Simultaneous targeting of IL-1 and IL-18 is required for protection against inflammatory and septic shock
2014) AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 189(3). p.282-291 Mark(
- Induction of apoptosis by TNF receptor 2 in a T-cell hybridoma is FADD dependent and blocked by caspase-8 inhibitors
- The caspase family
- The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity.
- TNF-induced intracellular signaling leading to gene induction or to cytotoxicity by necrosis or by apoptosis.