Ghent University Academic Bibliography

Advanced

Progress in prevention of toxico-nutritional neurodegenerations

Fernand Lambein UGent, Delphin Diasolua Ngudi UGent and Yu-Haey Kuo UGent (2010) AFRICAN TECHNOLOGY DEVELOPMENT FORUM JOURNAL. 6(3-4). p.60-65
abstract
Grass pea (Lathyrus sativus) is a survival food during drought in Ethiopia and the Indian Subcontinent, producing the cheapest dietary protein and saving thousands of lives. It also is a mixed blessing as the cause of the crippling neurolathyrism after prolonged over-consumption. Cassava (Manihot esculenta) is a protein-poor root crop that is the staple food for over half a billion people in Africa, South America and Southeast Asia, and the cheapest source of dietary carbohydrates. Over-consumption of cassava roots in a monotonous diet can cause konzo, with clinical symptoms indistinguishable from neurolathyrism. The prominent features of both diseases are sudden onset of symmetric spastic paraparesis of the calf muscles and scissor gate. The common feature of grass pea seed and cassava roots is the low content of the essential sulphur containing amino acids methionine and cysteine. The focus of breeding has been the reduction of the neuro-excitatory amino acid b-ODAP (b-N-oxalyl-L-a,b-diaminopropionic acid) in grass pea and the reduction of the cyanogenic glucosides in cassava. Developing varieties with higher content in methionine and cysteine and a better balanced diet may be more relevant in improving nutrition without jeopardizing the tolerance for biotic and abiotic stress of these crops.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
journal title
AFRICAN TECHNOLOGY DEVELOPMENT FORUM JOURNAL
Afr. Technol. Dev. Forum J.
volume
6
issue
3-4
issue title
African orphan crops
pages
60 - 65
ISSN
1817-2008
language
English
UGent publication?
yes
classification
A4
copyright statement
I have transferred the copyright for this publication to the publisher
id
956125
handle
http://hdl.handle.net/1854/LU-956125
alternative location
http://www.atdforum.org/spip.php?article363
date created
2010-05-27 13:33:34
date last changed
2010-08-18 14:38:33
@article{956125,
  abstract     = {Grass pea (Lathyrus sativus) is a survival food during drought in Ethiopia and the Indian Subcontinent, producing the cheapest dietary protein and saving thousands of lives. It also is a mixed blessing as the cause of the crippling neurolathyrism after prolonged over-consumption. Cassava (Manihot esculenta) is a protein-poor root crop that is the staple food for over half a billion people in Africa, South America and Southeast Asia, and the cheapest source of dietary carbohydrates. Over-consumption of cassava roots in a monotonous diet can cause konzo, with clinical symptoms indistinguishable from neurolathyrism. The prominent features of both diseases are sudden onset of symmetric spastic paraparesis of the calf muscles and scissor gate. The common feature of grass pea seed and cassava roots is the low content of the essential sulphur containing amino acids methionine and cysteine. The focus of breeding has been the reduction of the neuro-excitatory amino acid b-ODAP (b-N-oxalyl-L-a,b-diaminopropionic acid) in grass pea and the reduction of the cyanogenic glucosides in cassava. Developing varieties with higher content in methionine and cysteine and a better balanced diet may be more relevant in improving nutrition without jeopardizing the tolerance for biotic and abiotic stress of these crops.},
  author       = {Lambein, Fernand and Diasolua Ngudi, Delphin and Kuo, Yu-Haey},
  issn         = {1817-2008},
  journal      = {AFRICAN TECHNOLOGY DEVELOPMENT FORUM JOURNAL},
  language     = {eng},
  number       = {3-4},
  pages        = {60--65},
  title        = {Progress in prevention of toxico-nutritional neurodegenerations},
  url          = {http://www.atdforum.org/spip.php?article363},
  volume       = {6},
  year         = {2010},
}

Chicago
Lambein, Fernand, Delphin Diasolua Ngudi, and Yu-Haey Kuo. 2010. “Progress in Prevention of Toxico-nutritional Neurodegenerations.” African Technology Development Forum Journal 6 (3-4): 60–65.
APA
Lambein, F., Diasolua Ngudi, D., & Kuo, Y.-H. (2010). Progress in prevention of toxico-nutritional neurodegenerations. AFRICAN TECHNOLOGY DEVELOPMENT FORUM JOURNAL, 6(3-4), 60–65.
Vancouver
1.
Lambein F, Diasolua Ngudi D, Kuo Y-H. Progress in prevention of toxico-nutritional neurodegenerations. AFRICAN TECHNOLOGY DEVELOPMENT FORUM JOURNAL. 2010;6(3-4):60–5.
MLA
Lambein, Fernand, Delphin Diasolua Ngudi, and Yu-Haey Kuo. “Progress in Prevention of Toxico-nutritional Neurodegenerations.” AFRICAN TECHNOLOGY DEVELOPMENT FORUM JOURNAL 6.3-4 (2010): 60–65. Print.