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Airway epithelial cell necroptosis contributes to asthma exacerbation in a mouse model of house dust mite-induced allergic inflammation
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Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation
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- Journal Article
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OTULIN prevents liver inflammation and hepatocellular carcinoma by inhibiting FADD- and RIPK1 kinase-mediated hepatocyte apoptosis
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Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis
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A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms
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A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain
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- open access
Molecular mechanisms of cell death : recommendations of the Nomenclature Committee on Cell Death 2018
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TLR-independent anti-inflammatory function of intestinal epithelial TRAF6 signalling prevents DSS-induced colitis in mice
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NEMO prevents RIP kinase 1-mediated epithelial cell death and chronic intestinal inflammation by NF-κB-dependent and -independent functions
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Necroptosis and its role in inflammation
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Synchronized renal tubular cell death involves ferroptosis
(2014) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 111(47). p.16836-16841 -
- Journal Article
- A1
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Bacteria regulate intestinal epithelial cell differentiation factors both in vitro and in vivo
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- Journal Article
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A20 (Tnfaip3) deficiency in myeloid cells protects against influenza A virus infection
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Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway
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CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair
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Conditional targeting of tumor necrosis factor receptor-associated factor 6 reveals opposing functions of toll-like receptor signaling in endothelial and myeloid cells in a mouse model of atherosclerosis
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The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation
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FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation
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- Journal Article
- A1
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Constitutive IKK2 activation in intestinal epithelial cells induces intestinal tumors in mice
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NF-κB in the regulation of epithelial homeostasis and inflammation
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I kappa B kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-kappa B in the central nervous system
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A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis
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A20 (TNFAIP3) deficiency in myeloid cells triggers rheumatoid arthritis
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Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis
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Oligodendrocyte-specific FADD deletion protects mice from autoimmune-mediated demyelination
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- Journal Article
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Generalized immune activation as a direct result of activated CD4+ T cell killing
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Development of immunoglobulin lambda-chain-positive B cells, but not editing of immunoglobulin kappa-chain, depends on NF-kappa B signals
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Identification of oxidative stress and toll-like receptor 4 signaling as a key pathway of acute lung injury
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Epithelial NEMO links innate immunity to chronic intestinal inflammation
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Deletion of NEMO/IKKγ in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma
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Inhibition of transcription factor NF-κB in the central nervous system ameliorates autoimmune encephalomyelitis in mice