@article{8703498,
  abstract     = {{The COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) project is a large international collaborative effort to analyze individual-level phenotype data from twins in multiple cohorts from different environments. The main objective is to study factors that modify genetic and environmental variation of height, body mass index (BMI, kg/m(2)) and size at birth, and additionally to address other research questions such as long-term consequences of birth size. The project started in 2013 and is open to all twin projects in the world having height and weight measures on twins with information on zygosity. Thus far, 54 twin projects from 24 countries have provided individual-level data. The CODATwins database includes 489,981 twin individuals (228,635 complete twin pairs). Since many twin cohorts have collected longitudinal data, there is a total of 1,049,785 height and weight observations. For many cohorts, we also have information on birth weight and length, own smoking behavior and own or parental education. We found that the heritability estimates of height and BMI systematically changed from infancy to old age. Remarkably, only minor differences in the heritability estimates were found across cultural-geographic regions, measurement time and birth cohort for height and BMI. In addition to genetic epidemiological studies, we looked at associations of height and BMI with education, birth weight and smoking status. Within-family analyses examined differences within same-sex and opposite-sex dizygotic twins in birth size and later development. The CODATwins project demonstrates the feasibility and value of international collaboration to address gene-by-exposure interactions that require large sample sizes and address the effects of different exposures across time, geographical regions and socioeconomic status.}},
  articleno    = {{PII S1832427419000355}},
  author       = {{Silventoinen, K. and Jelenkovic, A. and Yokoyama, Y. and Sund, R. and Sugawara, M. and Tanaka, M. and Matsumoto, S. and Bogl, L. H. and Freitas, D. L. and Maia, J. A. and Hjelmborg, J. v. B. and Aaltonen, S. and Piirtola, M. and Latvala, A. and Calais-Ferreira, L. and Oliveira, V. C. and Ferreira, P. H. and Ji, F. and Ning, F. and Pang, Z. and Ordoñana, J. R. and Sánchez-Romera, J. F. and Colodro-Conde, L. and Burt, S. A. and Klump, K. L. and Martin, N. G. and Medland, S. E. and Montgomery, G. W. and Kandler, C. and McAdams, T. A. and Eley, T. C. and Gregory, A. M. and Saudino, K. J. and Dubois, L. and Boivin, M. and Brendgen, M. and Dionne, G. and Vitaro, F. and Tarnoki, A. D. and Tarnoki, D. L. and Haworth, C. M. A. and Plomin, R. and Öncel, S. Y. and Aliev, F. and Medda, E. and Nisticò, L. and Toccaceli, V. and Craig, J. M. and Saffery, R. and Siribaddana, S. H. and Hotopf, M. and Sumathipala, A. and Rijsdijk, F. and Jeong, H.-U. and Spector, T. and Mangino, M. and Lachance, G. and Gatz, M. and Butler, D. A. and Gao, W. and Yu, C. and Li, L. and Bayasgalan, G. and Narandalai, D. and Harden, K. P. and Tucker-Drob, E. M. and Christensen, K. and Skytthe, A. and Kyvik, K. O. and Derom, Catherine and Vlietinck, R. F. and Loos, R. J. F. and Cozen, W. and Hwang, A. E. and Mack, T. M. and He, M. and Ding, X. and Silberg, J. L. and Maes, H. H. and Cutler, T. L. and Hopper, J. L. and Magnusson, P. K. E. and Pedersen, N. L. and Dahl Aslan, A. K. and Baker, L. A. and Tuvblad, C. and Bjerregaard-Andersen, M. and Beck-Nielsen, H. and Sodemann, M. and Ullemar, V. and Almqvist, C. and Tan, Q. and Zhang, D. and Swan, G. E. and Krasnow, R. and Jang, K. L. and Knafo-Noam, A. and Mankuta, D. and Abramson, L. and Lichtenstein, P. and Krueger, R. F. and McGue, M. and Pahlen, S. and Tynelius, P. and Rasmussen, F. and Duncan, G. E. and Buchwald, D. and Corley, R. P. and Huibregtse, B. M. and Nelson, T. L. and Whitfield, K. E. and Franz, C. E. and Kremen, W. S. and Lyons, M. J. and Ooki, S. and Brandt, I. and Nilsen, T. S. and Harris, J. R. and Sung, J. and Park, H. A. and Lee, J. and Lee, S. J. and Willemsen, G. and Bartels, M. and van Beijsterveldt, C. E. M. and Llewellyn, C. H. and Fisher, A. and Rebato, E. and Busjahn, A. and Tomizawa, R. and Inui, F. and Watanabe, M. and Honda, C. and Sakai, N. and Hur, Y.-M. and Sørensen, T. I. A. and Boomsma, D. I. and Kaprio, J.}},
  issn         = {{1832-4274}},
  journal      = {{TWIN RESEARCH AND HUMAN GENETICS}},
  keywords     = {{Obstetrics and Gynaecology,Genetics(clinical),Pediatrics,Perinatology,and Child Health,Twins,international comparisons,heritability,height,BMI,birth size,education,BODY-MASS INDEX,POOLED ANALYSIS,ENVIRONMENTAL VARIATION,BIRTH COHORTS,OLD-AGE,HEIGHT,HERITABILITY,INFANCY,METAANALYSIS,ADULTHOOD}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{PII S1832427419000355:800--PII S1832427419000355:808}},
  title        = {{The CODATwins Project : the current status and recent findings of collaborative project of development of anthropometrical measures in twins}},
  url          = {{http://doi.org/10.1017/thg.2019.35}},
  volume       = {{22}},
  year         = {{2019}},
}

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