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Tubular bioartificial organs : from physiological requirements to fabrication processes and resulting properties : a critical review

(2022) CELLS TISSUES ORGANS. 211(4). p.420-446
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Organization
Abstract
In this featured review manuscript, the aim is to present a critical survey on the processes available for fabricating bioartificial organs (BAOs). The focus will be on hollow tubular organs for the transport of anabolites and catabolites, i.e., vessels, trachea, esophagus, ureter and urethra, and intestine. First, the anatomic hierarchical structures of tubular organs, as well as their principal physiological functions, will be presented, as this constitutes the mandatory requirements for effectively designing and developing physiologically relevant BAOs. Second, 3D bioprinting, solution electrospinning, and melt electrowriting will be introduced, together with their capacity to match the requirements imposed by designing scaffolds compatible with the anatomical and physiologically relevant environment. Finally, the intrinsic correlation between processes, materials, and cells will be critically discussed, and directives defining the strengths, weaknesses, and opportunities offered by each process will be proposed for assisting bioengineers in the selection of the appropriate process for the target BAO and its specific required functions.
Keywords
Histology, Anatomy, Regenerative medicine, Tubular organs, 3D bioprinting, Solution electrospinning, Melt electrowriting, TISSUE-ENGINEERED TRACHEA, MECHANICAL-PROPERTIES, EXTRACELLULAR-MATRIX, VASCULAR GRAFT, BIOMECHANICAL PROPERTIES, REGENERATIVE MEDICINE, DRUG-DELIVERY, BLOOD-VESSELS, STEM-CELLS, SCAFFOLDS

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MLA
Pien, Nele, et al. “Tubular Bioartificial Organs : From Physiological Requirements to Fabrication Processes and Resulting Properties : A Critical Review.” CELLS TISSUES ORGANS, vol. 211, no. 4, 2022, pp. 420–46, doi:10.1159/000519207.
APA
Pien, N., Palladino, S., Copes, F., Candiani, G., Dubruel, P., Van Vlierberghe, S., & Mantovani, D. (2022). Tubular bioartificial organs : from physiological requirements to fabrication processes and resulting properties : a critical review. CELLS TISSUES ORGANS, 211(4), 420–446. https://doi.org/10.1159/000519207
Chicago author-date
Pien, Nele, Sara Palladino, Francesco Copes, Gabriele Candiani, Peter Dubruel, Sandra Van Vlierberghe, and Diego Mantovani. 2022. “Tubular Bioartificial Organs : From Physiological Requirements to Fabrication Processes and Resulting Properties : A Critical Review.” CELLS TISSUES ORGANS 211 (4): 420–46. https://doi.org/10.1159/000519207.
Chicago author-date (all authors)
Pien, Nele, Sara Palladino, Francesco Copes, Gabriele Candiani, Peter Dubruel, Sandra Van Vlierberghe, and Diego Mantovani. 2022. “Tubular Bioartificial Organs : From Physiological Requirements to Fabrication Processes and Resulting Properties : A Critical Review.” CELLS TISSUES ORGANS 211 (4): 420–446. doi:10.1159/000519207.
Vancouver
1.
Pien N, Palladino S, Copes F, Candiani G, Dubruel P, Van Vlierberghe S, et al. Tubular bioartificial organs : from physiological requirements to fabrication processes and resulting properties : a critical review. CELLS TISSUES ORGANS. 2022;211(4):420–46.
IEEE
[1]
N. Pien et al., “Tubular bioartificial organs : from physiological requirements to fabrication processes and resulting properties : a critical review,” CELLS TISSUES ORGANS, vol. 211, no. 4, pp. 420–446, 2022.
@article{8721418,
  abstract     = {{In this featured review manuscript, the aim is to present a critical survey on the processes available for fabricating bioartificial organs (BAOs). The focus will be on hollow tubular organs for the transport of anabolites and catabolites, i.e., vessels, trachea, esophagus, ureter and urethra, and intestine. First, the anatomic hierarchical structures of tubular organs, as well as their principal physiological functions, will be presented, as this constitutes the mandatory requirements for effectively designing and developing physiologically relevant BAOs. Second, 3D bioprinting, solution electrospinning, and melt electrowriting will be introduced, together with their capacity to match the requirements imposed by designing scaffolds compatible with the anatomical and physiologically relevant environment. Finally, the intrinsic correlation between processes, materials, and cells will be critically discussed, and directives defining the strengths, weaknesses, and opportunities offered by each process will be proposed for assisting bioengineers in the selection of the appropriate process for the target BAO and its specific required functions.}},
  author       = {{Pien, Nele and Palladino, Sara and Copes, Francesco and Candiani, Gabriele and Dubruel, Peter and Van Vlierberghe, Sandra and Mantovani, Diego}},
  issn         = {{1422-6405}},
  journal      = {{CELLS TISSUES ORGANS}},
  keywords     = {{Histology,Anatomy,Regenerative medicine,Tubular organs,3D bioprinting,Solution electrospinning,Melt electrowriting,TISSUE-ENGINEERED TRACHEA,MECHANICAL-PROPERTIES,EXTRACELLULAR-MATRIX,VASCULAR GRAFT,BIOMECHANICAL PROPERTIES,REGENERATIVE MEDICINE,DRUG-DELIVERY,BLOOD-VESSELS,STEM-CELLS,SCAFFOLDS}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{420--446}},
  title        = {{Tubular bioartificial organs : from physiological requirements to fabrication processes and resulting properties : a critical review}},
  url          = {{http://doi.org/10.1159/000519207}},
  volume       = {{211}},
  year         = {{2022}},
}

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