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Control of Clostridium perfringens-induced necrotic enteritis in broilers by target-released butyric acid, fatty acids and essential oils

Leen Timbermont UGent, Anouk Lanckriet UGent, Jeroen Dewulf UGent, Nathalie Nollet, Koen Schwarzer, Freddy Haesebrouck UGent, Richard Ducatelle UGent and Filip Van Immerseel UGent (2010) AVIAN PATHOLOGY. 39(2). p.117-121
abstract
The efficacy of target-released butyric acid, medium-chain fatty acids (C6 to C12 but mainly lauric acid) and essential oils (thymol, cinnamaldehyde, essential oil of eucalyptus) micro-encapsulated in a poly-sugar matrix to control necrotic enteritis was investigated. The minimal inhibitory concentrations of the different additives were determined in vitro, showing that lauric acid, thymol, and cinnamaldehyde are very effective in inhibiting the growth of Clostridium perfringens. The in vivo effects were studied in two trials in an experimental necrotic enteritis model in broiler chickens. In the first trial, four groups of chickens were fed a diet supplemented with butyric acid, with essential oils, with butyric acid in combination with medium-chain fatty acids, or with butyric acid in combination with medium-chain fatty acids and essential oils. In all groups except for the group receiving only butyric acid, a significant decrease in the number of birds with necrotic lesions was found compared with the infected, untreated control group. In the trial the same products were tested but at a higher concentration. An additional group was fed a diet supplemented with only medium-chain fatty acids. In all groups except for that receiving butyric acid in combination with medium-chain fatty acids and essential oils, a significant decrease in the number of birds with necrotic lesions was found compared with the infected, untreated control group. These results suggest that butyric acid, medium-chain fatty acids and/or essential oils may contribute to the prevention of necrotic enteritis in broilers.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
necrotic enteritis, medium chain fatty acids, butyric acid, Clostridium perfringens, essential oils, CHICKENS, PERFORMANCE, POULTRY, SUSCEPTIBILITY, PROLIFERATION, DIGESTIBILITY, EXPRESSION, EXTRACTS, ANIMALS, NORWAY
journal title
AVIAN PATHOLOGY
Avian Pathol.
volume
39
issue
2
pages
117 - 121
Web of Science type
Article
Web of Science id
000276461500007
JCR category
VETERINARY SCIENCES
JCR impact factor
1.967 (2010)
JCR rank
16/145 (2010)
JCR quartile
1 (2010)
ISSN
0307-9457
DOI
10.1080/03079451003610586
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
909907
handle
http://hdl.handle.net/1854/LU-909907
date created
2010-03-22 09:47:20
date last changed
2011-07-07 15:26:07
@article{909907,
  abstract     = {The efficacy of target-released butyric acid, medium-chain fatty acids (C6 to C12 but mainly lauric acid) and essential oils (thymol, cinnamaldehyde, essential oil of eucalyptus) micro-encapsulated in a poly-sugar matrix to control necrotic enteritis was investigated. The minimal inhibitory concentrations of the different additives were determined in vitro, showing that lauric acid, thymol, and cinnamaldehyde are very effective in inhibiting the growth of Clostridium perfringens. The in vivo effects were studied in two trials in an experimental necrotic enteritis model in broiler chickens. In the first trial, four groups of chickens were fed a diet supplemented with butyric acid, with essential oils, with butyric acid in combination with medium-chain fatty acids, or with butyric acid in combination with medium-chain fatty acids and essential oils. In all groups except for the group receiving only butyric acid, a significant decrease in the number of birds with necrotic lesions was found compared with the infected, untreated control group. In the trial the same products were tested but at a higher concentration. An additional group was  fed a diet supplemented with only medium-chain fatty acids. In all groups except for that receiving butyric acid in combination with medium-chain fatty acids and essential oils, a significant decrease in the number of birds with necrotic lesions was found compared with the infected, untreated control group. These results suggest that butyric acid, medium-chain fatty acids and/or essential oils may contribute to the prevention of necrotic enteritis in broilers.},
  author       = {Timbermont, Leen and Lanckriet, Anouk and Dewulf, Jeroen and Nollet, Nathalie and Schwarzer, Koen and Haesebrouck, Freddy and Ducatelle, Richard and Van Immerseel, Filip},
  issn         = {0307-9457},
  journal      = {AVIAN PATHOLOGY},
  keyword      = {necrotic enteritis,medium chain fatty acids,butyric acid,Clostridium perfringens,essential oils,CHICKENS,PERFORMANCE,POULTRY,SUSCEPTIBILITY,PROLIFERATION,DIGESTIBILITY,EXPRESSION,EXTRACTS,ANIMALS,NORWAY},
  language     = {eng},
  number       = {2},
  pages        = {117--121},
  title        = {Control of Clostridium perfringens-induced necrotic enteritis in broilers by target-released butyric acid, fatty acids and essential oils},
  url          = {http://dx.doi.org/10.1080/03079451003610586},
  volume       = {39},
  year         = {2010},
}

Chicago
Timbermont, Leen, Anouk Lanckriet, Jeroen Dewulf, Nathalie Nollet, Koen Schwarzer, Freddy Haesebrouck, Richard Ducatelle, and Filip Van Immerseel. 2010. “Control of Clostridium Perfringens-induced Necrotic Enteritis in Broilers by Target-released Butyric Acid, Fatty Acids and Essential Oils.” Avian Pathology 39 (2): 117–121.
APA
Timbermont, L., Lanckriet, A., Dewulf, J., Nollet, N., Schwarzer, K., Haesebrouck, F., Ducatelle, R., et al. (2010). Control of Clostridium perfringens-induced necrotic enteritis in broilers by target-released butyric acid, fatty acids and essential oils. AVIAN PATHOLOGY, 39(2), 117–121.
Vancouver
1.
Timbermont L, Lanckriet A, Dewulf J, Nollet N, Schwarzer K, Haesebrouck F, et al. Control of Clostridium perfringens-induced necrotic enteritis in broilers by target-released butyric acid, fatty acids and essential oils. AVIAN PATHOLOGY. 2010;39(2):117–21.
MLA
Timbermont, Leen, Anouk Lanckriet, Jeroen Dewulf, et al. “Control of Clostridium Perfringens-induced Necrotic Enteritis in Broilers by Target-released Butyric Acid, Fatty Acids and Essential Oils.” AVIAN PATHOLOGY 39.2 (2010): 117–121. Print.