Assessment of structural lesions, synovitis and bone marrow lesions in erosive hand osteoarthritis on MRI (0.3T) compared to the radiographic anatomical Verbruggen-Veys score
- Author
- Edem Allado, Ruth Wittoek (UGent) , Stephanie Ferrero, Eliane Albuisson, Isabelle Chary-Valckenaere, Christian Roux and Damien Loeuille
- Organization
- Abstract
- Objective To evaluate prevalence of structural lesions, synovitis and bone marrow lesions (BMLs) on MRI performed with a 0.3T imaging system in patients with erosive hand osteoarthritis (EHOA) and to compare them to the anatomic radiographic Verbruggen-Veys score (VV). Design For this Cross-sectional study, fifty-five EHOA patients were studied with 0.3T contrast-enhanced MRI and radiography (RX) of their dominant hand. Structural lesions were scored according to the OMERACT Hand Osteoarthritis MRI Scoring System as follows: osteophytes and erosions were graded from 0 to 3. On joint destruction lesion synovitis and BMLs were graded from 0 to 1. And on MRI, we evaluated the presence of several structural features: N: normal, O: osteophytic lesions, E: erosive lesions, E/O: osteophytic and erosive lesions and D: joint destruction. RX was scored according to the VV system. Relations between MRI features and VV stages were analysed. Results MRI identified more structural lesions than RX (77.3% versus 74.8%) and particularly more erosive lesions (E or E/O) than VV Phase E (33.5% versus 20.2%). E/O and D were mostly found on MRI. Synovitis and BMLs were significantly associated with E/O and D with the following odds ratios (ORs): 8.4 (95% CI 1.8-13.6); OR: 13.7 (95% CI 2.9-21.0); OR: 15.7 (95% CI 3.2-23.5); OR: 38.5 (95% CI 9.5-57.0), respectively. Conclusion MRI 0.3T appears completely relevant for EHOA lesion analysis. First, MRI shows more erosive lesions than RX in EHOA; second, it allows for the analysis of synovitis and BMLs to be associated with more specific structural MRI features (E/O and D).
- Keywords
- RADIOLOGICAL ASSESSMENT, RELIABILITY, ARTHRITIS, FEATURES, RECOMMENDATIONS, ASSOCIATIONS, SENSITIVITY, PROGRESSION, MANAGEMENT
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Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-8703488
- MLA
- Allado, Edem, et al. “Assessment of Structural Lesions, Synovitis and Bone Marrow Lesions in Erosive Hand Osteoarthritis on MRI (0.3T) Compared to the Radiographic Anatomical Verbruggen-Veys Score.” PLOS ONE, vol. 15, no. 6, 2020, doi:10.1371/journal.pone.0234972.
- APA
- Allado, E., Wittoek, R., Ferrero, S., Albuisson, E., Chary-Valckenaere, I., Roux, C., & Loeuille, D. (2020). Assessment of structural lesions, synovitis and bone marrow lesions in erosive hand osteoarthritis on MRI (0.3T) compared to the radiographic anatomical Verbruggen-Veys score. PLOS ONE, 15(6). https://doi.org/10.1371/journal.pone.0234972
- Chicago author-date
- Allado, Edem, Ruth Wittoek, Stephanie Ferrero, Eliane Albuisson, Isabelle Chary-Valckenaere, Christian Roux, and Damien Loeuille. 2020. “Assessment of Structural Lesions, Synovitis and Bone Marrow Lesions in Erosive Hand Osteoarthritis on MRI (0.3T) Compared to the Radiographic Anatomical Verbruggen-Veys Score.” PLOS ONE 15 (6). https://doi.org/10.1371/journal.pone.0234972.
- Chicago author-date (all authors)
- Allado, Edem, Ruth Wittoek, Stephanie Ferrero, Eliane Albuisson, Isabelle Chary-Valckenaere, Christian Roux, and Damien Loeuille. 2020. “Assessment of Structural Lesions, Synovitis and Bone Marrow Lesions in Erosive Hand Osteoarthritis on MRI (0.3T) Compared to the Radiographic Anatomical Verbruggen-Veys Score.” PLOS ONE 15 (6). doi:10.1371/journal.pone.0234972.
- Vancouver
- 1.Allado E, Wittoek R, Ferrero S, Albuisson E, Chary-Valckenaere I, Roux C, et al. Assessment of structural lesions, synovitis and bone marrow lesions in erosive hand osteoarthritis on MRI (0.3T) compared to the radiographic anatomical Verbruggen-Veys score. PLOS ONE. 2020;15(6).
- IEEE
- [1]E. Allado et al., “Assessment of structural lesions, synovitis and bone marrow lesions in erosive hand osteoarthritis on MRI (0.3T) compared to the radiographic anatomical Verbruggen-Veys score,” PLOS ONE, vol. 15, no. 6, 2020.
@article{8703488, abstract = {{Objective To evaluate prevalence of structural lesions, synovitis and bone marrow lesions (BMLs) on MRI performed with a 0.3T imaging system in patients with erosive hand osteoarthritis (EHOA) and to compare them to the anatomic radiographic Verbruggen-Veys score (VV). Design For this Cross-sectional study, fifty-five EHOA patients were studied with 0.3T contrast-enhanced MRI and radiography (RX) of their dominant hand. Structural lesions were scored according to the OMERACT Hand Osteoarthritis MRI Scoring System as follows: osteophytes and erosions were graded from 0 to 3. On joint destruction lesion synovitis and BMLs were graded from 0 to 1. And on MRI, we evaluated the presence of several structural features: N: normal, O: osteophytic lesions, E: erosive lesions, E/O: osteophytic and erosive lesions and D: joint destruction. RX was scored according to the VV system. Relations between MRI features and VV stages were analysed. Results MRI identified more structural lesions than RX (77.3% versus 74.8%) and particularly more erosive lesions (E or E/O) than VV Phase E (33.5% versus 20.2%). E/O and D were mostly found on MRI. Synovitis and BMLs were significantly associated with E/O and D with the following odds ratios (ORs): 8.4 (95% CI 1.8-13.6); OR: 13.7 (95% CI 2.9-21.0); OR: 15.7 (95% CI 3.2-23.5); OR: 38.5 (95% CI 9.5-57.0), respectively. Conclusion MRI 0.3T appears completely relevant for EHOA lesion analysis. First, MRI shows more erosive lesions than RX in EHOA; second, it allows for the analysis of synovitis and BMLs to be associated with more specific structural MRI features (E/O and D).}}, articleno = {{e0234972}}, author = {{Allado, Edem and Wittoek, Ruth and Ferrero, Stephanie and Albuisson, Eliane and Chary-Valckenaere, Isabelle and Roux, Christian and Loeuille, Damien}}, issn = {{1932-6203}}, journal = {{PLOS ONE}}, keywords = {{RADIOLOGICAL ASSESSMENT,RELIABILITY,ARTHRITIS,FEATURES,RECOMMENDATIONS,ASSOCIATIONS,SENSITIVITY,PROGRESSION,MANAGEMENT}}, language = {{eng}}, number = {{6}}, pages = {{13}}, title = {{Assessment of structural lesions, synovitis and bone marrow lesions in erosive hand osteoarthritis on MRI (0.3T) compared to the radiographic anatomical Verbruggen-Veys score}}, url = {{http://doi.org/10.1371/journal.pone.0234972}}, volume = {{15}}, year = {{2020}}, }
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