Health economic evaluation of an influenza vaccination program to prevent sick leave in employees : a prospective cohort study
- Author
- Nathanael Lutz, Tom Deliens, Peter Clarys, Nick Verhaeghe (UGent) and Jan Taeymans
- Organization
- Abstract
- Objective: To evaluate the cost-effectiveness of an influenza vaccination program (IVP) among employees. Methods: This health economic evaluation was embedded in a prospective cohort study of a voluntary IVP. Data on incidence, direct, and indirect costs were collected via questionnaires. Boot-strapping and modeling techniques were used to assess uncertainty of the results. Results: In the base-scenario, the IVP was less effective, more expensive and thus, neither cost-effective nor cost-beneficial. When applying a sensitivity analysis using published estimates of IVP effectiveness on the data, the IVP became cost-effective and cost-beneficial. Conclusions: Like in many evaluations of real-world settings, lack of randomization may have caused selection bias which may explain the surprising results of the main analysis. This indicates the importance of sensitivity analyses and modeling approaches for future studies assessing the cost-effectiveness of IVP in a real-world setting.
- Keywords
- Environmental and Occupational Health, economic evaluation, influenza vaccination, prevention, sick leave, worksite health promotion, WORKING ADULTS, COST-EFFECTIVENESS, SEASONAL INFLUENZA, PUBLIC-HEALTH, PRODUCTIVITY, IMPACT, BENEFIT, US
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-8682100
- MLA
- Lutz, Nathanael, et al. “Health Economic Evaluation of an Influenza Vaccination Program to Prevent Sick Leave in Employees : A Prospective Cohort Study.” JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, vol. 62, no. 8, 2020, pp. 549–56, doi:10.1097/jom.0000000000001878.
- APA
- Lutz, N., Deliens, T., Clarys, P., Verhaeghe, N., & Taeymans, J. (2020). Health economic evaluation of an influenza vaccination program to prevent sick leave in employees : a prospective cohort study. JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 62(8), 549–556. https://doi.org/10.1097/jom.0000000000001878
- Chicago author-date
- Lutz, Nathanael, Tom Deliens, Peter Clarys, Nick Verhaeghe, and Jan Taeymans. 2020. “Health Economic Evaluation of an Influenza Vaccination Program to Prevent Sick Leave in Employees : A Prospective Cohort Study.” JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE 62 (8): 549–56. https://doi.org/10.1097/jom.0000000000001878.
- Chicago author-date (all authors)
- Lutz, Nathanael, Tom Deliens, Peter Clarys, Nick Verhaeghe, and Jan Taeymans. 2020. “Health Economic Evaluation of an Influenza Vaccination Program to Prevent Sick Leave in Employees : A Prospective Cohort Study.” JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE 62 (8): 549–556. doi:10.1097/jom.0000000000001878.
- Vancouver
- 1.Lutz N, Deliens T, Clarys P, Verhaeghe N, Taeymans J. Health economic evaluation of an influenza vaccination program to prevent sick leave in employees : a prospective cohort study. JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE. 2020;62(8):549–56.
- IEEE
- [1]N. Lutz, T. Deliens, P. Clarys, N. Verhaeghe, and J. Taeymans, “Health economic evaluation of an influenza vaccination program to prevent sick leave in employees : a prospective cohort study,” JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, vol. 62, no. 8, pp. 549–556, 2020.
@article{8682100,
abstract = {{Objective: To evaluate the cost-effectiveness of an influenza vaccination program (IVP) among employees. Methods: This health economic evaluation was embedded in a prospective cohort study of a voluntary IVP. Data on incidence, direct, and indirect costs were collected via questionnaires. Boot-strapping and modeling techniques were used to assess uncertainty of the results. Results: In the base-scenario, the IVP was less effective, more expensive and thus, neither cost-effective nor cost-beneficial. When applying a sensitivity analysis using published estimates of IVP effectiveness on the data, the IVP became cost-effective and cost-beneficial. Conclusions: Like in many evaluations of real-world settings, lack of randomization may have caused selection bias which may explain the surprising results of the main analysis. This indicates the importance of sensitivity analyses and modeling approaches for future studies assessing the cost-effectiveness of IVP in a real-world setting.}},
author = {{Lutz, Nathanael and Deliens, Tom and Clarys, Peter and Verhaeghe, Nick and Taeymans, Jan}},
issn = {{1076-2752}},
journal = {{JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE}},
keywords = {{Environmental and Occupational Health,economic evaluation,influenza vaccination,prevention,sick leave,worksite health promotion,WORKING ADULTS,COST-EFFECTIVENESS,SEASONAL INFLUENZA,PUBLIC-HEALTH,PRODUCTIVITY,IMPACT,BENEFIT,US}},
language = {{eng}},
number = {{8}},
pages = {{549--556}},
title = {{Health economic evaluation of an influenza vaccination program to prevent sick leave in employees : a prospective cohort study}},
url = {{http://doi.org/10.1097/jom.0000000000001878}},
volume = {{62}},
year = {{2020}},
}
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