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Current status of COVID-19 (pre)clinical vaccine development

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Abstract
The current COVID-19 pandemic has a tremendous impact on daily life world-wide. Despite the ability to dampen the spread of SARS-CoV-2, the causative agent of the diseases, through restrictive interventions, it is believed that only effective vaccines will provide sufficient control over the disease and revert societal live back to normal. At present, a double-digit number of efforts are devoted to the development of a vaccine against COVID-19. Here, we provide an overview of these (pre)clinical efforts and provide background information on the technologies behind these vaccines. In addition, we discuss potential hurdles that need to be addressed prior to mass scale clinical translation of successful vaccine candidates.
Keywords
COVID-19, pandemic, SARS-CoV-2, vaccine, VIRUS-LIKE PARTICLES, MESSENGER-RNA VACCINES, INFLUENZA VACCINE, IMMUNE-RESPONSES, DELIVERY-SYSTEMS, SARS-COV, IMMUNOGENICITY, PROTEIN, DNA, PROTECTION

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Citation

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MLA
Ye, Tingting, et al. “Current Status of COVID-19 (Pre)Clinical Vaccine Development.” ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, edited by Tingting Ye, vol. 59, no. 43, 2020, pp. 18885–97, doi:10.1002/anie.202008319.
APA
Ye, T., Zhong, Z., Garcia-Sastre, A., Schotsaert, M., & De Geest, B. (2020). Current status of COVID-19 (pre)clinical vaccine development. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 59(43), 18885–18897. https://doi.org/10.1002/anie.202008319
Chicago author-date
Ye, Tingting, Zifu Zhong, Adolfo Garcia-Sastre, Michael Schotsaert, and Bruno De Geest. 2020. “Current Status of COVID-19 (Pre)Clinical Vaccine Development.” Edited by Tingting Ye. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 59 (43): 18885–97. https://doi.org/10.1002/anie.202008319.
Chicago author-date (all authors)
Ye, Tingting, Zifu Zhong, Adolfo Garcia-Sastre, Michael Schotsaert, and Bruno De Geest. 2020. “Current Status of COVID-19 (Pre)Clinical Vaccine Development.” Ed by. Tingting Ye. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 59 (43): 18885–18897. doi:10.1002/anie.202008319.
Vancouver
1.
Ye T, Zhong Z, Garcia-Sastre A, Schotsaert M, De Geest B. Current status of COVID-19 (pre)clinical vaccine development. Ye T, editor. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2020;59(43):18885–97.
IEEE
[1]
T. Ye, Z. Zhong, A. Garcia-Sastre, M. Schotsaert, and B. De Geest, “Current status of COVID-19 (pre)clinical vaccine development,” ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 59, no. 43, pp. 18885–18897, 2020.
@article{8680726,
  abstract     = {{The current COVID-19 pandemic has a tremendous impact on daily life world-wide. Despite the ability to dampen the spread of SARS-CoV-2, the causative agent of the diseases, through restrictive interventions, it is believed that only effective vaccines will provide sufficient control over the disease and revert societal live back to normal. At present, a double-digit number of efforts are devoted to the development of a vaccine against COVID-19. Here, we provide an overview of these (pre)clinical efforts and provide background information on the technologies behind these vaccines. In addition, we discuss potential hurdles that need to be addressed prior to mass scale clinical translation of successful vaccine candidates.}},
  author       = {{Ye, Tingting and Zhong, Zifu and Garcia-Sastre, Adolfo and Schotsaert, Michael and De Geest, Bruno}},
  editor       = {{Ye, Tingting}},
  issn         = {{1433-7851}},
  journal      = {{ANGEWANDTE CHEMIE-INTERNATIONAL EDITION}},
  keywords     = {{COVID-19,pandemic,SARS-CoV-2,vaccine,VIRUS-LIKE PARTICLES,MESSENGER-RNA VACCINES,INFLUENZA VACCINE,IMMUNE-RESPONSES,DELIVERY-SYSTEMS,SARS-COV,IMMUNOGENICITY,PROTEIN,DNA,PROTECTION}},
  language     = {{eng}},
  number       = {{43}},
  pages        = {{18885--18897}},
  title        = {{Current status of COVID-19 (pre)clinical vaccine development}},
  url          = {{http://doi.org/10.1002/anie.202008319}},
  volume       = {{59}},
  year         = {{2020}},
}

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