Au(I)-catalyzed hydration of 1-Iodoalkynes leading to alpha-Iodoketones
- Author
- Alberto Gomez-Herrera, Ibni Hashim ishfaq (UGent) , Marre Porré, Fady Nahra (UGent) and Catherine Cazin (UGent)
- Organization
- Project
- Abstract
- A catalytic protocol for the Au(I)-catalyzed hydration of 1-iodoalkynes is disclosed. The use of Au(I)-NHC catalyst enabled the straightforward synthesis of a variety of alpha-iodomethyl ketones in good to excellent yields. The utility of this simple method is further highlighted by showcasing iodination/hydration and hydration/oxidation sequential protocols leading to the construction of molecular complexity.
- Keywords
- ONE-POT SYNTHESIS, C-H FUNCTIONALIZATION, METAL-FREE, CATALYZED, HYDRATION, METHYL KETONES, CARBONYL-COMPOUNDS, BENZAMIDINES, HYDROCHLORIDE, 1, 3-DICARBONYL COMPOUNDS, OXIDATIVE CYCLIZATION, TERMINAL, ALKYNES, Gold, N‐, heterocyclic carbenes, Iodination, Hydration, Sequential
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-8689551
- MLA
- Gomez-Herrera, Alberto, et al. “Au(I)-Catalyzed Hydration of 1-Iodoalkynes Leading to Alpha-Iodoketones.” EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, vol. 2020, no. 43, 2020, pp. 6790–94, doi:10.1002/ejoc.202001238.
- APA
- Gomez-Herrera, A., ishfaq, I. H., Porré, M., Nahra, F., & Cazin, C. (2020). Au(I)-catalyzed hydration of 1-Iodoalkynes leading to alpha-Iodoketones. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2020(43), 6790–6794. https://doi.org/10.1002/ejoc.202001238
- Chicago author-date
- Gomez-Herrera, Alberto, Ibni Hashim ishfaq, Marre Porré, Fady Nahra, and Catherine Cazin. 2020. “Au(I)-Catalyzed Hydration of 1-Iodoalkynes Leading to Alpha-Iodoketones.” EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2020 (43): 6790–94. https://doi.org/10.1002/ejoc.202001238.
- Chicago author-date (all authors)
- Gomez-Herrera, Alberto, Ibni Hashim ishfaq, Marre Porré, Fady Nahra, and Catherine Cazin. 2020. “Au(I)-Catalyzed Hydration of 1-Iodoalkynes Leading to Alpha-Iodoketones.” EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2020 (43): 6790–6794. doi:10.1002/ejoc.202001238.
- Vancouver
- 1.Gomez-Herrera A, ishfaq IH, Porré M, Nahra F, Cazin C. Au(I)-catalyzed hydration of 1-Iodoalkynes leading to alpha-Iodoketones. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. 2020;2020(43):6790–4.
- IEEE
- [1]A. Gomez-Herrera, I. H. ishfaq, M. Porré, F. Nahra, and C. Cazin, “Au(I)-catalyzed hydration of 1-Iodoalkynes leading to alpha-Iodoketones,” EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, vol. 2020, no. 43, pp. 6790–6794, 2020.
@article{8689551,
abstract = {{A catalytic protocol for the Au(I)-catalyzed hydration of 1-iodoalkynes is disclosed. The use of Au(I)-NHC catalyst enabled the straightforward synthesis of a variety of alpha-iodomethyl ketones in good to excellent yields. The utility of this simple method is further highlighted by showcasing iodination/hydration and hydration/oxidation sequential protocols leading to the construction of molecular complexity.}},
author = {{Gomez-Herrera, Alberto and ishfaq, Ibni Hashim and Porré, Marre and Nahra, Fady and Cazin, Catherine}},
issn = {{1434-193X}},
journal = {{EUROPEAN JOURNAL OF ORGANIC CHEMISTRY}},
keywords = {{ONE-POT SYNTHESIS,C-H FUNCTIONALIZATION,METAL-FREE,CATALYZED,HYDRATION,METHYL KETONES,CARBONYL-COMPOUNDS,BENZAMIDINES,HYDROCHLORIDE,1,3-DICARBONYL COMPOUNDS,OXIDATIVE CYCLIZATION,TERMINAL,ALKYNES,Gold,N‐,heterocyclic carbenes,Iodination,Hydration,Sequential}},
language = {{eng}},
number = {{43}},
pages = {{6790--6794}},
title = {{Au(I)-catalyzed hydration of 1-Iodoalkynes leading to alpha-Iodoketones}},
url = {{http://doi.org/10.1002/ejoc.202001238}},
volume = {{2020}},
year = {{2020}},
}
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