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Physiological and cognitive mediators for the association between self-reported depressed mood and impaired choice stepping reaction time in older people

Tasha Kvelde, Mirjam Pijnappels, Kim Delbaere UGent, Jacqueline CT Close and Stephen R Lord (2010) JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 65(5). p.538-544
abstract
Background. The aim of the study was to use path analysis to test a theoretical model proposing that the relationship between self-reported depressed mood and choice stepping reaction time (CSRT) is mediated by psychoactive medication use, physiological performance, and cognitive ability. Methods. A total of 280 retirement village residents, aged 62-95 years, undertook tests of CSRT, which required them to step onto one of four panels that were illuminated in a random order. Depressed mood was assessed using the 30-item Geriatric Depression Scale (GDS). The participants were also tested on physiological and cognitive performance, including quadriceps strength, balance, complex attention (Trail Making Test [TMT] B), simple reaction time, reported level of exercise, and use of psychoactive medications. Results. A total of 51 participants (18%) showed mild to severe depression. Those with higher GDS scores had significantly increased CSRT and worse performance on all physiological and cognitive parameters. CSRT was also significantly associated with all other measures. The final path analysis model revealed an association between self-reported depression and CSRT that was mediated by two paths, one through quadriceps strength and the other through TMT B with both mediating variables then influencing CSRT via simple reaction time and balance. Conclusions. The findings suggest that self-reported depressed mood is related to slowed performance on a CSRT task and that this relationship is explained by underlying physiological and cognitive impairments.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
GERIATRIC DEPRESSION, NURSING-HOME, RISK-FACTORS, RANDOMIZED CONTROLLED-TRIAL, Balance, Psychoactive medications, Exercise, Depression, Accidental falls, FALLS, PREVALENCE, DISABILITY, COMMUNITY, CARE, POPULATION
journal title
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
J. Gerontol. Ser. A-Biol. Sci. Med. Sci.
volume
65
issue
5
pages
538 - 544
Web of Science type
Article
Web of Science id
000277120700012
JCR category
GERONTOLOGY
JCR impact factor
3.988 (2010)
JCR rank
1/28 (2010)
JCR quartile
1 (2010)
ISSN
1079-5006
DOI
10.1093/gerona/glp195
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
953724
handle
http://hdl.handle.net/1854/LU-953724
date created
2010-05-27 06:06:26
date last changed
2010-09-21 13:53:09
@article{953724,
  abstract     = {Background. The aim of the study was to use path analysis to test a theoretical model proposing that the relationship between self-reported depressed mood and choice stepping reaction time (CSRT) is mediated by psychoactive medication use, physiological performance, and cognitive ability.
Methods. A total of 280 retirement village residents, aged 62-95 years, undertook tests of CSRT, which required them to step onto one of four panels that were illuminated in a random order. Depressed mood was assessed using the 30-item Geriatric Depression Scale (GDS). The participants were also tested on physiological and cognitive performance, including quadriceps strength, balance, complex attention (Trail Making Test [TMT] B), simple reaction time, reported level of exercise, and use of psychoactive medications.
Results. A total of 51 participants (18\%) showed mild to severe depression. Those with higher GDS scores had significantly increased CSRT and worse performance on all physiological and cognitive parameters. CSRT was also significantly associated with all other measures. The final path analysis model revealed an association between self-reported depression and CSRT that was mediated by two paths, one through quadriceps strength and the other through TMT B with both mediating variables then influencing CSRT via simple reaction time and balance.
Conclusions. The findings suggest that self-reported depressed mood is related to slowed performance on a CSRT task and that this relationship is explained by underlying physiological and cognitive impairments.},
  author       = {Kvelde, Tasha and Pijnappels, Mirjam and Delbaere, Kim and Close, Jacqueline CT and Lord, Stephen R},
  issn         = {1079-5006},
  journal      = {JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES},
  keyword      = {GERIATRIC DEPRESSION,NURSING-HOME,RISK-FACTORS,RANDOMIZED CONTROLLED-TRIAL,Balance,Psychoactive medications,Exercise,Depression,Accidental falls,FALLS,PREVALENCE,DISABILITY,COMMUNITY,CARE,POPULATION},
  language     = {eng},
  number       = {5},
  pages        = {538--544},
  title        = {Physiological and cognitive mediators for the association between self-reported depressed mood and impaired choice stepping reaction time in older people},
  url          = {http://dx.doi.org/10.1093/gerona/glp195},
  volume       = {65},
  year         = {2010},
}

Chicago
Kvelde, Tasha, Mirjam Pijnappels, Kim Delbaere, Jacqueline CT Close, and Stephen R Lord. 2010. “Physiological and Cognitive Mediators for the Association Between Self-reported Depressed Mood and Impaired Choice Stepping Reaction Time in Older People.” Journals of Gerontology Series A-biological Sciences and Medical Sciences 65 (5): 538–544.
APA
Kvelde, T., Pijnappels, M., Delbaere, K., Close, J. C., & Lord, S. R. (2010). Physiological and cognitive mediators for the association between self-reported depressed mood and impaired choice stepping reaction time in older people. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 65(5), 538–544.
Vancouver
1.
Kvelde T, Pijnappels M, Delbaere K, Close JC, Lord SR. Physiological and cognitive mediators for the association between self-reported depressed mood and impaired choice stepping reaction time in older people. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2010;65(5):538–44.
MLA
Kvelde, Tasha, Mirjam Pijnappels, Kim Delbaere, et al. “Physiological and Cognitive Mediators for the Association Between Self-reported Depressed Mood and Impaired Choice Stepping Reaction Time in Older People.” JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 65.5 (2010): 538–544. Print.