Sea spray aerosols contain the major component of human lung surfactant
- Author
- Emmanuel Van Acker, Maarten De Rijcke, Zixia Liu (UGent) , Jana Asselman (UGent) , Karel De Schamphelaere (UGent) , Lynn Vanhaecke (UGent) and Colin Janssen (UGent)
- Organization
- Project
- Abstract
- Marine phytoplankton influence the composition of sea spray aerosols (SSAs) by releasing various compounds. The biogenic surfactant dipalmitoylphosphatidylcholine (DPPC) is known to accumulate in the sea surface microlayer, but its aerosolization has never been confirmed. We conducted a 1 year SSA sampling campaign at the Belgian coast and analyzed the SSA composition. We quantified DPPC at a median and maximum air concentration of 7.1 and 33 pg m(-3), respectively. This discovery may be of great importance for the field linking ocean processes to human health as DPPC is the major component of human lung surfactant and is used as excipient in medical aerosol therapy. The natural airborne exposure to DPPC seems too low to induce direct human health effects but may facilitate the effects of other marine bioactive compounds. By analyzing various environmental variables in relation to the DPPC air concentration, using a generalized linear model, we established that wave height is a key environmental predictor and that it has an inverse relationship. We also demonstrated that DPPC content in SSAs is positively correlated with enriched aerosolization of Mg2+ and Ca2+. In conclusion, our findings are not only important from a human health perspective but they also advance our understanding of the production and composition of SSAs.
- Keywords
- sea spray aerosols, sea surface microlayer, dipalmitoylphosphatidylcholine (DPPC), potential human health effects, airborne exposure, UHPLC-HRMS, ORGANIC-MATTER ENRICHMENT, MARINE AEROSOL, PULMONARY SURFACTANT, HUMAN HEALTH, DPPC MONOLAYERS, NORTH-SEA, WATER, MICROLAYER, OCEAN, TEMPERATURE
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-8727112
- MLA
- Van Acker, Emmanuel, et al. “Sea Spray Aerosols Contain the Major Component of Human Lung Surfactant.” ENVIRONMENTAL SCIENCE & TECHNOLOGY, vol. 55, no. 23, 2021, pp. 15989–6000, doi:10.1021/acs.est.1c04075.
- APA
- Van Acker, E., De Rijcke, M., Liu, Z., Asselman, J., De Schamphelaere, K., Vanhaecke, L., & Janssen, C. (2021). Sea spray aerosols contain the major component of human lung surfactant. ENVIRONMENTAL SCIENCE & TECHNOLOGY, 55(23), 15989–16000. https://doi.org/10.1021/acs.est.1c04075
- Chicago author-date
- Van Acker, Emmanuel, Maarten De Rijcke, Zixia Liu, Jana Asselman, Karel De Schamphelaere, Lynn Vanhaecke, and Colin Janssen. 2021. “Sea Spray Aerosols Contain the Major Component of Human Lung Surfactant.” ENVIRONMENTAL SCIENCE & TECHNOLOGY 55 (23): 15989–0. https://doi.org/10.1021/acs.est.1c04075.
- Chicago author-date (all authors)
- Van Acker, Emmanuel, Maarten De Rijcke, Zixia Liu, Jana Asselman, Karel De Schamphelaere, Lynn Vanhaecke, and Colin Janssen. 2021. “Sea Spray Aerosols Contain the Major Component of Human Lung Surfactant.” ENVIRONMENTAL SCIENCE & TECHNOLOGY 55 (23): 15989–16000. doi:10.1021/acs.est.1c04075.
- Vancouver
- 1.Van Acker E, De Rijcke M, Liu Z, Asselman J, De Schamphelaere K, Vanhaecke L, et al. Sea spray aerosols contain the major component of human lung surfactant. ENVIRONMENTAL SCIENCE & TECHNOLOGY. 2021;55(23):15989–6000.
- IEEE
- [1]E. Van Acker et al., “Sea spray aerosols contain the major component of human lung surfactant,” ENVIRONMENTAL SCIENCE & TECHNOLOGY, vol. 55, no. 23, pp. 15989–16000, 2021.
@article{8727112,
abstract = {{Marine phytoplankton influence the composition of sea spray aerosols (SSAs) by releasing various compounds. The biogenic surfactant dipalmitoylphosphatidylcholine (DPPC) is known to accumulate in the sea surface microlayer, but its aerosolization has never been confirmed. We conducted a 1 year SSA sampling campaign at the Belgian coast and analyzed the SSA composition. We quantified DPPC at a median and maximum air concentration of 7.1 and 33 pg m(-3), respectively. This discovery may be of great importance for the field linking ocean processes to human health as DPPC is the major component of human lung surfactant and is used as excipient in medical aerosol therapy. The natural airborne exposure to DPPC seems too low to induce direct human health effects but may facilitate the effects of other marine bioactive compounds. By analyzing various environmental variables in relation to the DPPC air concentration, using a generalized linear model, we established that wave height is a key environmental predictor and that it has an inverse relationship. We also demonstrated that DPPC content in SSAs is positively correlated with enriched aerosolization of Mg2+ and Ca2+. In conclusion, our findings are not only important from a human health perspective but they also advance our understanding of the production and composition of SSAs.}},
author = {{Van Acker, Emmanuel and De Rijcke, Maarten and Liu, Zixia and Asselman, Jana and De Schamphelaere, Karel and Vanhaecke, Lynn and Janssen, Colin}},
issn = {{0013-936X}},
journal = {{ENVIRONMENTAL SCIENCE & TECHNOLOGY}},
keywords = {{sea spray aerosols,sea surface microlayer,dipalmitoylphosphatidylcholine (DPPC),potential human health effects,airborne exposure,UHPLC-HRMS,ORGANIC-MATTER ENRICHMENT,MARINE AEROSOL,PULMONARY SURFACTANT,HUMAN HEALTH,DPPC MONOLAYERS,NORTH-SEA,WATER,MICROLAYER,OCEAN,TEMPERATURE}},
language = {{eng}},
number = {{23}},
pages = {{15989--16000}},
title = {{Sea spray aerosols contain the major component of human lung surfactant}},
url = {{http://doi.org/10.1021/acs.est.1c04075}},
volume = {{55}},
year = {{2021}},
}
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