At the crossroads of survival and death : the reactive oxygen species-ethylene-sugar triad and the unfolded protein response
- Author
- Thomas Depaepe (UGent) , Sophie Hendrix, Henry C. Janse van Rensburg, Wim Van den Ende, Ann Cuypers and Dominique Van Der Straeten (UGent)
- Organization
- Abstract
- Upon stress, a trade-off between plant growth and defense responses defines the capacity for survival. Stress can result in accumulation of misfolded proteins in the endoplasmic reticulum (ER) and other organelles. To cope with these proteotoxic effects, plants rely on the unfolded protein response (UPR). The involvement of reactive oxygen species (ROS), ethylene (ETH), and sugars, as well as their crosstalk, in general stress responses is well established, yet their role in UPR deserves further scrutiny. Here, a synopsis of current evidence for ROS-ETH-sugar crosstalk in UPR is discussed. We propose that this triad acts as a major signaling hub at the crossroads of survival and death, integrating information from ER, chloroplasts, and mitochondria, thereby facilitating a coordinated stress response.
- Keywords
- ENDOPLASMIC-RETICULUM STRESS, TRANSCRIPTION FACTOR, ABIOTIC STRESS, NUCLEAR TRANSLOCATION, ENERGY SENSOR, SNRK1 KINASE, REDOX STATE, CELL-DEATH, ARABIDOPSIS, MITOCHONDRIAL
Downloads
-
published.pdf
- full text (Published version)
- |
- open access
- |
- |
- 2.47 MB
Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-8691934
- MLA
- Depaepe, Thomas, et al. “At the Crossroads of Survival and Death : The Reactive Oxygen Species-Ethylene-Sugar Triad and the Unfolded Protein Response.” TRENDS IN PLANT SCIENCE, vol. 26, no. 4, 2021, pp. 338–51, doi:10.1016/j.tplants.2020.12.007.
- APA
- Depaepe, T., Hendrix, S., Janse van Rensburg, H. C., Van den Ende, W., Cuypers, A., & Van Der Straeten, D. (2021). At the crossroads of survival and death : the reactive oxygen species-ethylene-sugar triad and the unfolded protein response. TRENDS IN PLANT SCIENCE, 26(4), 338–351. https://doi.org/10.1016/j.tplants.2020.12.007
- Chicago author-date
- Depaepe, Thomas, Sophie Hendrix, Henry C. Janse van Rensburg, Wim Van den Ende, Ann Cuypers, and Dominique Van Der Straeten. 2021. “At the Crossroads of Survival and Death : The Reactive Oxygen Species-Ethylene-Sugar Triad and the Unfolded Protein Response.” TRENDS IN PLANT SCIENCE 26 (4): 338–51. https://doi.org/10.1016/j.tplants.2020.12.007.
- Chicago author-date (all authors)
- Depaepe, Thomas, Sophie Hendrix, Henry C. Janse van Rensburg, Wim Van den Ende, Ann Cuypers, and Dominique Van Der Straeten. 2021. “At the Crossroads of Survival and Death : The Reactive Oxygen Species-Ethylene-Sugar Triad and the Unfolded Protein Response.” TRENDS IN PLANT SCIENCE 26 (4): 338–351. doi:10.1016/j.tplants.2020.12.007.
- Vancouver
- 1.Depaepe T, Hendrix S, Janse van Rensburg HC, Van den Ende W, Cuypers A, Van Der Straeten D. At the crossroads of survival and death : the reactive oxygen species-ethylene-sugar triad and the unfolded protein response. TRENDS IN PLANT SCIENCE. 2021;26(4):338–51.
- IEEE
- [1]T. Depaepe, S. Hendrix, H. C. Janse van Rensburg, W. Van den Ende, A. Cuypers, and D. Van Der Straeten, “At the crossroads of survival and death : the reactive oxygen species-ethylene-sugar triad and the unfolded protein response,” TRENDS IN PLANT SCIENCE, vol. 26, no. 4, pp. 338–351, 2021.
@article{8691934,
abstract = {{Upon stress, a trade-off between plant growth and defense responses defines the capacity for survival. Stress can result in accumulation of misfolded proteins in the endoplasmic reticulum (ER) and other organelles. To cope with these proteotoxic effects, plants rely on the unfolded protein response (UPR). The involvement of reactive oxygen species (ROS), ethylene (ETH), and sugars, as well as their crosstalk, in general stress responses is well established, yet their role in UPR deserves further scrutiny. Here, a synopsis of current evidence for ROS-ETH-sugar crosstalk in UPR is discussed. We propose that this triad acts as a major signaling hub at the crossroads of survival and death, integrating information from ER, chloroplasts, and mitochondria, thereby facilitating a coordinated stress response.}},
author = {{Depaepe, Thomas and Hendrix, Sophie and Janse van Rensburg, Henry C. and Van den Ende, Wim and Cuypers, Ann and Van Der Straeten, Dominique}},
issn = {{1360-1385}},
journal = {{TRENDS IN PLANT SCIENCE}},
keywords = {{ENDOPLASMIC-RETICULUM STRESS,TRANSCRIPTION FACTOR,ABIOTIC STRESS,NUCLEAR TRANSLOCATION,ENERGY SENSOR,SNRK1 KINASE,REDOX STATE,CELL-DEATH,ARABIDOPSIS,MITOCHONDRIAL}},
language = {{eng}},
number = {{4}},
pages = {{338--351}},
title = {{At the crossroads of survival and death : the reactive oxygen species-ethylene-sugar triad and the unfolded protein response}},
url = {{http://doi.org/10.1016/j.tplants.2020.12.007}},
volume = {{26}},
year = {{2021}},
}
- Altmetric
- View in Altmetric
- Web of Science
- Times cited: