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Bioavailability of phytoestrogens from soy and hops

Selin Bolca (UGent), Sam Possemiers (UGent), Arne Heyerick (UGent), Denis De Keukeleire (UGent), Herman Depypere (UGent), Marc Bracke (UGent), Inge Huybrechts (UGent), Stefaan De Henauw (UGent) and Willy Verstraete (UGent)
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Abstract
Phytoestrogens are plant constituents which possess pro- and antiestrogenic properties and are therefore considered to play a beneficial role in the prevention of hormone related disorders. Soy is the major dietary source of phytoestrogens and hops contain the most potent phytoestrogen. The microbial metabolism is important for the bioactivity of the ingested phytoestrogens. There is a large interindividual variation in the metabolism partially due to the interindividual differences in activity and composition of the gut microbiota. The factors influencing the microbial metabolism are still largely unknown. A randomized intervention study with 150 healthy menopausal women was undertaken. Exclusion criteria were hormone replacement therapy, allergy to soy products and the use of antibiotics up to 3 month before the study. After a 4-day washout period, all participants delivered a fecal sample for incubation purposes and microbiological characterization, a control urine sample, and filled a gas collection bag for methane analysis. Participants ingested a soy or hop extract or 250 mL soymilk 3 times a day for 5 consecutive days. A 24-h urine sample of the fifth day was collected. Subjects consumed their habitual diets but were asked to avoid all products based on soy or hops during the study. A food frequency questionnaire was used to elicit the usual fat and fiber consumption.

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Chicago
Bolca, Selin, Sam Possemiers, Arne Heyerick, Denis De Keukeleire, Herman Depypere, Marc Bracke, Inge Huybrechts, Stefaan De Henauw, and Willy Verstraete. 2006. “Bioavailability of Phytoestrogens from Soy and Hops.” In Reproduction Nutrition Development, 46:S87.
APA
Bolca, S., Possemiers, S., Heyerick, A., De Keukeleire, D., Depypere, H., Bracke, M., Huybrechts, I., et al. (2006). Bioavailability of phytoestrogens from soy and hops. Reproduction Nutrition Development (Vol. 46, p. S87). Presented at the 5th joint RRI-INRA Gastrointestinal Tract Microbiology Symposium “Gut Microbiology: Research to improve health, immune response and nutrition.”
Vancouver
1.
Bolca S, Possemiers S, Heyerick A, De Keukeleire D, Depypere H, Bracke M, et al. Bioavailability of phytoestrogens from soy and hops. Reproduction Nutrition Development. 2006. p. S87.
MLA
Bolca, Selin, Sam Possemiers, Arne Heyerick, et al. “Bioavailability of Phytoestrogens from Soy and Hops.” Reproduction Nutrition Development. Vol. 46. 2006. S87. Print.
@inproceedings{878133,
  abstract     = {Phytoestrogens are plant constituents which
possess pro- and antiestrogenic properties and
are therefore considered to play a beneficial role
in the prevention of hormone related disorders.
Soy is the major dietary source of phytoestrogens
and hops contain the most potent phytoestrogen.
The microbial metabolism is important
for the bioactivity of the ingested phytoestrogens.
There is a large interindividual variation in
the metabolism partially due to the interindividual
differences in activity and composition of the
gut microbiota. The factors influencing the
microbial metabolism are still largely unknown.
A randomized intervention study with 150 healthy
menopausal women was undertaken. Exclusion
criteria were hormone replacement therapy,
allergy to soy products and the use of antibiotics
up to 3 month before the study. After a 4-day
washout period, all participants delivered a fecal
sample for incubation purposes and microbiological
characterization, a control urine sample,
and filled a gas collection bag for methane analysis.
Participants ingested a soy or hop extract
or 250 mL soymilk 3 times a day for 5 consecutive
days. A 24-h urine sample of the fifth day
was collected. Subjects consumed their habitual
diets but were asked to avoid all products based
on soy or hops during the study. A food frequency
questionnaire was used to elicit the usual
fat and fiber consumption.},
  author       = {Bolca, Selin and Possemiers, Sam and Heyerick, Arne and De Keukeleire, Denis and Depypere, Herman and Bracke, Marc and Huybrechts, Inge and De Henauw, Stefaan and Verstraete, Willy},
  booktitle    = {Reproduction Nutrition Development},
  issn         = {0926-5287},
  language     = {eng},
  location     = {University of Aberdeen, Scotland, UK},
  number       = {S1},
  title        = {Bioavailability of phytoestrogens from soy and hops},
  volume       = {46},
  year         = {2006},
}