Growth and remodeling in the pulmonary autograft : computational evaluation using kinematic growth models and constrained mixture theory
- Author
- Julie Vastmans, Lauranne Maes, Mathias Peirlinck (UGent) , Emma Vanderveken, Filip Rega, Ellen Kuhl and Nele Famaey
- Organization
- Abstract
- Computational investigations of how soft tissues grow and remodel are gaining more and more interest and several growth and remodeling theories have been developed. Roughly, two main groups of theories for soft tissues can be distinguished: kinematic-based growth theory and theories based on constrained mixture theory. Our goal was to apply these two theories on the same experimental data. Within the experiment, a pulmonary artery was exposed to systemic conditions. The change in diameter was followed-up over time. A mechanical and microstructural analysis of native pulmonary artery and pulmonary autograft was conducted. Whereas the kinematic-based growth theory is able to accurately capture the growth of the tissue, it does not account for the mechanobiological processes causing this growth. The constrained mixture theory takes into account the mechanobiological processes including removal, deposition and adaptation of all structural constituents, allowing us to simulate a changing microstructure and mechanical behavior.
- Keywords
- ARTERIAL, MECHANOBIOLOGY, IMPLEMENTATION, ADAPTATION, MECHANICS, COLLAGEN, AORTA, constrained mixture theory, growth and remodeling models, kinematic, growth, pulmonary autograft
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-8763196
- MLA
- Vastmans, Julie, et al. “Growth and Remodeling in the Pulmonary Autograft : Computational Evaluation Using Kinematic Growth Models and Constrained Mixture Theory.” INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING, vol. 38, no. 1, 2022, doi:10.1002/cnm.3545.
- APA
- Vastmans, J., Maes, L., Peirlinck, M., Vanderveken, E., Rega, F., Kuhl, E., & Famaey, N. (2022). Growth and remodeling in the pulmonary autograft : computational evaluation using kinematic growth models and constrained mixture theory. INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING, 38(1). https://doi.org/10.1002/cnm.3545
- Chicago author-date
- Vastmans, Julie, Lauranne Maes, Mathias Peirlinck, Emma Vanderveken, Filip Rega, Ellen Kuhl, and Nele Famaey. 2022. “Growth and Remodeling in the Pulmonary Autograft : Computational Evaluation Using Kinematic Growth Models and Constrained Mixture Theory.” INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING 38 (1). https://doi.org/10.1002/cnm.3545.
- Chicago author-date (all authors)
- Vastmans, Julie, Lauranne Maes, Mathias Peirlinck, Emma Vanderveken, Filip Rega, Ellen Kuhl, and Nele Famaey. 2022. “Growth and Remodeling in the Pulmonary Autograft : Computational Evaluation Using Kinematic Growth Models and Constrained Mixture Theory.” INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING 38 (1). doi:10.1002/cnm.3545.
- Vancouver
- 1.Vastmans J, Maes L, Peirlinck M, Vanderveken E, Rega F, Kuhl E, et al. Growth and remodeling in the pulmonary autograft : computational evaluation using kinematic growth models and constrained mixture theory. INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING. 2022;38(1).
- IEEE
- [1]J. Vastmans et al., “Growth and remodeling in the pulmonary autograft : computational evaluation using kinematic growth models and constrained mixture theory,” INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING, vol. 38, no. 1, 2022.
@article{8763196,
abstract = {{Computational investigations of how soft tissues grow and remodel are gaining more and more interest and several growth and remodeling theories have been developed. Roughly, two main groups of theories for soft tissues can be distinguished: kinematic-based growth theory and theories based on constrained mixture theory. Our goal was to apply these two theories on the same experimental data. Within the experiment, a pulmonary artery was exposed to systemic conditions. The change in diameter was followed-up over time. A mechanical and microstructural analysis of native pulmonary artery and pulmonary autograft was conducted. Whereas the kinematic-based growth theory is able to accurately capture the growth of the tissue, it does not account for the mechanobiological processes causing this growth. The constrained mixture theory takes into account the mechanobiological processes including removal, deposition and adaptation of all structural constituents, allowing us to simulate a changing microstructure and mechanical behavior.}},
articleno = {{e3545}},
author = {{Vastmans, Julie and Maes, Lauranne and Peirlinck, Mathias and Vanderveken, Emma and Rega, Filip and Kuhl, Ellen and Famaey, Nele}},
issn = {{2040-7939}},
journal = {{INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING}},
keywords = {{ARTERIAL,MECHANOBIOLOGY,IMPLEMENTATION,ADAPTATION,MECHANICS,COLLAGEN,AORTA,constrained mixture theory,growth and remodeling models,kinematic,growth,pulmonary autograft}},
language = {{eng}},
number = {{1}},
pages = {{24}},
title = {{Growth and remodeling in the pulmonary autograft : computational evaluation using kinematic growth models and constrained mixture theory}},
url = {{http://doi.org/10.1002/cnm.3545}},
volume = {{38}},
year = {{2022}},
}
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