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Pneumonia severity index compared to CURB-65 in predicting the outcome of community acquired pneumonia among patients referred to an Iranian emergency department : a prospective survey

Mostafa Alavi-Moghaddam, Hooman Bakhshi, Bareza Rezaei and Patricia Khashayar (UGent)
(2013) BRAZILIAN JOURNAL OF INFECTIOUS DISEASES. 17(2). p.179-183
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Organization
Abstract
Objective: To compare the prognostic value of the pneumonia severity index and the severity score for community-acquired pneumonia (CURB-65) in predicting mortality and the need for ICU admission of patients with community-acquired pneumonia referred to our emergency department. Materials and methods: This prospective study was performed on patients with community-acquired pneumonia admitted to the emergency department of Imam Hossein Medical Center, Tehran, Iran. A questionnaire with demographic information, clinical signs and symptoms, laboratory and radiographic findings was completed for each patient. The information required for calculating the pneumonia severity index and CURB-65 were extracted from the medical records. The patients' clinical outcome was also recorded within a month after admission. Results: We studied 200 patients with community-acquired pneumonia (122 men, 78 women). The sensitivity and specificity of CURB-65 in predicting mortality were 100% and 82.3%, respectively. As for pneumonia severity index, the rates were 100% and 75%, respectively. The sensitivity and specificity rates of CURB-65 and pneumonia severity index in predicting mortality and need for ICU admission were 96.7% and 89.3%, and 90% and 78.7%, respectively. Conclusion: CURB-65 seems to be the preferred method to predict mortality and need for ICU admission in patients with community-acquired pneumonia. Despite their comparable specificity and sensitivity, CURB-65 is much easier to implement. (C) 2013 Elsevier Editora Ltda. All rights reserved.
Keywords
Infectious Diseases, Microbiology (medical), CURB-65, PSI, Community-acquired pneumonia, VALIDATION, RULE, DERIVATION

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MLA
Alavi-Moghaddam, Mostafa, et al. “Pneumonia Severity Index Compared to CURB-65 in Predicting the Outcome of Community Acquired Pneumonia among Patients Referred to an Iranian Emergency Department : A Prospective Survey.” BRAZILIAN JOURNAL OF INFECTIOUS DISEASES, vol. 17, no. 2, 2013, pp. 179–83, doi:10.1016/j.bjid.2012.10.012.
APA
Alavi-Moghaddam, M., Bakhshi, H., Rezaei, B., & Khashayar, P. (2013). Pneumonia severity index compared to CURB-65 in predicting the outcome of community acquired pneumonia among patients referred to an Iranian emergency department : a prospective survey. BRAZILIAN JOURNAL OF INFECTIOUS DISEASES, 17(2), 179–183. https://doi.org/10.1016/j.bjid.2012.10.012
Chicago author-date
Alavi-Moghaddam, Mostafa, Hooman Bakhshi, Bareza Rezaei, and Patricia Khashayar. 2013. “Pneumonia Severity Index Compared to CURB-65 in Predicting the Outcome of Community Acquired Pneumonia among Patients Referred to an Iranian Emergency Department : A Prospective Survey.” BRAZILIAN JOURNAL OF INFECTIOUS DISEASES 17 (2): 179–83. https://doi.org/10.1016/j.bjid.2012.10.012.
Chicago author-date (all authors)
Alavi-Moghaddam, Mostafa, Hooman Bakhshi, Bareza Rezaei, and Patricia Khashayar. 2013. “Pneumonia Severity Index Compared to CURB-65 in Predicting the Outcome of Community Acquired Pneumonia among Patients Referred to an Iranian Emergency Department : A Prospective Survey.” BRAZILIAN JOURNAL OF INFECTIOUS DISEASES 17 (2): 179–183. doi:10.1016/j.bjid.2012.10.012.
Vancouver
1.
Alavi-Moghaddam M, Bakhshi H, Rezaei B, Khashayar P. Pneumonia severity index compared to CURB-65 in predicting the outcome of community acquired pneumonia among patients referred to an Iranian emergency department : a prospective survey. BRAZILIAN JOURNAL OF INFECTIOUS DISEASES. 2013;17(2):179–83.
IEEE
[1]
M. Alavi-Moghaddam, H. Bakhshi, B. Rezaei, and P. Khashayar, “Pneumonia severity index compared to CURB-65 in predicting the outcome of community acquired pneumonia among patients referred to an Iranian emergency department : a prospective survey,” BRAZILIAN JOURNAL OF INFECTIOUS DISEASES, vol. 17, no. 2, pp. 179–183, 2013.
@article{8735375,
  abstract     = {{Objective: To compare the prognostic value of the pneumonia severity index and the severity score for community-acquired pneumonia (CURB-65) in predicting mortality and the need for ICU admission of patients with community-acquired pneumonia referred to our emergency department.

Materials and methods: This prospective study was performed on patients with community-acquired pneumonia admitted to the emergency department of Imam Hossein Medical Center, Tehran, Iran. A questionnaire with demographic information, clinical signs and symptoms, laboratory and radiographic findings was completed for each patient. The information required for calculating the pneumonia severity index and CURB-65 were extracted from the medical records. The patients' clinical outcome was also recorded within a month after admission.

Results: We studied 200 patients with community-acquired pneumonia (122 men, 78 women). The sensitivity and specificity of CURB-65 in predicting mortality were 100% and 82.3%, respectively. As for pneumonia severity index, the rates were 100% and 75%, respectively. The sensitivity and specificity rates of CURB-65 and pneumonia severity index in predicting mortality and need for ICU admission were 96.7% and 89.3%, and 90% and 78.7%, respectively. 

Conclusion: CURB-65 seems to be the preferred method to predict mortality and need for ICU admission in patients with community-acquired pneumonia. Despite their comparable specificity and sensitivity, CURB-65 is much easier to implement. (C) 2013 Elsevier Editora Ltda. All rights reserved.}},
  author       = {{Alavi-Moghaddam, Mostafa and Bakhshi, Hooman and Rezaei, Bareza and Khashayar, Patricia}},
  issn         = {{1413-8670}},
  journal      = {{BRAZILIAN JOURNAL OF INFECTIOUS DISEASES}},
  keywords     = {{Infectious Diseases,Microbiology (medical),CURB-65,PSI,Community-acquired pneumonia,VALIDATION,RULE,DERIVATION}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{179--183}},
  title        = {{Pneumonia severity index compared to CURB-65 in predicting the outcome of community acquired pneumonia among patients referred to an Iranian emergency department : a prospective survey}},
  url          = {{http://doi.org/10.1016/j.bjid.2012.10.012}},
  volume       = {{17}},
  year         = {{2013}},
}
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