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Occurrence of mycotoxins in feed as analyzed by a multi-mycotoxin LC-MS/MS method

Sofie Monbaliu, Christof Van Poucke, Christel Detavernier UGent, Frédéric Dumoulin UGent, Mario Van de Velde UGent, Elke Schoeters, Stefaan Van Dyck, Olga Averkieva, Carlos Van Peteghem and Sarah De Saeger UGent (2010) JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 58(1). p.66-71
abstract
Crops used for animal feed can be easily contaminated by fungi during growth, harvest, or storage, resulting in the occurrence of mycotoxins. Because animal feed plays an important role in the food safety chain, the European Commission has set maximum levels for aflatoxin B-1 and recommended maximum levels for deoxynivalenol, zearalenone, ochratoxin A, and the sum of fumonisin B-1 and B-2. A multimycotoxin LC-MS/MS method was developed, validated according to Commission Decision 2002/657/EC and EN ISO 17025 accredited for the simultaneous detection of 23 mycotoxins (aflatoxin-B-1, aflatoxin-B-2, aflatoxin-G(1), aflatoxin-G(2), ochratoxin A, deoxynivalenol, zearalenone, fumonisin B-1, fumonisin B-2, fumonisin B-3, T2-toxin, HT2-toxin, nivalenol, 3-acetyldeoxynivalenol, 15-acetyldeoxynivalenol, diacetoxyscirpenol, fusarenon-X, neosolaniol, aftenuene, alternariol, alternariol methyl ether, roquefortine-C, and sterigmatocystin) in feed. The decision limits of the multimycotoxin method varied from 0.7 to 60.6 mu g/kg. The apparent recovery and the results of the precision study fulfilled the performance criteria as set in Commission Decision 2002/657/EC. The analysis of three different feed matrices (sow feed, wheat, and maize) provided a good basis for the evaluation of the toxin exposure in animal production. In total, 67 samples out of 82 (82%) were contaminated; type B-trichothecenes and fumonisins occurred most often. The majority of the infected feed samples (75%) were contaminated with more than one type of mycotoxin.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
AFLATOXIN, DEOXYNIVALENOL, GRAINS, validation, feed analysis, multimycotoxin, LC-MS/MS, FOOD MATRICES, T-2 TOXIN, BROILER-CHICKENS, MASS-SPECTROMETRY
journal title
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
J. Agric. Food Chem.
volume
58
issue
1
pages
6 pages
Web of Science type
Article
Web of Science id
000273268100007
JCR category
AGRICULTURE, MULTIDISCIPLINARY
JCR impact factor
2.816 (2010)
JCR rank
2/55 (2010)
JCR quartile
1 (2010)
ISSN
0021-8561
DOI
10.1021/jf903859z
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
898397
handle
http://hdl.handle.net/1854/LU-898397
date created
2010-03-08 16:49:27
date last changed
2016-12-19 15:46:13
@article{898397,
  abstract     = {Crops used for animal feed can be easily contaminated by fungi during growth, harvest, or storage, resulting in the occurrence of mycotoxins. Because animal feed plays an important role in the food safety chain, the European Commission has set maximum levels for aflatoxin B-1 and recommended maximum levels for deoxynivalenol, zearalenone, ochratoxin A, and the sum of fumonisin B-1 and B-2. A multimycotoxin LC-MS/MS method was developed, validated according to Commission Decision 2002/657/EC and EN ISO 17025 accredited for the simultaneous detection of 23 mycotoxins (aflatoxin-B-1, aflatoxin-B-2, aflatoxin-G(1), aflatoxin-G(2), ochratoxin A, deoxynivalenol, zearalenone, fumonisin B-1, fumonisin B-2, fumonisin B-3, T2-toxin, HT2-toxin, nivalenol, 3-acetyldeoxynivalenol, 15-acetyldeoxynivalenol, diacetoxyscirpenol, fusarenon-X, neosolaniol, aftenuene, alternariol, alternariol methyl ether, roquefortine-C, and sterigmatocystin) in feed. The decision limits of the multimycotoxin method varied from 0.7 to 60.6 mu g/kg. The apparent recovery and the results of the precision study fulfilled the performance criteria as set in Commission Decision 2002/657/EC. The analysis of three different feed matrices (sow feed, wheat, and maize) provided a good basis for the evaluation of the toxin exposure in animal production. In total, 67 samples out of 82 (82\%) were contaminated; type B-trichothecenes and fumonisins occurred most often. The majority of the infected feed samples (75\%) were contaminated with more than one type of mycotoxin.},
  author       = {Monbaliu, Sofie and Van Poucke, Christof and Detavernier, Christel and Dumoulin, Fr{\'e}d{\'e}ric and Van de Velde, Mario and Schoeters, Elke and Van Dyck, Stefaan and Averkieva, Olga and Van Peteghem, Carlos and De Saeger, Sarah},
  issn         = {0021-8561},
  journal      = {JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY},
  keyword      = {AFLATOXIN,DEOXYNIVALENOL,GRAINS,validation,feed analysis,multimycotoxin,LC-MS/MS,FOOD MATRICES,T-2 TOXIN,BROILER-CHICKENS,MASS-SPECTROMETRY},
  language     = {eng},
  number       = {1},
  pages        = {66--71},
  title        = {Occurrence of mycotoxins in feed as analyzed by a multi-mycotoxin LC-MS/MS method},
  url          = {http://dx.doi.org/10.1021/jf903859z},
  volume       = {58},
  year         = {2010},
}

Chicago
Monbaliu, Sofie, Christof Van Poucke, Christel Detavernier, Frédéric Dumoulin, Mario Van de Velde, Elke Schoeters, Stefaan Van Dyck, Olga Averkieva, Carlos Van Peteghem, and Sarah De Saeger. 2010. “Occurrence of Mycotoxins in Feed as Analyzed by a Multi-mycotoxin LC-MS/MS Method.” Journal of Agricultural and Food Chemistry 58 (1): 66–71.
APA
Monbaliu, S., Van Poucke, C., Detavernier, C., Dumoulin, F., Van de Velde, M., Schoeters, E., Van Dyck, S., et al. (2010). Occurrence of mycotoxins in feed as analyzed by a multi-mycotoxin LC-MS/MS method. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 58(1), 66–71.
Vancouver
1.
Monbaliu S, Van Poucke C, Detavernier C, Dumoulin F, Van de Velde M, Schoeters E, et al. Occurrence of mycotoxins in feed as analyzed by a multi-mycotoxin LC-MS/MS method. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 2010;58(1):66–71.
MLA
Monbaliu, Sofie, Christof Van Poucke, Christel Detavernier, et al. “Occurrence of Mycotoxins in Feed as Analyzed by a Multi-mycotoxin LC-MS/MS Method.” JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 58.1 (2010): 66–71. Print.