What can biofabrication do for space and what can space do for biofabrication?
- Author
- Lorenzo Moroni, Kevin Tabury, Hilde Stenuit, Daniela Grimm, Sarah Baatout (UGent) and Vladimir Mironov
- Organization
- Abstract
- Biofabrication in space is one of the novel promising and prospective research directions in the rapidly emerging field of space STEM. There are several advantages of biofabrication in space. Under microgravity, it is possible to engineer constructs using more fluidic channels and thus more biocompatible bioinks. Microgravity enables biofabrication of tissue and organ constructs of more complex geometries, thus facilitating novel scaffold-, label-, and nozzle-free technologies based on multi-levitation principles. However, when exposed to microgravity and cosmic radiation, biofabricated tissues could be used to study pathophysiological phenomena that will be useful on Earth and for deep space manned missions. Here, we provide leading concepts about the potential mutual benefits of the application of biofabrication technologies in space.
- Keywords
- Bioengineering, Biotechnology, organoids, spheroids, weightlessness, microgravity (μg), cosmic radiation, magnetic levitation, self-assembly microfluidics, MICROGRAVITY, ORGANOIDS, RADIATION, SKILLS, CHALLENGES, TISSUES
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-8720731
- MLA
- Moroni, Lorenzo, et al. “What Can Biofabrication Do for Space and What Can Space Do for Biofabrication?” TRENDS IN BIOTECHNOLOGY, vol. 40, no. 4, 2022, pp. 398–411, doi:10.1016/j.tibtech.2021.08.008.
- APA
- Moroni, L., Tabury, K., Stenuit, H., Grimm, D., Baatout, S., & Mironov, V. (2022). What can biofabrication do for space and what can space do for biofabrication? TRENDS IN BIOTECHNOLOGY, 40(4), 398–411. https://doi.org/10.1016/j.tibtech.2021.08.008
- Chicago author-date
- Moroni, Lorenzo, Kevin Tabury, Hilde Stenuit, Daniela Grimm, Sarah Baatout, and Vladimir Mironov. 2022. “What Can Biofabrication Do for Space and What Can Space Do for Biofabrication?” TRENDS IN BIOTECHNOLOGY 40 (4): 398–411. https://doi.org/10.1016/j.tibtech.2021.08.008.
- Chicago author-date (all authors)
- Moroni, Lorenzo, Kevin Tabury, Hilde Stenuit, Daniela Grimm, Sarah Baatout, and Vladimir Mironov. 2022. “What Can Biofabrication Do for Space and What Can Space Do for Biofabrication?” TRENDS IN BIOTECHNOLOGY 40 (4): 398–411. doi:10.1016/j.tibtech.2021.08.008.
- Vancouver
- 1.Moroni L, Tabury K, Stenuit H, Grimm D, Baatout S, Mironov V. What can biofabrication do for space and what can space do for biofabrication? TRENDS IN BIOTECHNOLOGY. 2022;40(4):398–411.
- IEEE
- [1]L. Moroni, K. Tabury, H. Stenuit, D. Grimm, S. Baatout, and V. Mironov, “What can biofabrication do for space and what can space do for biofabrication?,” TRENDS IN BIOTECHNOLOGY, vol. 40, no. 4, pp. 398–411, 2022.
@article{8720731,
abstract = {{Biofabrication in space is one of the novel promising and prospective research directions in the rapidly emerging field of space STEM. There are several advantages of biofabrication in space. Under microgravity, it is possible to engineer constructs using more fluidic channels and thus more biocompatible bioinks. Microgravity enables biofabrication of tissue and organ constructs of more complex geometries, thus facilitating novel scaffold-, label-, and nozzle-free technologies based on multi-levitation principles. However, when exposed to microgravity and cosmic radiation, biofabricated tissues could be used to study pathophysiological phenomena that will be useful on Earth and for deep space manned missions. Here, we provide leading concepts about the potential mutual benefits of the application of biofabrication technologies in space.}},
author = {{Moroni, Lorenzo and Tabury, Kevin and Stenuit, Hilde and Grimm, Daniela and Baatout, Sarah and Mironov, Vladimir}},
issn = {{0167-7799}},
journal = {{TRENDS IN BIOTECHNOLOGY}},
keywords = {{Bioengineering,Biotechnology,organoids,spheroids,weightlessness,microgravity (μg),cosmic radiation,magnetic levitation,self-assembly microfluidics,MICROGRAVITY,ORGANOIDS,RADIATION,SKILLS,CHALLENGES,TISSUES}},
language = {{eng}},
number = {{4}},
pages = {{398--411}},
title = {{What can biofabrication do for space and what can space do for biofabrication?}},
url = {{http://doi.org/10.1016/j.tibtech.2021.08.008}},
volume = {{40}},
year = {{2022}},
}
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