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Acid-base disturbances in dehydrated patients with cystic fibrosis : four case reports with review of literature

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Abstract
Most episodes of vomiting, reduced intake and diarrhoea in children can be evaluated and treated without additional tests. However, when the degree of clinical dehydration is not in line with the patient's medical history, other diagnoses should be suspected. In the presence of a hyponatraemic hypochloraemic metabolic alkalosis, cystic fibrosis (CF) should be included in the differential diagnosis, especially if there is failure to thrive even in the absence of respiratory symptoms. Furthermore, young patients diagnosed with CF have a higher risk for an acute electrolyte decompensation caused by increased salt and fluid losses. We present 4 paediatric cases to raise the awareness of electrolyte disturbances in CF patients.
Keywords
METABOLIC ALKALOSIS, INFANTS, CHILDREN, HYPOELECTROLYTEMIA, GUIDELINES, EXERCISE, Hyponatraemic hypochloraemic alkalosis, cystic fibrosis, dehydration, electrolyte disturbances, pseudo-Bartter

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Citation

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MLA
Peremans, Lieselot, et al. “Acid-Base Disturbances in Dehydrated Patients with Cystic Fibrosis : Four Case Reports with Review of Literature.” ACTA GASTRO-ENTEROLOGICA BELGICA, vol. 83, no. 2, 2020, pp. 315–18.
APA
Peremans, L., Declercq, D., Vande Velde, S., De Bruyne, R., Van Winckel, M., Vande Walle, J., & Van Biervliet, S. (2020). Acid-base disturbances in dehydrated patients with cystic fibrosis : four case reports with review of literature. ACTA GASTRO-ENTEROLOGICA BELGICA, 83(2), 315–318.
Chicago author-date
Peremans, Lieselot, Dimitri Declercq, Saskia Vande Velde, Ruth De Bruyne, Myriam Van Winckel, Johan Vande Walle, and Stephanie Van Biervliet. 2020. “Acid-Base Disturbances in Dehydrated Patients with Cystic Fibrosis : Four Case Reports with Review of Literature.” ACTA GASTRO-ENTEROLOGICA BELGICA 83 (2): 315–18.
Chicago author-date (all authors)
Peremans, Lieselot, Dimitri Declercq, Saskia Vande Velde, Ruth De Bruyne, Myriam Van Winckel, Johan Vande Walle, and Stephanie Van Biervliet. 2020. “Acid-Base Disturbances in Dehydrated Patients with Cystic Fibrosis : Four Case Reports with Review of Literature.” ACTA GASTRO-ENTEROLOGICA BELGICA 83 (2): 315–318.
Vancouver
1.
Peremans L, Declercq D, Vande Velde S, De Bruyne R, Van Winckel M, Vande Walle J, et al. Acid-base disturbances in dehydrated patients with cystic fibrosis : four case reports with review of literature. ACTA GASTRO-ENTEROLOGICA BELGICA. 2020;83(2):315–8.
IEEE
[1]
L. Peremans et al., “Acid-base disturbances in dehydrated patients with cystic fibrosis : four case reports with review of literature,” ACTA GASTRO-ENTEROLOGICA BELGICA, vol. 83, no. 2, pp. 315–318, 2020.
@article{8682642,
  abstract     = {{Most episodes of vomiting, reduced intake and diarrhoea in children can be evaluated and treated without additional tests. However, when the degree of clinical dehydration is not in line with the patient's medical history, other diagnoses should be suspected. In the presence of a hyponatraemic hypochloraemic metabolic alkalosis, cystic fibrosis (CF) should be included in the differential diagnosis, especially if there is failure to thrive even in the absence of respiratory symptoms. Furthermore, young patients diagnosed with CF have a higher risk for an acute electrolyte decompensation caused by increased salt and fluid losses. We present 4 paediatric cases to raise the awareness of electrolyte disturbances in CF patients.}},
  author       = {{Peremans, Lieselot and Declercq, Dimitri and Vande Velde, Saskia and De Bruyne, Ruth and Van Winckel, Myriam and Vande Walle, Johan and Van Biervliet, Stephanie}},
  issn         = {{1784-3227}},
  journal      = {{ACTA GASTRO-ENTEROLOGICA BELGICA}},
  keywords     = {{METABOLIC ALKALOSIS,INFANTS,CHILDREN,HYPOELECTROLYTEMIA,GUIDELINES,EXERCISE,Hyponatraemic hypochloraemic alkalosis,cystic fibrosis,dehydration,electrolyte disturbances,pseudo-Bartter}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{315--318}},
  title        = {{Acid-base disturbances in dehydrated patients with cystic fibrosis : four case reports with review of literature}},
  url          = {{https://www.ageb.be/ageb-journal/ageb-volume/ageb-article/1796/}},
  volume       = {{83}},
  year         = {{2020}},
}

Web of Science
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