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Should I, can I, dare I? Patients’ view on stopping long-term antidepressant use, a qualitative study

(2022) ACTA CLINICA BELGICA. 77(6). p.962-969
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Abstract
Background and aim The rise in long-term antidepressant use is concerning. Long-term antidepressant (AD) use, much longer than recommended by guidelines, can result in risk of adverse events and generate unnecessary costs. In order to mitigate these risks, patients views about their antidepressants and how to discontinue need to be taken into account. We aimed to explore patients' experiences and views of discontinuing long-term AD, barriers and facilitators of discontinuation and required support. Methods Semi-structured face to face interviews were conducted with 14 patients with long-term AD use in primary care. Interviews were analysed thematically. Results Participants describe various perceptions about discontinuation. There is fear of returning to their depression, even in those who were ambivalent about the effectiveness and safety of AD continuation. Participants describe low confidence in their own coping resources, fear of stress, and previous negative experiences with stopping. This enhances their perception of AD dependence. Participants indicate the importance of the support of their GP and their social network to help them withdraw. Conclusion Discontinuation of long-term antidepressants is a complex issue for patients. More awareness of the lack of evidence and the potential risks of long-term AD continuation is required. By raising the issue and offering support during discontinuation GPs can help their patients stop AD. A greater focus on non-pharmacological approaches of depression in primary care is needed to reduce unnecessary AD use.
Keywords
General Medicine, Antidepressant discontinuation, depression, general practice, long-term antidepressant use, qualitative research, PERSPECTIVES, HEALTH

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Citation

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MLA
Van Leeuwen, Ellen, et al. “Should I, Can I, Dare I? Patients’ View on Stopping Long-Term Antidepressant Use, a Qualitative Study.” ACTA CLINICA BELGICA, vol. 77, no. 6, 2022, pp. 962–69, doi:10.1080/17843286.2021.2024384.
APA
Van Leeuwen, E., Anthierens, S., van Driel, M., De Sutter, A., De Beir, R., & Christiaens, T. (2022). Should I, can I, dare I? Patients’ view on stopping long-term antidepressant use, a qualitative study. ACTA CLINICA BELGICA, 77(6), 962–969. https://doi.org/10.1080/17843286.2021.2024384
Chicago author-date
Van Leeuwen, Ellen, Sibyl Anthierens, Mieke van Driel, An De Sutter, Rani De Beir, and Thierry Christiaens. 2022. “Should I, Can I, Dare I? Patients’ View on Stopping Long-Term Antidepressant Use, a Qualitative Study.” ACTA CLINICA BELGICA 77 (6): 962–69. https://doi.org/10.1080/17843286.2021.2024384.
Chicago author-date (all authors)
Van Leeuwen, Ellen, Sibyl Anthierens, Mieke van Driel, An De Sutter, Rani De Beir, and Thierry Christiaens. 2022. “Should I, Can I, Dare I? Patients’ View on Stopping Long-Term Antidepressant Use, a Qualitative Study.” ACTA CLINICA BELGICA 77 (6): 962–969. doi:10.1080/17843286.2021.2024384.
Vancouver
1.
Van Leeuwen E, Anthierens S, van Driel M, De Sutter A, De Beir R, Christiaens T. Should I, can I, dare I? Patients’ view on stopping long-term antidepressant use, a qualitative study. ACTA CLINICA BELGICA. 2022;77(6):962–9.
IEEE
[1]
E. Van Leeuwen, S. Anthierens, M. van Driel, A. De Sutter, R. De Beir, and T. Christiaens, “Should I, can I, dare I? Patients’ view on stopping long-term antidepressant use, a qualitative study,” ACTA CLINICA BELGICA, vol. 77, no. 6, pp. 962–969, 2022.
@article{8734370,
  abstract     = {{Background and aim The rise in long-term antidepressant use is concerning. Long-term antidepressant (AD) use, much longer than recommended by guidelines, can result in risk of adverse events and generate unnecessary costs. In order to mitigate these risks, patients views about their antidepressants and how to discontinue need to be taken into account. We aimed to explore patients' experiences and views of discontinuing long-term AD, barriers and facilitators of discontinuation and required support. Methods Semi-structured face to face interviews were conducted with 14 patients with long-term AD use in primary care. Interviews were analysed thematically. Results Participants describe various perceptions about discontinuation. There is fear of returning to their depression, even in those who were ambivalent about the effectiveness and safety of AD continuation. Participants describe low confidence in their own coping resources, fear of stress, and previous negative experiences with stopping. This enhances their perception of AD dependence. Participants indicate the importance of the support of their GP and their social network to help them withdraw. Conclusion Discontinuation of long-term antidepressants is a complex issue for patients. More awareness of the lack of evidence and the potential risks of long-term AD continuation is required. By raising the issue and offering support during discontinuation GPs can help their patients stop AD. A greater focus on non-pharmacological approaches of depression in primary care is needed to reduce unnecessary AD use.}},
  author       = {{Van Leeuwen, Ellen and Anthierens, Sibyl and van Driel, Mieke and De Sutter, An and De Beir, Rani and Christiaens, Thierry}},
  issn         = {{1784-3286}},
  journal      = {{ACTA CLINICA BELGICA}},
  keywords     = {{General Medicine,Antidepressant discontinuation,depression,general practice,long-term antidepressant use,qualitative research,PERSPECTIVES,HEALTH}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{962--969}},
  title        = {{Should I, can I, dare I? Patients’ view on stopping long-term antidepressant use, a qualitative study}},
  url          = {{http://doi.org/10.1080/17843286.2021.2024384}},
  volume       = {{77}},
  year         = {{2022}},
}

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