Academic Bibliography

 Search 200 years of publications by Ghent University researchers.
Advanced search
1 file | 1.96 MB
Add to list
  1. Search results
  2. Autonomic symptoms and associated fac...

Autonomic symptoms and associated factors in patients with chronic heart failure

Hellen Da Silva Van den Bosch (UGent) , Sofie Pardaens, Marc Vanderheyden, Johan De Sutter (UGent) , Heleen Demeyer (UGent) , Michel De Pauw (UGent) , Laurent Demulier (UGent) , Jan Stautemas (UGent) and Patrick Calders (UGent)
(2023) ACTA CARDIOLOGICA. 78(2). p.203-211
Author
Organization
Abstract
Objective Autonomic disorders are common in chronic illness, and their symptoms may restrict the daily functioning of patients. However, in chronic heart failure, extensive knowledge about autonomic symptoms is still lacking. This study aims to explore self-perceived autonomic symptoms, associated factors, and their relationship with health-related quality of life in chronic heart failure. Methods One hundred and twenty-four patients with documented chronic heart failure (men and women; 50-86 years) and 124 sex and age-matched controls participated in this study. The participants filled validated questionnaires about autonomic symptom profile (COMPASS 31), fatigue (CIS, Checklist for individual strength), anxiety and depression (HADS, Hospital Anxiety and Depression), and health-related quality of life (SF36). Non-parametric statistics were performed to analyse the data. Results Total score for autonomic symptoms was higher in chronic heart failure compared to controls [Median: 14.9; IQR: 6.2-25.1 vs. 7.3; 0-18; p < 0.001], especially for orthostatic hypotension [Median: 8; IQR: 0-16 vs. 0; 0-12; p < 0.001], vasomotor [Median: 0; IQR: 0-0 vs. 0; 0-0; p < 0.001] and secretomotor function [Median: 0; IQR: 0-4.2 vs. 0; 0-2.1; p = 0.013]. High scores for autonomic symptoms were moderate correlated with higher scores of fatigue, anxiety and depression (0.343 <= rs >= 0.420; p < 0.001) and with decreased health-related quality of life (-0.454; p < 0.01). Conclusion Autonomic symptoms, especially for orthostatic intolerance, vasomotor and secretomotor subdomains, are prevalent and are associated with fatigue complaints and poor health-related quality of life in CHF.
Keywords
Cardiology and Cardiovascular Medicine, General Medicine, Autonomic symptoms, chronic heart failure, associated factors, health-related quality of life, ORTHOSTATIC HYPOTENSION, COMPASS 31, ANXIETY, DEPRESSION, NEUROPATHY, DIAGNOSIS, FATIGUE, BURDEN

Downloads

  • Download
    dasilva AAM.pdf
    • full text (Accepted manuscript)
    • |
    • open access
    • |
    • PDF
    • |
    • 1.96 MB

Citation

Please use this url to cite or link to this publication:

MLA
Da Silva Van den Bosch, Hellen, et al. “Autonomic Symptoms and Associated Factors in Patients with Chronic Heart Failure.” ACTA CARDIOLOGICA, vol. 78, no. 2, 2023, pp. 203–11, doi:10.1080/00015385.2021.2010953.
APA
Da Silva Van den Bosch, H., Pardaens, S., Vanderheyden, M., De Sutter, J., Demeyer, H., De Pauw, M., … Calders, P. (2023). Autonomic symptoms and associated factors in patients with chronic heart failure. ACTA CARDIOLOGICA, 78(2), 203–211. https://doi.org/10.1080/00015385.2021.2010953
Chicago author-date
Da Silva Van den Bosch, Hellen, Sofie Pardaens, Marc Vanderheyden, Johan De Sutter, Heleen Demeyer, Michel De Pauw, Laurent Demulier, Jan Stautemas, and Patrick Calders. 2023. “Autonomic Symptoms and Associated Factors in Patients with Chronic Heart Failure.” ACTA CARDIOLOGICA 78 (2): 203–11. https://doi.org/10.1080/00015385.2021.2010953.
Chicago author-date (all authors)
Da Silva Van den Bosch, Hellen, Sofie Pardaens, Marc Vanderheyden, Johan De Sutter, Heleen Demeyer, Michel De Pauw, Laurent Demulier, Jan Stautemas, and Patrick Calders. 2023. “Autonomic Symptoms and Associated Factors in Patients with Chronic Heart Failure.” ACTA CARDIOLOGICA 78 (2): 203–211. doi:10.1080/00015385.2021.2010953.
Vancouver
1.
Da Silva Van den Bosch H, Pardaens S, Vanderheyden M, De Sutter J, Demeyer H, De Pauw M, et al. Autonomic symptoms and associated factors in patients with chronic heart failure. ACTA CARDIOLOGICA. 2023;78(2):203–11.
IEEE
[1]
H. Da Silva Van den Bosch et al., “Autonomic symptoms and associated factors in patients with chronic heart failure,” ACTA CARDIOLOGICA, vol. 78, no. 2, pp. 203–211, 2023.
@article{8730181,
  abstract     = {{Objective Autonomic disorders are common in chronic illness, and their symptoms may restrict the daily functioning of patients. However, in chronic heart failure, extensive knowledge about autonomic symptoms is still lacking. This study aims to explore self-perceived autonomic symptoms, associated factors, and their relationship with health-related quality of life in chronic heart failure. Methods One hundred and twenty-four patients with documented chronic heart failure (men and women; 50-86 years) and 124 sex and age-matched controls participated in this study. The participants filled validated questionnaires about autonomic symptom profile (COMPASS 31), fatigue (CIS, Checklist for individual strength), anxiety and depression (HADS, Hospital Anxiety and Depression), and health-related quality of life (SF36). Non-parametric statistics were performed to analyse the data. Results Total score for autonomic symptoms was higher in chronic heart failure compared to controls [Median: 14.9; IQR: 6.2-25.1 vs. 7.3; 0-18; p < 0.001], especially for orthostatic hypotension [Median: 8; IQR: 0-16 vs. 0; 0-12; p < 0.001], vasomotor [Median: 0; IQR: 0-0 vs. 0; 0-0; p < 0.001] and secretomotor function [Median: 0; IQR: 0-4.2 vs. 0; 0-2.1; p = 0.013]. High scores for autonomic symptoms were moderate correlated with higher scores of fatigue, anxiety and depression (0.343 <= rs >= 0.420; p < 0.001) and with decreased health-related quality of life (-0.454; p < 0.01). Conclusion Autonomic symptoms, especially for orthostatic intolerance, vasomotor and secretomotor subdomains, are prevalent and are associated with fatigue complaints and poor health-related quality of life in CHF.}},
  author       = {{Da Silva Van den Bosch, Hellen and Pardaens, Sofie and Vanderheyden, Marc and De Sutter, Johan and Demeyer, Heleen and De Pauw, Michel and Demulier, Laurent and Stautemas, Jan and Calders, Patrick}},
  issn         = {{0001-5385}},
  journal      = {{ACTA CARDIOLOGICA}},
  keywords     = {{Cardiology and Cardiovascular Medicine,General Medicine,Autonomic symptoms,chronic heart failure,associated factors,health-related quality of life,ORTHOSTATIC HYPOTENSION,COMPASS 31,ANXIETY,DEPRESSION,NEUROPATHY,DIAGNOSIS,FATIGUE,BURDEN}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{203--211}},
  title        = {{Autonomic symptoms and associated factors in patients with chronic heart failure}},
  url          = {{http://doi.org/10.1080/00015385.2021.2010953}},
  volume       = {{78}},
  year         = {{2023}},
}
Altmetric
View in Altmetric
Web of Science
Times cited: