Ghent University Academic Bibliography

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Your filters: cql: author="Pasparakis, Manolis*" or (type exact bookEditor and editor="Pasparakis, Manolis*")

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Airway epithelial cell necroptosis contributes to asthma exacerbation in a mouse model of house dust mite-induced allergic inflammation

Nikos Oikonomou, Martijn Schuijs (UGent) , Antonis Chatzigiagkos, Ariadne Androulidaki, Vassilis Aidinis, Hamida Hammad (UGent) , Bart Lambrecht (UGent) and Manolis Pasparakis

(2021) MUCOSAL IMMUNOLOGY.
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Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation

Lucie Laurien, Masahiro Nagata, Hannah Schünke, Tom Delanghe (UGent) , Janica L. Wiederstein, Snehlata Kumari, Robin Schwarzer, Teresa Corona, Marcus Krüger, Mathieu Bertrand (UGent) , et al.

(2020) NATURE COMMUNICATIONS. 11(1).
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OTULIN prevents liver inflammation and hepatocellular carcinoma by inhibiting FADD- and RIPK1 kinase-mediated hepatocyte apoptosis

Lien Verboom (UGent) , Arne Martens (UGent) , Dario Priem (UGent) , Esther Hoste (UGent) , Mozes Sze (UGent) , Hanna-Kaisa Vikkula (UGent) , Lisette Van Hove (UGent) , Sofie Voet, Jana Roels (UGent) , Jonathan Maelfait (UGent) , et al.

(2020) CELL REPORTS. 30(7). p.2237-2247
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Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis

Melanie Fritsch, Saskia D Gunther, Robin Schwarzer, Marie-Christine Albert, Fabian Schorn, J Paul Werthenbach, Lars M Schiffmann, Neil Stair, Hannah Stocks, Jens M Seeger, et al.

(2019) NATURE. 575(7784). p.683-687
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A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms

Dario Priem (UGent) , Michael Devos, Sarah Druwé, Arne Martens (UGent) , Karolina Slowicka (UGent) , Adrian T Ting, Manolis Pasparakis, Wim Declercq (UGent) , Peter Vandenabeele (UGent) , Geert van Loo (UGent) , et al.

(2019) CELL DEATH & DISEASE. 10.
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A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain

Apostolos Polykratis, Arne Martens (UGent) , Remzi Onur Eren, Yoshitaka Shirasaki, Mai Yamagishi, Yoshifumi Yamaguchi, Sotaro Uemura, Masayuki Miura, Bernhard Holzmann, George Kollias, et al.

(2019) NATURE CELL BIOLOGY. 21(6). p.731-742
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Molecular mechanisms of cell death : recommendations of the Nomenclature Committee on Cell Death 2018

Lorenzo Galluzzi, Ilio Vitale, Stuart A Aaronson, John M Abrams, Dieter Adam, Patrizia Agostinis, Emad S Alnemri, Lucia Altucci, Ivano Amelio, David W. Andrews, et al.

(2018) CELL DEATH AND DIFFERENTIATION. 25(3). p.486-541
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TLR-independent anti-inflammatory function of intestinal epithelial TRAF6 signalling prevents DSS-induced colitis in mice

Katerina Vlantis, Apostolos Polykratis, Patrick-Simon Welz, Geert van Loo (UGent) , Manolis Pasparakis and Andy Wullaert (UGent)

(2016) GUT. 65(6). p.935-943
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NEMO prevents RIP kinase 1-mediated epithelial cell death and chronic intestinal inflammation by NF-κB-dependent and -independent functions

Katerina Vlantis, Andy Wullaert (UGent) , Apostolos Polykratis, Vangelis Kondylis, Marius Dannappel, Robin Schwarzer, Patrick Welz, Teresa Corona, Henning Walczak, Falk Weih, et al.

(2016) IMMUNITY. 44(3). p.553-567
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Necroptosis and its role in inflammation

Manolis Pasparakis and Peter Vandenabeele (UGent)

(2015) NATURE. 517(7534). p.311-320
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Synchronized renal tubular cell death involves ferroptosis

Andreas Linkermann, Rachid Skouta, Nina Himmerkus, Sshrikant R Mulay, Christin Dewitz, Federica De Zen, Agnes Prokai, Gabriele Zuchtriegel, Fritz Krombach, Patrick-Simon Welz, et al.

(2014) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 111(47). p.16836-16841
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Bacteria regulate intestinal epithelial cell differentiation factors both in vitro and in vivo

Svetlana Becker, Tobias A Oelschlaeger, Andy Wullaert (UGent) , Manolis Pasparakis, Jan Wehkamp, Eduard F Stange and Michael Gersemann

(2013) PLOS ONE. 8(2).
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A20 (Tnfaip3) deficiency in myeloid cells protects against influenza A virus infection

Jonathan Maelfait (UGent) , Kenny Roose (UGent) , Pieter Bogaert (UGent) , Mozes Sze (UGent) , Xavier Saelens (UGent) , Manolis Pasparakis, Isabelle Carpentier (UGent) , Geert van Loo (UGent) and Rudi Beyaert (UGent)

(2012) PLOS PATHOGENS. 8(3).
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Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway

Monika Julia Wolf, Alexandra Hoos, Judith Bauer, Steffen Boettcher, Markus Knust, Achim Weber, Nicole Simonavicius, Christoph Schneider, Matthias Lang, Michael Sturzl, et al.

(2012) CANCER CELL. 22(1). p.91-105
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CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair

Sebastian Willenborg, Tina Lucas, Geert van Loo (UGent) , Johanna A Knipper, Thomas Krieg, Ingo Haase, Bent Brachvogel, Matthias Hammerschmidt, Andras Nagy, Napoleone Ferrara, et al.

(2012) BLOOD. 120(3). p.613-625
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Conditional targeting of tumor necrosis factor receptor-associated factor 6 reveals opposing functions of toll-like receptor signaling in endothelial and myeloid cells in a mouse model of atherosclerosis

Apostolos Polykratis, Geert van Loo (UGent) , Sofia Xanthoulea, Martin Hellmich and Manolis Pasparakis

(2012) CIRCULATION. 126(14). p.1739-1751
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The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation

Marion C Bonnet, Daniela Preukschat, Patrick-Simon Welz, Geert van Loo (UGent) , Maria A Ermolaeva, Wilhelm Bloch, Ingo Haase and Manolis Pasparakis

(2011) IMMUNITY. 35(4). p.572-582
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FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation

Patrick-Simon Welz, Andy Wullaert (UGent) , Katerina Vlantis, Vangelis Kondylis, Vanesa Fernandez-Majada, Maria Ermolaeva, Petra Kirsch, Anja Sterner-Kock, Geert van Loo (UGent) and Manolis Pasparakis

(2011) NATURE. 477(7364). p.330-334
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Constitutive IKK2 activation in intestinal epithelial cells induces intestinal tumors in mice

Katerina Vlantis, Andy Wullaert (UGent) , Yoshiteru Sasaki, Marc Schmidt-Supprian, Klaus Rajewsky, Tania Roskams and Manolis Pasparakis

(2011) JOURNAL OF CLINICAL INVESTIGATION. 121(7). p.2781-2793
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NF-κB in the regulation of epithelial homeostasis and inflammation

Andy Wullaert (UGent) , Marion C Bonnet and Manolis Pasparakis

(2011) CELL RESEARCH. 21(1). p.146-158
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I kappa B kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-kappa B in the central nervous system

Jenni Raasch, Nicolas Zeller, Geert van Loo (UGent) , Doron Merkler, Alexander Mildner, Daniel Erny, Klaus-Peter Knobeloch, John R Bethea, Ari Waisman, Markus Knust, et al.

(2011) BRAIN. 134(4). p.1184-1198
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A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

Mourad Matmati (UGent) , Peggy Jacques (UGent) , Jonathan Maelfait (UGent) , Eveline Verheugen (UGent) , Mirjam Kool (UGent) , Mozes Sze (UGent) , Lies Geboes, Els Louagie (UGent) , Conor Mc Guire (UGent) , Lars Vereecke (UGent) , et al.

(2011) NATURE GENETICS. 43(9). p.908-U129
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A20 (TNFAIP3) deficiency in myeloid cells triggers rheumatoid arthritis

Dirk Elewaut (UGent) , Mourad Matmati (UGent) , Peggy Jacques (UGent) , Jonathan Maelfait (UGent) , Eveline Verheugen (UGent) , Mirjam Kool (UGent) , Mozes Sze (UGent) , Lies Geboes, Els Louagie (UGent) , Conor Mc Guire (UGent) , et al.

(2011) ANNALS OF THE RHEUMATIC DISEASES. 70(suppl. 2). p.A39-A40
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Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis

Lars Vereecke (UGent) , Mozes Sze (UGent) , Conor Mc Guire (UGent) , Brecht Rogiers (UGent) , Yuanyuan Chu, Marc Schmidt-Supprian, Manolis Pasparakis, Rudi Beyaert (UGent) and Geert van Loo (UGent)

(2010) JOURNAL OF EXPERIMENTAL MEDICINE. 207(7). p.1513-1523
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Oligodendrocyte-specific FADD deletion protects mice from autoimmune-mediated demyelination

Conor Mc Guire (UGent) , Thomas Volckaert (UGent) , Uta Wolke, Mozes Sze (UGent) , Riet De Rycke (UGent) , Ari Waisman, Marco Prinz, Rudi Beyaert (UGent) , Manolis Pasparakis and Geert van Loo (UGent)

(2010) JOURNAL OF IMMUNOLOGY. 185(12). p.7646-7653
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Generalized immune activation as a direct result of activated CD4+ T cell killing

Rute Marques, Adam Williams, Urszula Eksmond, Andy Wullaert (UGent) , Nigel Kileen, Manolis Pasparakis, Dimitris Kioussis and George Kassiotis

(2009) JOURNAL OF BIOLOGY. 8(10).
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Development of immunoglobulin lambda-chain-positive B cells, but not editing of immunoglobulin kappa-chain, depends on NF-kappa B signals

Emmanuel Derudder, Emily J. Cadera, J. Christoph Val, Jing Wang, Casey J. Fox, Shan Zha, Geert van Loo (UGent) , Manolis Pasparakis, Mark S. Schlissel, Marc Schmidt-Supprian, et al.

(2009) NATURE IMMUNOLOGY. 10(6). p.647-654
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Identification of oxidative stress and toll-like receptor 4 signaling as a key pathway of acute lung injury

Yumiko Imai, Keiji Kuba, G Greg Neely, Rubina Yaghubian-Malhami, Thomas Perkmann, Geert van Loo (UGent) , Maria Ermolaeva, Ruud Veldhuizen, YH Connie Leung, Hongliang Wang, et al.

(2008) CELL. 133(2). p.235-249
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Epithelial NEMO links innate immunity to chronic intestinal inflammation

Arianna Nenci, Christoph Becker, Andy Wullaert (UGent) , Ralph Gareus, Geert van Loo (UGent) , Silvio Danese, Marion Huth, Alexei Nikolaev, Clemens Neufert, Blair Madison, et al.

(2007) NATURE. 446(7135). p.557-561
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Deletion of NEMO/IKKγ in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma

Tom Luedde, Naiara Beraza, Vasileios Kotsikoris, Geert van Loo (UGent) , Arianna Nenci, Rita De Vos, Tania Roskams, Christian Trautwein and Manolis Pasparakis

(2007) CANCER CELL. 11(2). p.119-132
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Inhibition of transcription factor NF-κB in the central nervous system ameliorates autoimmune encephalomyelitis in mice

Geert van Loo (UGent) , Rossana De Lorenzi, Hauke Schmidt, Marion Huth, Alexander Mildner, Marc Schmidt-Supprian, Hans Lassmann, Marco R Prinz and Manolis Pasparakis

(2006) NATURE IMMUNOLOGY. 7(9). p.954-961

Academic Bibliography

Airway epithelial cell necroptosis contributes to asthma exacerbation in a mouse model of house dust mite-induced allergic inflammation

Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation

OTULIN prevents liver inflammation and hepatocellular carcinoma by inhibiting FADD- and RIPK1 kinase-mediated hepatocyte apoptosis

Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis

A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms

A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain

Molecular mechanisms of cell death : recommendations of the Nomenclature Committee on Cell Death 2018

TLR-independent anti-inflammatory function of intestinal epithelial TRAF6 signalling prevents DSS-induced colitis in mice

NEMO prevents RIP kinase 1-mediated epithelial cell death and chronic intestinal inflammation by NF-κB-dependent and -independent functions

Necroptosis and its role in inflammation

Synchronized renal tubular cell death involves ferroptosis

Bacteria regulate intestinal epithelial cell differentiation factors both in vitro and in vivo

A20 (Tnfaip3) deficiency in myeloid cells protects against influenza A virus infection

Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway

CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair

Conditional targeting of tumor necrosis factor receptor-associated factor 6 reveals opposing functions of toll-like receptor signaling in endothelial and myeloid cells in a mouse model of atherosclerosis

The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation

FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation

Constitutive IKK2 activation in intestinal epithelial cells induces intestinal tumors in mice

NF-κB in the regulation of epithelial homeostasis and inflammation

I kappa B kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-kappa B in the central nervous system

A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

A20 (TNFAIP3) deficiency in myeloid cells triggers rheumatoid arthritis

Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis

Oligodendrocyte-specific FADD deletion protects mice from autoimmune-mediated demyelination

Generalized immune activation as a direct result of activated CD4+ T cell killing

Development of immunoglobulin lambda-chain-positive B cells, but not editing of immunoglobulin kappa-chain, depends on NF-kappa B signals

Identification of oxidative stress and toll-like receptor 4 signaling as a key pathway of acute lung injury

Epithelial NEMO links innate immunity to chronic intestinal inflammation

Deletion of NEMO/IKKγ in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma

Inhibition of transcription factor NF-κB in the central nervous system ameliorates autoimmune encephalomyelitis in mice

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