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Linear gradient stationary phase optimized selectivity LC development and applications

Maarten De Beer UGent, Frederic Lynen UGent and Patrick Sandra UGent (2009) High Performance Liquid Phase Separations and Related Techniques, 34th International symposium, Abstracts.
abstract
Stationary phase optimised selectivity liquid chromatography (SOSLC) is a technique in RP-LC in order to tune the selectivity of separations by means of the stationary phase as parameter to be optimised. After optimisation, a tailor-made column can be obtained, existing out of a sequence of column segments of different stationary phases, whereby the retention times of the compounds and the selectivity are predicted. Originally, SOSLC was introduced as a tool that is only valid in isocratic analysis mode. Due to the drawback that isocratic analysis is intrinsic insufficient to separate complex mixtures of compounds, relatively differing in polarity, a new optimisation method and prediction algorithm is developed in order to apply the SOSLC principle in linear gradient mode. This new approach of gradient SOSLC is hereby presented and illustrated by means of a mixture of steroids.
Please use this url to cite or link to this publication:
author
organization
year
type
conference
publication status
published
subject
in
High Performance Liquid Phase Separations and Related Techniques, 34th International symposium, Abstracts
pages
? pages
conference name
34th International symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2009)
conference location
Dresden, Germany
conference start
2009-06-28
conference end
2009-07-02
language
English
UGent publication?
yes
classification
C3
id
956142
handle
http://hdl.handle.net/1854/LU-956142
date created
2010-05-27 13:38:28
date last changed
2010-06-22 10:25:12
@inproceedings{956142,
  abstract     = {Stationary phase optimised selectivity liquid chromatography (SOSLC) is a technique in RP-LC in order to tune the selectivity of separations by means of the stationary phase as parameter to be optimised. After optimisation, a tailor-made column can be obtained, existing out of a sequence of column segments of different stationary phases, whereby the retention times of the compounds and the selectivity are predicted. Originally, SOSLC was introduced as a tool that is only valid in isocratic analysis mode. Due to the drawback that isocratic analysis is intrinsic insufficient to separate complex mixtures of compounds, relatively differing in polarity, a new optimisation method and prediction algorithm is developed in order to apply the SOSLC principle in linear gradient mode. This new approach of gradient SOSLC is hereby presented and illustrated by means of a mixture of steroids.},
  author       = {De Beer, Maarten and Lynen, Frederic and Sandra, Patrick},
  booktitle    = {High Performance Liquid Phase Separations and Related Techniques, 34th International symposium, Abstracts},
  language     = {eng},
  location     = {Dresden, Germany},
  pages        = {?},
  title        = {Linear gradient stationary phase optimized selectivity LC development and applications},
  year         = {2009},
}

Chicago
De Beer, Maarten, Frederic Lynen, and Patrick Sandra. 2009. “Linear Gradient Stationary Phase Optimized Selectivity LC Development and Applications.” In High Performance Liquid Phase Separations and Related Techniques, 34th International Symposium, Abstracts.
APA
De Beer, M., Lynen, F., & Sandra, P. (2009). Linear gradient stationary phase optimized selectivity LC development and applications. High Performance Liquid Phase Separations and Related Techniques, 34th International symposium, Abstracts. Presented at the 34th International symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2009).
Vancouver
1.
De Beer M, Lynen F, Sandra P. Linear gradient stationary phase optimized selectivity LC development and applications. High Performance Liquid Phase Separations and Related Techniques, 34th International symposium, Abstracts. 2009.
MLA
De Beer, Maarten, Frederic Lynen, and Patrick Sandra. “Linear Gradient Stationary Phase Optimized Selectivity LC Development and Applications.” High Performance Liquid Phase Separations and Related Techniques, 34th International Symposium, Abstracts. 2009. Print.