

Charlotte Sleurs, Jurgen Lemiere, Trui Vercruysse, Nathalie Nolf (UGent) , Ben Van Calster, Sabine Deprez, Marleen Renard, Els Vandecruys (UGent) , Yves Benoit and Anne Uyttebroeck

(2017) PSYCHO-ONCOLOGY. 26(4). p.508-514
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Prolonged versus standard native E-coli asparaginase therapy in childhood acute lymphoblastic leukemia and non-Hodgkin lymphoma : final results of the EORTC-CLG randomized phase III trial 58951

Veerle Mondelaers (UGent) , Stefan Suciu, Barbara De Moerloose (UGent) , Alina Ferster, Francoise Mazingue, Geneviève Plat, Karima Yakouben, Anne Uyttebroeck, Patrick Lutz, Vitor Costa, et al.

(2017) HAEMATOLOGICA. 102(10). p.1727-1738
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Unique long non-coding RNA expression signature in ETV6/RUNX1-Driven B-cell precursor acute lymphoblastic leukemia

Farzaneh Ghazavi (UGent) , Barbara De Moerloose (UGent) , Wouter Van Loocke (UGent) , Annelynn Wallaert (UGent) , Alina Ferster, Marleen Bakkus, Geneviève Plat, Eric Delabesse, Anne Uyttebroeck, Filip Van Nieuwerburgh (UGent) , et al.

(2016) BLOOD. 128(22).
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Unique long non-coding RNA expression signature in ETV6/RUNX1-driven B-cell precursor acute lymphoblastic leukemia

Farzaneh Ghazavi (UGent) , Barbara De Moerloose (UGent) , Wouter Van Loocke (UGent) , Annelynn Wallaert (UGent) , Hetty Helsmoortel (UGent) , Alina Ferster, Marleen Bakkus, Geneviève Plat, Eric Delabesse, Anne Uyttebroeck, et al.

(2016) ONCOTARGET. 7(45). p.73769-73780
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Excellent outcome in pediatric AML with response guided chemotherapy without allogeneic HSCT in first complete remission results from prococol DB-AML01

Eveline de Bont, Ardine Reedijk, Tim Lammens (UGent) , Valerie de Haas, Barbara Denys, Laurence Dedeken, Marry van den Heuvel, Maroeska te Loo, Anne Uyttebroeck, An Vandamme, et al.

(2015) BLOOD. 126(23).
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CD200/BTLA deletions in pediatric precursor B-cell acute lymphoblastic leukemia treated according to the EORTC-CLG 58951 protocol

Farzaneh Ghazavi (UGent) , Emmanuelle Clappier, Tim Lammens (UGent) , Stefan Suciu, Aurélie Caye, Samira Zegrari, Marleen Bakkus, Nathalie Grardel, Yves Benoit, Odile Minckes, et al.

(2015) HAEMATOLOGICA. 100(10). p.1311-1319
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Integrative genomic and transcriptomic analysis identified candidate genes implicated in the pathogenesis of hepatosplenic T-cell lymphoma

Julio Finalet Ferreiro, Leila Rouhigharabaei, Helena Urbankova, Jo-Anne van der Krogt, Lucienne Michaux, Shashirekha Shetty, Laszlo Krenacs, Thomas Tousseyn, Pascale De Paepe, Anne Uyttebroeck, et al.

(2014) PLOS ONE. 9(7).
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LIN28B defines an aggressive subtype of juvenile myelomonocytic leukemia

Hetty Helsmoortel (UGent) , Tim Lammens (UGent) , Farzaneh Ghazavi (UGent) , Aurelie Caye, Hélène Cavé, Christian Flotho, Charlotte Niemeyer, Jan Stary, Silvia Bresolin, Riccardo Masetti, et al.

(2014) HAEMATOLOGICA. 99(suppl. 1). p.235-236
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Dexamethasone (6 mg/m²/day) and prednisolone (60 mg/m²/day) were equally effective as induction therapy for childhood acute lymphoblastic leukemia in the EORTC CLG 58951 randomized trial

Carine Domenech, Stefan Suciu, Barbara De Moerloose (UGent) , Françoise Mazingue, Geneviève Plat, Alina Ferster, Anne Uyttebroeck, Nicolas Sirvent, Patrick Lutz, Karima Yakouben, et al.

(2014) HAEMATOLOGICA. 99(7). p.1220-1227
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Prognostic relevance of CD200/BTLA deletions in pediatric precursor-B cell acute lymphoblastic leukemia treated according to the EORTD-CLG 58951 protocol

Farzaneh Ghazavi (UGent) , Tim Lammens (UGent) , Emmanuelle Clappier, Stefan Suciu, Aurélie Caye, Samira Zegrari, Marleen Bakkus, Nathalie Grardel, Yves Benoit, Yves Bertrand, et al.

(2014) BLOOD. 124(21).
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miRNAs distinguish children with myelodysplastic syndrome from healthy donors

Hetty Helsmoortel (UGent) , Tim Lammens (UGent) , Pieter Mestdagh (UGent) , Nadine Van Roy (UGent) , Anne Uyttebroeck, Alina Ferster, Yves Benoit, Jo Vandesompele (UGent) , Franki Speleman (UGent) , Pieter Van Vlierberghe (UGent) , et al.

(2013) Belgian Society of Human Genetics, 13th Annual meeting, Abstracts. p.163-163
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miRNAs distinguish children with myelodysplastic syndrome from healthy donors

Hetty Helsmoortel (UGent) , Tim Lammens (UGent) , Pieter Mestdagh (UGent) , Nadine Van Roy (UGent) , Anne Uyttebroeck, Alina Ferster, Yves Benoit, Jo Vandesompele (UGent) , Franki Speleman (UGent) , Pieter Van Vlierberghe (UGent) , et al.

(2013) Belgian Hematological Society, 28th General annual meeting, Abstracts. p.27-27
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Comprehensive analysis of transcriptome variation uncovers known and novel driver events in T-cell acute lymphoblastic leukemia

Zeynep Kalender Atak, Valentina Gianfelici, Gert Hulselmans, Kim De Keersmaecker, Arun George Devasia, Ellen Geerdens, Nicole Mentens, Sabina Chiaretti, Kaat Durinck (UGent) , Anne Uyttebroeck, et al.

(2013) PLOS GENETICS. 9(12).
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Hyperdiploidy with 58-66 chromosomes in childhood B-acute lymphoblastic leukemia is highly curable: 58951 CLG-EORTC results

Nicole Dastugue, Stefan Suciu, Geneviève Plat, Franki Speleman (UGent) , Hélène Cavé, Sandrine Girard, Marleen Bakkus, Marie Pierre Pagès, Karima Yakouben, Brigitte Nelken, et al.

(2013) BLOOD. 121(13). p.2415-2423
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Study of the miRNome of childhood myelodysplastic syndrome

Hetty Helsmoortel (UGent) , Tim Lammens (UGent) , Nadine Van Roy (UGent) , Anne Uyttebroeck, Alina Ferster, Yves Benoit, Franki Speleman (UGent) and Barbara De Moerloose (UGent)

(2012) HAEMATOLOGICA. 97(suppl. 3). p.S1-S1
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Improved risk stratification and outcome prediction in children with average risk 1 precursor-B acute lymphoblastic leukemia using a 19-microRNA signature

Farzaneh Ghazavi (UGent) , Tim Lammens (UGent) , Stefan Suciu, Genevieve Laureys (UGent) , Marleen Bakkus, Alina Ferster, Anne Uyttebroeck, Patrick Lutz, Hélène Cavé, Geneviève Plat, et al.

(2012) European Hematology Association, 17th Congress, Abstracts.
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Improved risk-stratification and outcome prediction in children with average risk precursor-B acute lymphoblastic leukemia using a 19-microRNA signature

Farzaneh Ghazavi (UGent) , Tim Lammens (UGent) , Stefan Suciu, Genevieve Laureys (UGent) , Marleen Bakkus, Alina Ferster, Anne Uyttebroeck, Patrick Lutz, Hélène Cavé, Geneviève Plat, et al.

(2012) Belgian Hematological Society, 27th General annual meeting, Abstracts.
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Similar efficacy and toxicity profile for Idarubicine and Mitoxantrone in induction and intensification treatment of children with acute myeloid leukemia (AML) or myelodysplasia (MDS): long-term results of the EORTC-CLG randomized phase III trial 58921

Barbara De Moerloose (UGent) , Stefan Suciu, Martine Munzer, Caroline Piette, Karima Yakouben, Genevieve Margueritte, Patrick Lutz, Anne Uyttebroeck, Pierre Rohrlich, Alina Ferster, et al.

(2011) 53rd ASH annual meeting and exposition : abstracts, program and personal scheduler.
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Improved outcome with pulses of vincristine and corticosteroids in continuation therapy of children with average risk acute lymphoblastic leukemia (ALL) and lymphoblastic non-Hodgkin lymphoma (NHL): report of the EORTC randomized phase 3 trial 58951

Barbara De Moerloose (UGent) , Stefan Suciu, Yves Bertrand, Françoise Mazingue, Alain Robert, Anne Uyttebroeck, Karima Yakouben, Alice Ferster, Geneviève Margueritte, Patrick Lutz, et al.

(2010) BLOOD. 116(1). p.36-44
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Treatment of childhood T-cell lymphoblastic lymphoma according to the strategy for acute lymphoblastic leukaemia, without radiotherapy: Long term results of the EORTC CLG 58881 trial

Anne Uyttebroeck, Stefan Suciu, Genevieve Laureys (UGent) , Alain Robert, Helene Pacquement, Alina Ferster, Genevieve Marguerite, Francoise Mazingue, Marleen Renard, Patrick Lutz, et al.

(2008) EUROPEAN JOURNAL OF CANCER. 44(6). p.840-846

CAR-T in the treatment of acute myeloid leukemia : barriers and how to overcome them

The prognostic value of IKZF1(plus) in B‐cell progenitor acute lymphoblastic leukemia : results from the EORTC 58951 trial

Immunoglobulin heavy chain high-throughput sequencing in pediatric B-precursor acute lymphoblastic leukemia : is the clonality of the disease at diagnosis related to its prognosis?

Deciphering the non-coding RNA landscape of pediatric acute myeloid leukemia

Deciphering the non-coding landscape of pediatric acute myeloid leukemia

Deciphering the non-coding landscape of pediatric acute myeloid leukemia

Current developments and hurdles in CAR-T cell therapy for acute myeloid leukaemia

Deciphering molecular heterogeneity in pediatric AML using a cancer vs. normal transcriptomic approach

Pediatric randomized trial EORTC CLG 58951 : outcome for adolescent population with acute lymphoblastic leukemia

Clinical significance of TARP expression in pediatric acute myeloid leukemia

Prospective, real-time monitoring of pegylated Escherichia coli and Erwinia asparaginase therapy in childhood acute lymphoblastic leukaemia and non-Hodgkin lymphoma in Belgium

TARP is an immunotherapeutic target in acute myeloid leukemia expressed in the leukemic stem cell compartment

Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

The strategic plan for paediatric cancer treatment in Belgium

Deciphering molecular heterogeneity in pediatric AML using a cancer vs normal transcriptomic approach

Deciphering molecular heterogeneity in pediatric AML using a cancer vs normal transcriptomic approach

Response-guided chemotherapy for pediatric acute myeloid leukemia without hematopoietic stem cell transplantation in first complete remission: Results from protocol DB AML-01

Results of successive EORTC-CLG 58 881 and 58 951 trials in paediatric T-cell acute lymphoblastic leukaemia (ALL)

Pre-clinical evaluation of second generation PIM inhibitors for the treatment of T-cell acute lymphoblastic leukemia and lymphoma

The role of the MTHFR C677T polymorphism in methotrexate-induced toxicity in pediatric osteosarcoma patients

Intellectual development of childhood ALL patients : a multicenter longitudinal study

Prolonged versus standard native E-coli asparaginase therapy in childhood acute lymphoblastic leukemia and non-Hodgkin lymphoma : final results of the EORTC-CLG randomized phase III trial 58951

Unique long non-coding RNA expression signature in ETV6/RUNX1-Driven B-cell precursor acute lymphoblastic leukemia

Unique long non-coding RNA expression signature in ETV6/RUNX1-driven B-cell precursor acute lymphoblastic leukemia

Excellent outcome in pediatric AML with response guided chemotherapy without allogeneic HSCT in first complete remission results from prococol DB-AML01

CD200/BTLA deletions in pediatric precursor B-cell acute lymphoblastic leukemia treated according to the EORTC-CLG 58951 protocol

Integrative genomic and transcriptomic analysis identified candidate genes implicated in the pathogenesis of hepatosplenic T-cell lymphoma

LIN28B defines an aggressive subtype of juvenile myelomonocytic leukemia

Dexamethasone (6 mg/m²/day) and prednisolone (60 mg/m²/day) were equally effective as induction therapy for childhood acute lymphoblastic leukemia in the EORTC CLG 58951 randomized trial

Prognostic relevance of CD200/BTLA deletions in pediatric precursor-B cell acute lymphoblastic leukemia treated according to the EORTD-CLG 58951 protocol

miRNAs distinguish children with myelodysplastic syndrome from healthy donors

miRNAs distinguish children with myelodysplastic syndrome from healthy donors

Comprehensive analysis of transcriptome variation uncovers known and novel driver events in T-cell acute lymphoblastic leukemia

Hyperdiploidy with 58-66 chromosomes in childhood B-acute lymphoblastic leukemia is highly curable: 58951 CLG-EORTC results

Study of the miRNome of childhood myelodysplastic syndrome

Improved risk stratification and outcome prediction in children with average risk 1 precursor-B acute lymphoblastic leukemia using a 19-microRNA signature

Improved risk-stratification and outcome prediction in children with average risk precursor-B acute lymphoblastic leukemia using a 19-microRNA signature

Similar efficacy and toxicity profile for Idarubicine and Mitoxantrone in induction and intensification treatment of children with acute myeloid leukemia (AML) or myelodysplasia (MDS): long-term results of the EORTC-CLG randomized phase III trial 58921

Improved outcome with pulses of vincristine and corticosteroids in continuation therapy of children with average risk acute lymphoblastic leukemia (ALL) and lymphoblastic non-Hodgkin lymphoma (NHL): report of the EORTC randomized phase 3 trial 58951

Treatment of childhood T-cell lymphoblastic lymphoma according to the strategy for acute lymphoblastic leukaemia, without radiotherapy: Long term results of the EORTC CLG 58881 trial