Evaluation of group vaccination of sows and gilts against Salmonella Typhimurium with an attenuated vaccine in subclinically infected pig herds
- Author
- Linda Peeters, Jeroen Dewulf (UGent) , Filip Boyen (UGent) , C. Brosse, T. Vandersmissen, G. Rasschaert, Marc Heyndrickx (UGent) , M. Cargnel, W. Mattheus, Frank Pasmans (UGent) , Freddy Haesebrouck (UGent) and Dominiek Maes (UGent)
- Organization
- Abstract
- Subclinical Salmonella Typhimurium infections occur frequently in pigs and constitute a major risk for human salmonellosis. With the currently available control measures, Salmonella Typhimurium infections in pigs remain difficult to control. Vaccination has been proposed to be an effective tool to control infections at farm level. In the current study, the effect of group vaccination of sows and gilts against Salmonella Typhimurium is evaluated on Salmonella prevalence in fecal and overshoe samples and ileocecal lymph nodes, and on serology in the sows and their offspring in three subclinically infected pig farms. In each farm, all sows and gilts were vaccinated twice, three weeks apart, with an attenuated histidineadenine auxotrophic vaccine (Salmoporc (R), IDT Biologika). From three months after the group vaccination onwards, all sows were given a booster dose three weeks before every farrowing. The farms were monitored bacteriologically and serologically from 12 months before until 15 months after the group vaccination. After group vaccination, no significant effect was detected in the prevalence of Salmonella Typhimurium in the fecal and overshoe samples collected in the sows (before: 2 %, after: 0 %) and their offspring at 18 weeks (before: 17 %, after: 11 %) and at 26 weeks of age (before: 15 %, after: 7 %), and when combining the results of the offspring at 18 and 26 weeks of age (before: 16 %, after: 9 %). Also, no significant effect was detected in the prevalence of Salmonella Typhimurium positive lymph nodes of sows (before and after: 0 %) and their offspring (before: 4 %, after: 7 %). Regarding serology, the mean S/P-ratios of the sows were significantly higher after the group vaccination, compared to before group vaccination (before: 1.50, after: 2.32, p < 0.001). The mean S/P-ratios of the offspring at slaughter age were significantly lower after the group vaccination, compared to before group vaccination (before: 1.71, after: 1.04, p = 0.001). In conclusion, group vaccination of sows and gilts resulted in a more beneficial serological status of the offspring, but did not significantly decrease Salmonella Typhimurium excretion and lymph node contamination.
- Keywords
- Salmonella Typhimurium, Bacteriology, Serology, Swine, Vaccination, NON-TYPHOIDAL SALMONELLA, ENVIRONMENTAL CONTAMINATION, SWINE, ENTERICA, LAIRAGE, INTERVENTIONS, SLAUGHTER, EFFICACY, LIVE, COLONIZATION
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-8680245
- MLA
- Peeters, Linda, et al. “Evaluation of Group Vaccination of Sows and Gilts against Salmonella Typhimurium with an Attenuated Vaccine in Subclinically Infected Pig Herds.” PREVENTIVE VETERINARY MEDICINE, vol. 182, 2020, doi:10.1016/j.prevetmed.2020.104884.
- APA
- Peeters, L., Dewulf, J., Boyen, F., Brosse, C., Vandersmissen, T., Rasschaert, G., … Maes, D. (2020). Evaluation of group vaccination of sows and gilts against Salmonella Typhimurium with an attenuated vaccine in subclinically infected pig herds. PREVENTIVE VETERINARY MEDICINE, 182. https://doi.org/10.1016/j.prevetmed.2020.104884
- Chicago author-date
- Peeters, Linda, Jeroen Dewulf, Filip Boyen, C. Brosse, T. Vandersmissen, G. Rasschaert, Marc Heyndrickx, et al. 2020. “Evaluation of Group Vaccination of Sows and Gilts against Salmonella Typhimurium with an Attenuated Vaccine in Subclinically Infected Pig Herds.” PREVENTIVE VETERINARY MEDICINE 182. https://doi.org/10.1016/j.prevetmed.2020.104884.
- Chicago author-date (all authors)
- Peeters, Linda, Jeroen Dewulf, Filip Boyen, C. Brosse, T. Vandersmissen, G. Rasschaert, Marc Heyndrickx, M. Cargnel, W. Mattheus, Frank Pasmans, Freddy Haesebrouck, and Dominiek Maes. 2020. “Evaluation of Group Vaccination of Sows and Gilts against Salmonella Typhimurium with an Attenuated Vaccine in Subclinically Infected Pig Herds.” PREVENTIVE VETERINARY MEDICINE 182. doi:10.1016/j.prevetmed.2020.104884.
- Vancouver
- 1.Peeters L, Dewulf J, Boyen F, Brosse C, Vandersmissen T, Rasschaert G, et al. Evaluation of group vaccination of sows and gilts against Salmonella Typhimurium with an attenuated vaccine in subclinically infected pig herds. PREVENTIVE VETERINARY MEDICINE. 2020;182.
- IEEE
- [1]L. Peeters et al., “Evaluation of group vaccination of sows and gilts against Salmonella Typhimurium with an attenuated vaccine in subclinically infected pig herds,” PREVENTIVE VETERINARY MEDICINE, vol. 182, 2020.
@article{8680245, abstract = {{Subclinical Salmonella Typhimurium infections occur frequently in pigs and constitute a major risk for human salmonellosis. With the currently available control measures, Salmonella Typhimurium infections in pigs remain difficult to control. Vaccination has been proposed to be an effective tool to control infections at farm level. In the current study, the effect of group vaccination of sows and gilts against Salmonella Typhimurium is evaluated on Salmonella prevalence in fecal and overshoe samples and ileocecal lymph nodes, and on serology in the sows and their offspring in three subclinically infected pig farms. In each farm, all sows and gilts were vaccinated twice, three weeks apart, with an attenuated histidineadenine auxotrophic vaccine (Salmoporc (R), IDT Biologika). From three months after the group vaccination onwards, all sows were given a booster dose three weeks before every farrowing. The farms were monitored bacteriologically and serologically from 12 months before until 15 months after the group vaccination. After group vaccination, no significant effect was detected in the prevalence of Salmonella Typhimurium in the fecal and overshoe samples collected in the sows (before: 2 %, after: 0 %) and their offspring at 18 weeks (before: 17 %, after: 11 %) and at 26 weeks of age (before: 15 %, after: 7 %), and when combining the results of the offspring at 18 and 26 weeks of age (before: 16 %, after: 9 %). Also, no significant effect was detected in the prevalence of Salmonella Typhimurium positive lymph nodes of sows (before and after: 0 %) and their offspring (before: 4 %, after: 7 %). Regarding serology, the mean S/P-ratios of the sows were significantly higher after the group vaccination, compared to before group vaccination (before: 1.50, after: 2.32, p < 0.001). The mean S/P-ratios of the offspring at slaughter age were significantly lower after the group vaccination, compared to before group vaccination (before: 1.71, after: 1.04, p = 0.001). In conclusion, group vaccination of sows and gilts resulted in a more beneficial serological status of the offspring, but did not significantly decrease Salmonella Typhimurium excretion and lymph node contamination.}}, articleno = {{104884}}, author = {{Peeters, Linda and Dewulf, Jeroen and Boyen, Filip and Brosse, C. and Vandersmissen, T. and Rasschaert, G. and Heyndrickx, Marc and Cargnel, M. and Mattheus, W. and Pasmans, Frank and Haesebrouck, Freddy and Maes, Dominiek}}, issn = {{0167-5877}}, journal = {{PREVENTIVE VETERINARY MEDICINE}}, keywords = {{Salmonella Typhimurium,Bacteriology,Serology,Swine,Vaccination,NON-TYPHOIDAL SALMONELLA,ENVIRONMENTAL CONTAMINATION,SWINE,ENTERICA,LAIRAGE,INTERVENTIONS,SLAUGHTER,EFFICACY,LIVE,COLONIZATION}}, language = {{eng}}, pages = {{9}}, title = {{Evaluation of group vaccination of sows and gilts against Salmonella Typhimurium with an attenuated vaccine in subclinically infected pig herds}}, url = {{http://doi.org/10.1016/j.prevetmed.2020.104884}}, volume = {{182}}, year = {{2020}}, }
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