Altered multi‐segment ankle and foot kinematics during gait in patients with Hypermobile Ehlers‐Danlos Syndrome/Hypermobility spectrum disorder : a case‐control study
- Author
- Stefan Vermeulen (UGent) , Sophie De Mits (UGent) , Roel De Ridder (UGent) , Patrick Calders (UGent) , Joris De Schepper, Fransiska Malfait (UGent) and Lies Rombaut (UGent)
- Organization
- Abstract
- Objective Ankle-foot problems have a considerable impact on daily functioning in patients with hypermobile Ehlers-Danlos syndrome and hypermobility spectrum disorder (hEDS/HSD). Therefore, the objective of this study was to identify alterations in multisegment ankle and foot kinematics during gait and to assess foot function and pain in these patients. Methods Twenty-three women with hEDS/HSD and 23 healthy controls participated in this 3-dimensional gait analysis. Multisegment ankle and foot kinematics were collected using the Ghent Foot Model and analyzed with Statistical Parametric Mapping. Foot function and pain were assessed using visual analog scale scores, the Margolis Pain Diagram, and the Foot Function Index. Results Levels of pain and foot dysfunction were significantly higher in subjects with hEDS/HSD (P < 0.001). Kinematic curve analyses provide evidence for a hypermobile first ray, represented by a significantly increased eversion position of the medial forefoot during stance phase (P < 0.001) in subjects with hEDS/HSD compared to controls. In addition, significantly more dorsiflexion was found in the medial and lateral forefoot and the rearfoot (P < 0.001). At the midfoot, an increased plantar flexion (P < 0.001) and at the level of the hallux a decreased dorsiflexion (P = 0.037) and increased inversion (P < 0.001) and abduction (P = 0.016) were found in subjects with hEDS/HSD. Conclusion This study is the first to apply a multisegment foot model during gait in hEDS/HSD, which confirms the characteristic hypermobility throughout the foot, especially the hypermobile first ray.
- Keywords
- Rheumatology, JOINT HYPERMOBILITY, 1ST RAY, PAIN, WOMEN, CLASSIFICATION, INDIVIDUALS, MOBILITY, STRATEGY, MOTION, LIFE
Downloads
-
E-pub ahead of print.pdf
- full text (Accepted manuscript)
- |
- open access
- |
- |
- 11.75 MB
-
(...).pdf
- full text (Published version)
- |
- UGent only
- |
- |
- 388.83 KB
Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-8691893
- MLA
- Vermeulen, Stefan, et al. “Altered Multi‐segment Ankle and Foot Kinematics during Gait in Patients with Hypermobile Ehlers‐Danlos Syndrome/Hypermobility Spectrum Disorder : A Case‐control Study.” ARTHRITIS CARE & RESEARCH, vol. 74, no. 5, 2022, pp. 841–48, doi:10.1002/acr.24526.
- APA
- Vermeulen, S., De Mits, S., De Ridder, R., Calders, P., De Schepper, J., Malfait, F., & Rombaut, L. (2022). Altered multi‐segment ankle and foot kinematics during gait in patients with Hypermobile Ehlers‐Danlos Syndrome/Hypermobility spectrum disorder : a case‐control study. ARTHRITIS CARE & RESEARCH, 74(5), 841–848. https://doi.org/10.1002/acr.24526
- Chicago author-date
- Vermeulen, Stefan, Sophie De Mits, Roel De Ridder, Patrick Calders, Joris De Schepper, Fransiska Malfait, and Lies Rombaut. 2022. “Altered Multi‐segment Ankle and Foot Kinematics during Gait in Patients with Hypermobile Ehlers‐Danlos Syndrome/Hypermobility Spectrum Disorder : A Case‐control Study.” ARTHRITIS CARE & RESEARCH 74 (5): 841–48. https://doi.org/10.1002/acr.24526.
- Chicago author-date (all authors)
- Vermeulen, Stefan, Sophie De Mits, Roel De Ridder, Patrick Calders, Joris De Schepper, Fransiska Malfait, and Lies Rombaut. 2022. “Altered Multi‐segment Ankle and Foot Kinematics during Gait in Patients with Hypermobile Ehlers‐Danlos Syndrome/Hypermobility Spectrum Disorder : A Case‐control Study.” ARTHRITIS CARE & RESEARCH 74 (5): 841–848. doi:10.1002/acr.24526.
- Vancouver
- 1.Vermeulen S, De Mits S, De Ridder R, Calders P, De Schepper J, Malfait F, et al. Altered multi‐segment ankle and foot kinematics during gait in patients with Hypermobile Ehlers‐Danlos Syndrome/Hypermobility spectrum disorder : a case‐control study. ARTHRITIS CARE & RESEARCH. 2022;74(5):841–8.
- IEEE
- [1]S. Vermeulen et al., “Altered multi‐segment ankle and foot kinematics during gait in patients with Hypermobile Ehlers‐Danlos Syndrome/Hypermobility spectrum disorder : a case‐control study,” ARTHRITIS CARE & RESEARCH, vol. 74, no. 5, pp. 841–848, 2022.
@article{8691893, abstract = {{Objective Ankle-foot problems have a considerable impact on daily functioning in patients with hypermobile Ehlers-Danlos syndrome and hypermobility spectrum disorder (hEDS/HSD). Therefore, the objective of this study was to identify alterations in multisegment ankle and foot kinematics during gait and to assess foot function and pain in these patients. Methods Twenty-three women with hEDS/HSD and 23 healthy controls participated in this 3-dimensional gait analysis. Multisegment ankle and foot kinematics were collected using the Ghent Foot Model and analyzed with Statistical Parametric Mapping. Foot function and pain were assessed using visual analog scale scores, the Margolis Pain Diagram, and the Foot Function Index. Results Levels of pain and foot dysfunction were significantly higher in subjects with hEDS/HSD (P < 0.001). Kinematic curve analyses provide evidence for a hypermobile first ray, represented by a significantly increased eversion position of the medial forefoot during stance phase (P < 0.001) in subjects with hEDS/HSD compared to controls. In addition, significantly more dorsiflexion was found in the medial and lateral forefoot and the rearfoot (P < 0.001). At the midfoot, an increased plantar flexion (P < 0.001) and at the level of the hallux a decreased dorsiflexion (P = 0.037) and increased inversion (P < 0.001) and abduction (P = 0.016) were found in subjects with hEDS/HSD. Conclusion This study is the first to apply a multisegment foot model during gait in hEDS/HSD, which confirms the characteristic hypermobility throughout the foot, especially the hypermobile first ray.}}, author = {{Vermeulen, Stefan and De Mits, Sophie and De Ridder, Roel and Calders, Patrick and De Schepper, Joris and Malfait, Fransiska and Rombaut, Lies}}, issn = {{2151-464X}}, journal = {{ARTHRITIS CARE & RESEARCH}}, keywords = {{Rheumatology,JOINT HYPERMOBILITY,1ST RAY,PAIN,WOMEN,CLASSIFICATION,INDIVIDUALS,MOBILITY,STRATEGY,MOTION,LIFE}}, language = {{eng}}, number = {{5}}, pages = {{841--848}}, title = {{Altered multi‐segment ankle and foot kinematics during gait in patients with Hypermobile Ehlers‐Danlos Syndrome/Hypermobility spectrum disorder : a case‐control study}}, url = {{http://doi.org/10.1002/acr.24526}}, volume = {{74}}, year = {{2022}}, }
- Altmetric
- View in Altmetric
- Web of Science
- Times cited: