
The role of the cerebellum in social and non-social action sequences : a preliminary LF-rTMS study
- Author
- Elien Heleven, Kim van Dun, Sara De Witte (UGent) , Chris Baeken (UGent) and Frank Van Overwalle
- Organization
- Abstract
- An increasing number of studies demonstrated the involvement of the cerebellum in (social) sequence processing. The current preliminary study is the first to investigate the causal involvement of the cerebellum in sequence generation, using low-frequency repetitive transcranial magnetic stimulation (LF-rTMS). By targeting the posterior cerebellum, we hypothesized that the induced neuro-excitability modulation would lead to altered performance on a Picture and Story sequencing task, which involve the generation of the correct chronological order of various social and non-social stories depicted in cartoons or sentences. Our results indicate that participants receiving LF-rTMS over the cerebellum, as compared to sham participants, showed a stronger learning effect from pre to post stimulation for both tasks and for all types of sequences (i.e. mechanical, social scripts, false belief, true belief). No differences between sequence types were observed. Our results suggest a positive effect of LF-rTMS on sequence generation. We conclude that the cerebellum is causally involved in the generation of sequences of social and nonsocial events. Our discussion focuses on recommendations for future studies.
- Keywords
- Biological Psychiatry, Behavioral Neuroscience, Neuropsychology and Physiological Psychology, Neurology, Psychiatry and Mental health, cerebellum, social action sequences, mentalizing, TMS, Verbal sequencing task, Picture sequencing task, TRANSCRANIAL MAGNETIC STIMULATION, COGNITION, BRAIN, AUTISM, NEUROSTIMULATION, CONNECTIVITY, METAANALYSIS
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-8699373
- MLA
- Heleven, Elien, et al. “The Role of the Cerebellum in Social and Non-Social Action Sequences : A Preliminary LF-RTMS Study.” FRONTIERS IN HUMAN NEUROSCIENCE, vol. 15, 2021, doi:10.3389/fnhum.2021.593821.
- APA
- Heleven, E., van Dun, K., De Witte, S., Baeken, C., & Van Overwalle, F. (2021). The role of the cerebellum in social and non-social action sequences : a preliminary LF-rTMS study. FRONTIERS IN HUMAN NEUROSCIENCE, 15. https://doi.org/10.3389/fnhum.2021.593821
- Chicago author-date
- Heleven, Elien, Kim van Dun, Sara De Witte, Chris Baeken, and Frank Van Overwalle. 2021. “The Role of the Cerebellum in Social and Non-Social Action Sequences : A Preliminary LF-RTMS Study.” FRONTIERS IN HUMAN NEUROSCIENCE 15. https://doi.org/10.3389/fnhum.2021.593821.
- Chicago author-date (all authors)
- Heleven, Elien, Kim van Dun, Sara De Witte, Chris Baeken, and Frank Van Overwalle. 2021. “The Role of the Cerebellum in Social and Non-Social Action Sequences : A Preliminary LF-RTMS Study.” FRONTIERS IN HUMAN NEUROSCIENCE 15. doi:10.3389/fnhum.2021.593821.
- Vancouver
- 1.Heleven E, van Dun K, De Witte S, Baeken C, Van Overwalle F. The role of the cerebellum in social and non-social action sequences : a preliminary LF-rTMS study. FRONTIERS IN HUMAN NEUROSCIENCE. 2021;15.
- IEEE
- [1]E. Heleven, K. van Dun, S. De Witte, C. Baeken, and F. Van Overwalle, “The role of the cerebellum in social and non-social action sequences : a preliminary LF-rTMS study,” FRONTIERS IN HUMAN NEUROSCIENCE, vol. 15, 2021.
@article{8699373, abstract = {{An increasing number of studies demonstrated the involvement of the cerebellum in (social) sequence processing. The current preliminary study is the first to investigate the causal involvement of the cerebellum in sequence generation, using low-frequency repetitive transcranial magnetic stimulation (LF-rTMS). By targeting the posterior cerebellum, we hypothesized that the induced neuro-excitability modulation would lead to altered performance on a Picture and Story sequencing task, which involve the generation of the correct chronological order of various social and non-social stories depicted in cartoons or sentences. Our results indicate that participants receiving LF-rTMS over the cerebellum, as compared to sham participants, showed a stronger learning effect from pre to post stimulation for both tasks and for all types of sequences (i.e. mechanical, social scripts, false belief, true belief). No differences between sequence types were observed. Our results suggest a positive effect of LF-rTMS on sequence generation. We conclude that the cerebellum is causally involved in the generation of sequences of social and nonsocial events. Our discussion focuses on recommendations for future studies.}}, articleno = {{593821}}, author = {{Heleven, Elien and van Dun, Kim and De Witte, Sara and Baeken, Chris and Van Overwalle, Frank}}, issn = {{1662-5161}}, journal = {{FRONTIERS IN HUMAN NEUROSCIENCE}}, keywords = {{Biological Psychiatry,Behavioral Neuroscience,Neuropsychology and Physiological Psychology,Neurology,Psychiatry and Mental health,cerebellum,social action sequences,mentalizing,TMS,Verbal sequencing task,Picture sequencing task,TRANSCRANIAL MAGNETIC STIMULATION,COGNITION,BRAIN,AUTISM,NEUROSTIMULATION,CONNECTIVITY,METAANALYSIS}}, language = {{eng}}, pages = {{7}}, title = {{The role of the cerebellum in social and non-social action sequences : a preliminary LF-rTMS study}}, url = {{http://doi.org/10.3389/fnhum.2021.593821}}, volume = {{15}}, year = {{2021}}, }
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