Advanced search
1 file | 735.52 KB

Quantitative dynamic 19F MRI oximetry in a phantom simulating hypoxia

Steven Baete (UGent) and Yves De Deene (UGent)
Author
Organization
Abstract
Tumor hypoxia is well known to reduce cancer treatment efficacy. Fluor-19 MRI oximetry can be used to map oxygen concentrations in hypoxic tissue. In this study a reproducible phantom which mimics oxygen consuming tissue is used for quantitative dynamic fluor-19 MRI oximetry. The phantom consists of a hemodialysis filter of which the outer compartment is filled with a gelatin matrix containing viable yeast cells and perfluorocarbon vesicles which simulate the absorption of perfluorocarbons from intravenous emulsions in tissue. The phantom can be used for hypoxia simulations and for validating computational biophysical models of hypoxia, as measured with fluor-19 MRI oximetry.

Downloads

  • (...).pdf
    • full text
    • |
    • UGent only
    • |
    • PDF
    • |
    • 735.52 KB

Citation

Please use this url to cite or link to this publication:

Chicago
Baete, Steven, and Yves De Deene. 2010. “Quantitative Dynamic 19F MRI Oximetry in a Phantom Simulating Hypoxia.” In Proceedings of the International Society for Magnetic Resonance in Medicine, 18:2745–2745.
APA
Baete, S., & De Deene, Y. (2010). Quantitative dynamic 19F MRI oximetry in a phantom simulating hypoxia. Proceedings of the International Society for Magnetic Resonance in Medicine (Vol. 18, pp. 2745–2745). Presented at the ISMRM 18th Scientific Meeting and Exhibition (ISMRM 2010).
Vancouver
1.
Baete S, De Deene Y. Quantitative dynamic 19F MRI oximetry in a phantom simulating hypoxia. Proceedings of the International Society for Magnetic Resonance in Medicine. 2010. p. 2745–2745.
MLA
Baete, Steven, and Yves De Deene. “Quantitative Dynamic 19F MRI Oximetry in a Phantom Simulating Hypoxia.” Proceedings of the International Society for Magnetic Resonance in Medicine. Vol. 18. 2010. 2745–2745. Print.
@inproceedings{956206,
  abstract     = {Tumor hypoxia is well known to reduce cancer treatment efficacy. Fluor-19 MRI oximetry can be used to map oxygen concentrations in hypoxic tissue. In this study a reproducible phantom which mimics oxygen consuming tissue is used for quantitative dynamic fluor-19 MRI oximetry. The phantom consists of a hemodialysis filter of which the outer compartment is filled with a gelatin matrix containing viable yeast cells and perfluorocarbon vesicles which simulate the absorption of perfluorocarbons from intravenous emulsions in tissue. The phantom can be used for hypoxia simulations and for validating computational biophysical models of hypoxia, as measured with fluor-19 MRI oximetry.},
  author       = {Baete, Steven and De Deene, Yves},
  booktitle    = {Proceedings of the International Society for Magnetic Resonance in Medicine},
  language     = {eng},
  location     = {Stockholm, Sweden},
  pages        = {2745--2745},
  title        = {Quantitative dynamic 19F MRI oximetry in a phantom simulating hypoxia},
  volume       = {18},
  year         = {2010},
}