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Dyslipidemia management in patients with coronary artery disease : data from the POLASPIRE survey

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Abstract
Lipid-lowering in patients with coronary artery disease (CAD) is related to a lower risk of cardiovascular events. We evaluated factors related to the management of hypercholesterolemia in patients with established CAD. Patients were interviewed 6-18 months after hospitalization for an acute coronary syndrome (ACS) or a myocardial revascularization procedure. Statins were prescribed at discharge to 94.4% of patients, while 68.1% of the patients hospitalized for an ACS were prescribed a high-dose statin. Hospitalization in a teaching hospital, percutaneous coronary intervention, cholesterol measurement during hospitalization and the male sex were related to prescription of statins at discharge. The intensity of lipid-lowering therapy in the post-discharge period increased in 17.3%, decreased in 11.7%, and did not change in 71.0% of the patients. The prescription of a lipid-lowering drug (LLD) at discharge (odds ratio 5.88 [95% confidence intervals 3.05-11.34]) and a consultation with a cardiologist (2.48 [1.51-4.08]) were related to the use of LLDs, while age (1.32 [1.10-1.59] per 10 years), loneliness (0.42 [0.19-0.94]), professional activity (1.56 [1.13-2.16]), and diabetes (1.66 [1.27-2.16]) were related to achieving an LDL cholesterol goal 6-18 months after discharge. In conclusion, health-system-related factors are associated with the LLD utilization, whereas mainly patient-related factors are related to the control of hypercholesterolemia following hospitalization for CAD.
Keywords
General Medicine, cholesterol, coronary artery disease, hypercholesterolemia, secondary prevention, ISCHEMIC-HEART-DISEASE, SECONDARY PREVENTION, CARDIOVASCULAR RISK, CRACOVIAN PROGRAM, LIFE-STYLE, HOSPITALIZATION, PHYSICIANS, COUNTRIES, THERAPY, SOCIETY

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MLA
Jankowski, Piotr, et al. “Dyslipidemia Management in Patients with Coronary Artery Disease : Data from the POLASPIRE Survey.” JOURNAL OF CLINICAL MEDICINE, vol. 10, no. 16, 2021, doi:10.3390/jcm10163711.
APA
Jankowski, P., Kozieł, P., Setny, M., Paniczko, M., Haberka, M., Banach, M., … Pająk, A. (2021). Dyslipidemia management in patients with coronary artery disease : data from the POLASPIRE survey. JOURNAL OF CLINICAL MEDICINE, 10(16). https://doi.org/10.3390/jcm10163711
Chicago author-date
Jankowski, Piotr, Paweł Kozieł, Małgorzata Setny, Marlena Paniczko, Maciej Haberka, Maciej Banach, Dirk De Bacquer, et al. 2021. “Dyslipidemia Management in Patients with Coronary Artery Disease : Data from the POLASPIRE Survey.” JOURNAL OF CLINICAL MEDICINE 10 (16). https://doi.org/10.3390/jcm10163711.
Chicago author-date (all authors)
Jankowski, Piotr, Paweł Kozieł, Małgorzata Setny, Marlena Paniczko, Maciej Haberka, Maciej Banach, Dirk De Bacquer, Gui De Backer, Kornelia Kotseva, David Wood, Zbigniew Gąsior, Karol Kamiński, Dariusz Kosior, and Andrzej Pająk. 2021. “Dyslipidemia Management in Patients with Coronary Artery Disease : Data from the POLASPIRE Survey.” JOURNAL OF CLINICAL MEDICINE 10 (16). doi:10.3390/jcm10163711.
Vancouver
1.
Jankowski P, Kozieł P, Setny M, Paniczko M, Haberka M, Banach M, et al. Dyslipidemia management in patients with coronary artery disease : data from the POLASPIRE survey. JOURNAL OF CLINICAL MEDICINE. 2021;10(16).
IEEE
[1]
P. Jankowski et al., “Dyslipidemia management in patients with coronary artery disease : data from the POLASPIRE survey,” JOURNAL OF CLINICAL MEDICINE, vol. 10, no. 16, 2021.
@article{8732386,
  abstract     = {{Lipid-lowering in patients with coronary artery disease (CAD) is related to a lower risk of cardiovascular events. We evaluated factors related to the management of hypercholesterolemia in patients with established CAD. Patients were interviewed 6-18 months after hospitalization for an acute coronary syndrome (ACS) or a myocardial revascularization procedure. Statins were prescribed at discharge to 94.4% of patients, while 68.1% of the patients hospitalized for an ACS were prescribed a high-dose statin. Hospitalization in a teaching hospital, percutaneous coronary intervention, cholesterol measurement during hospitalization and the male sex were related to prescription of statins at discharge. The intensity of lipid-lowering therapy in the post-discharge period increased in 17.3%, decreased in 11.7%, and did not change in 71.0% of the patients. The prescription of a lipid-lowering drug (LLD) at discharge (odds ratio 5.88 [95% confidence intervals 3.05-11.34]) and a consultation with a cardiologist (2.48 [1.51-4.08]) were related to the use of LLDs, while age (1.32 [1.10-1.59] per 10 years), loneliness (0.42 [0.19-0.94]), professional activity (1.56 [1.13-2.16]), and diabetes (1.66 [1.27-2.16]) were related to achieving an LDL cholesterol goal 6-18 months after discharge. In conclusion, health-system-related factors are associated with the LLD utilization, whereas mainly patient-related factors are related to the control of hypercholesterolemia following hospitalization for CAD.}},
  articleno    = {{3711}},
  author       = {{Jankowski, Piotr and Kozieł, Paweł and Setny, Małgorzata and Paniczko, Marlena and Haberka, Maciej and Banach, Maciej and De Bacquer, Dirk and De Backer, Gui and Kotseva, Kornelia and Wood, David and Gąsior, Zbigniew and Kamiński, Karol and Kosior, Dariusz and Pająk, Andrzej}},
  issn         = {{2077-0383}},
  journal      = {{JOURNAL OF CLINICAL MEDICINE}},
  keywords     = {{General Medicine,cholesterol,coronary artery disease,hypercholesterolemia,secondary prevention,ISCHEMIC-HEART-DISEASE,SECONDARY PREVENTION,CARDIOVASCULAR RISK,CRACOVIAN PROGRAM,LIFE-STYLE,HOSPITALIZATION,PHYSICIANS,COUNTRIES,THERAPY,SOCIETY}},
  language     = {{eng}},
  number       = {{16}},
  pages        = {{11}},
  title        = {{Dyslipidemia management in patients with coronary artery disease : data from the POLASPIRE survey}},
  url          = {{http://doi.org/10.3390/jcm10163711}},
  volume       = {{10}},
  year         = {{2021}},
}

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