Advanced search
1 file | 1.71 MB Add to list

Understanding existing and designing novel synthetic routes to Pd-PEPPSI-NHC and Pd-PEPPSI-PR3 pre-catalysts

Sébastien Guillet (UGent) , Vladislav Voloshkin (UGent) , Marina Saab (UGent) , Marek Beliš (UGent) , Kristof Van Hecke (UGent) , Fady Nahra (UGent) and Steven Nolan (UGent)
(2020) CHEMICAL COMMUNICATIONS. 56(44). p.5953-5956
Author
Organization
Abstract
The reaction mechanism leading to the formation of cross-coupling palladium pre-catalysts of the PEPPSI family was investigated. Two intermediates were isolated and proved to be both suitable synthons to the pre-catalysts, with one permitting the design of a novel and greener user-friendly synthetic route. In light of this mechanistic understanding, the traditional one-pot method was shown to be possible using stoichiometric amounts of throw-away ligand, which represents a considerable synthetic improvement over the wasteful "in pyridine" approach.
Keywords
N-HETEROCYCLIC CARBENE, CROSS-COUPLING REACTION, COMPLEXES SYNTHESIS, ARYL HALIDES, AMINATION, PD-PEPPSI-IPENT(CL), PRECATALYST, IPENT

Downloads

  • (...).pdf
    • full text (Published version)
    • |
    • UGent only
    • |
    • PDF
    • |
    • 1.71 MB

Citation

Please use this url to cite or link to this publication:

MLA
Guillet, Sébastien, et al. “Understanding Existing and Designing Novel Synthetic Routes to Pd-PEPPSI-NHC and Pd-PEPPSI-PR3 Pre-Catalysts.” CHEMICAL COMMUNICATIONS, vol. 56, no. 44, Royal Soc Chemistry, 2020, pp. 5953–56, doi:10.1039/d0cc02262d.
APA
Guillet, S., Voloshkin, V., Saab, M., Beliš, M., Van Hecke, K., Nahra, F., & Nolan, S. (2020). Understanding existing and designing novel synthetic routes to Pd-PEPPSI-NHC and Pd-PEPPSI-PR3 pre-catalysts. CHEMICAL COMMUNICATIONS, 56(44), 5953–5956. https://doi.org/10.1039/d0cc02262d
Chicago author-date
Guillet, Sébastien, Vladislav Voloshkin, Marina Saab, Marek Beliš, Kristof Van Hecke, Fady Nahra, and Steven Nolan. 2020. “Understanding Existing and Designing Novel Synthetic Routes to Pd-PEPPSI-NHC and Pd-PEPPSI-PR3 Pre-Catalysts.” CHEMICAL COMMUNICATIONS 56 (44): 5953–56. https://doi.org/10.1039/d0cc02262d.
Chicago author-date (all authors)
Guillet, Sébastien, Vladislav Voloshkin, Marina Saab, Marek Beliš, Kristof Van Hecke, Fady Nahra, and Steven Nolan. 2020. “Understanding Existing and Designing Novel Synthetic Routes to Pd-PEPPSI-NHC and Pd-PEPPSI-PR3 Pre-Catalysts.” CHEMICAL COMMUNICATIONS 56 (44): 5953–5956. doi:10.1039/d0cc02262d.
Vancouver
1.
Guillet S, Voloshkin V, Saab M, Beliš M, Van Hecke K, Nahra F, et al. Understanding existing and designing novel synthetic routes to Pd-PEPPSI-NHC and Pd-PEPPSI-PR3 pre-catalysts. CHEMICAL COMMUNICATIONS. 2020;56(44):5953–6.
IEEE
[1]
S. Guillet et al., “Understanding existing and designing novel synthetic routes to Pd-PEPPSI-NHC and Pd-PEPPSI-PR3 pre-catalysts,” CHEMICAL COMMUNICATIONS, vol. 56, no. 44, pp. 5953–5956, 2020.
@article{8688115,
  abstract     = {The reaction mechanism leading to the formation of cross-coupling palladium pre-catalysts of the PEPPSI family was investigated. Two intermediates were isolated and proved to be both suitable synthons to the pre-catalysts, with one permitting the design of a novel and greener user-friendly synthetic route. In light of this mechanistic understanding, the traditional one-pot method was shown to be possible using stoichiometric amounts of throw-away ligand, which represents a considerable synthetic improvement over the wasteful "in pyridine" approach.},
  author       = {Guillet, Sébastien and Voloshkin, Vladislav and Saab, Marina and Beliš, Marek and Van Hecke, Kristof and Nahra, Fady and Nolan, Steven},
  issn         = {1359-7345},
  journal      = {CHEMICAL COMMUNICATIONS},
  keywords     = {N-HETEROCYCLIC CARBENE,CROSS-COUPLING REACTION,COMPLEXES SYNTHESIS,ARYL HALIDES,AMINATION,PD-PEPPSI-IPENT(CL),PRECATALYST,IPENT},
  language     = {eng},
  number       = {44},
  pages        = {5953--5956},
  publisher    = {Royal Soc Chemistry},
  title        = {Understanding existing and designing novel synthetic routes to Pd-PEPPSI-NHC and Pd-PEPPSI-PR3 pre-catalysts},
  url          = {http://dx.doi.org/10.1039/d0cc02262d},
  volume       = {56},
  year         = {2020},
}

Altmetric
View in Altmetric
Web of Science
Times cited: