Advanced search
2 files | 3.21 MB Add to list

Au(I)-catalyzed hydration of 1-Iodoalkynes leading to alpha-Iodoketones

(2020) EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. 2020(43). p.6790-6794
Author
Organization
Abstract
A catalytic protocol for the Au(I)-catalyzed hydration of 1-iodoalkynes is disclosed. The use of Au(I)-NHC catalyst enabled the straightforward synthesis of a variety of alpha-iodomethyl ketones in good to excellent yields. The utility of this simple method is further highlighted by showcasing iodination/hydration and hydration/oxidation sequential protocols leading to the construction of molecular complexity.
Keywords
ONE-POT SYNTHESIS, C-H FUNCTIONALIZATION, METAL-FREE, CATALYZED, HYDRATION, METHYL KETONES, CARBONYL-COMPOUNDS, BENZAMIDINES, HYDROCHLORIDE, 1, 3-DICARBONYL COMPOUNDS, OXIDATIVE CYCLIZATION, TERMINAL, ALKYNES, Gold, N&#8208, heterocyclic carbenes, Iodination, Hydration, Sequential

Downloads

  • (...).pdf
    • full text (Published version)
    • |
    • UGent only
    • |
    • PDF
    • |
    • 789.87 KB
  • (...).pdf
    • supplementary material
    • |
    • UGent only
    • |
    • PDF
    • |
    • 2.42 MB

Citation

Please use this url to cite or link to this publication:

MLA
Gomez-Herrera, Alberto, et al. “Au(I)-Catalyzed Hydration of 1-Iodoalkynes Leading to Alpha-Iodoketones.” EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, vol. 2020, no. 43, 2020, pp. 6790–94, doi:10.1002/ejoc.202001238.
APA
Gomez-Herrera, A., ishfaq, I. H., Porré, M., Nahra, F., & Cazin, C. (2020). Au(I)-catalyzed hydration of 1-Iodoalkynes leading to alpha-Iodoketones. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2020(43), 6790–6794. https://doi.org/10.1002/ejoc.202001238
Chicago author-date
Gomez-Herrera, Alberto, Ibni Hashim ishfaq, Marre Porré, Fady Nahra, and Catherine Cazin. 2020. “Au(I)-Catalyzed Hydration of 1-Iodoalkynes Leading to Alpha-Iodoketones.” EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2020 (43): 6790–94. https://doi.org/10.1002/ejoc.202001238.
Chicago author-date (all authors)
Gomez-Herrera, Alberto, Ibni Hashim ishfaq, Marre Porré, Fady Nahra, and Catherine Cazin. 2020. “Au(I)-Catalyzed Hydration of 1-Iodoalkynes Leading to Alpha-Iodoketones.” EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2020 (43): 6790–6794. doi:10.1002/ejoc.202001238.
Vancouver
1.
Gomez-Herrera A, ishfaq IH, Porré M, Nahra F, Cazin C. Au(I)-catalyzed hydration of 1-Iodoalkynes leading to alpha-Iodoketones. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. 2020;2020(43):6790–4.
IEEE
[1]
A. Gomez-Herrera, I. H. ishfaq, M. Porré, F. Nahra, and C. Cazin, “Au(I)-catalyzed hydration of 1-Iodoalkynes leading to alpha-Iodoketones,” EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, vol. 2020, no. 43, pp. 6790–6794, 2020.
@article{8689551,
  abstract     = {{A catalytic protocol for the Au(I)-catalyzed hydration of 1-iodoalkynes is disclosed. The use of Au(I)-NHC catalyst enabled the straightforward synthesis of a variety of alpha-iodomethyl ketones in good to excellent yields. The utility of this simple method is further highlighted by showcasing iodination/hydration and hydration/oxidation sequential protocols leading to the construction of molecular complexity.}},
  author       = {{Gomez-Herrera, Alberto and ishfaq, Ibni Hashim and Porré, Marre and Nahra, Fady and Cazin, Catherine}},
  issn         = {{1434-193X}},
  journal      = {{EUROPEAN JOURNAL OF ORGANIC CHEMISTRY}},
  keywords     = {{ONE-POT SYNTHESIS,C-H FUNCTIONALIZATION,METAL-FREE,CATALYZED,HYDRATION,METHYL KETONES,CARBONYL-COMPOUNDS,BENZAMIDINES,HYDROCHLORIDE,1,3-DICARBONYL COMPOUNDS,OXIDATIVE CYCLIZATION,TERMINAL,ALKYNES,Gold,N&#8208,heterocyclic carbenes,Iodination,Hydration,Sequential}},
  language     = {{eng}},
  number       = {{43}},
  pages        = {{6790--6794}},
  title        = {{Au(I)-catalyzed hydration of 1-Iodoalkynes leading to alpha-Iodoketones}},
  url          = {{http://dx.doi.org/10.1002/ejoc.202001238}},
  volume       = {{2020}},
  year         = {{2020}},
}

Altmetric
View in Altmetric
Web of Science
Times cited: