
A direct comparison of natural and acoustic-radiation-force-induced cardiac mechanical waves
- Author
- Lana B. H. Keijzer, Annette Caenen (UGent) , Jason Voorneveld, Mihai Strachinaru, Daniel J. Bowen, Jens van de Wouw, Oana Sorop, Daphne Merkus, Dirk J. Duncker, Antonius F. W. van der Steen, Nico de Jong, Johan G. Bosch and Hendrik J. Vos
- Organization
- Abstract
- Natural and active shear wave elastography (SWE) are potential ultrasound-based techniques to non-invasively assess myocardial stiffness, which could improve current diagnosis of heart failure. This study aims to bridge the knowledge gap between both techniques and discuss their respective impacts on cardiac stiffness evaluation. We recorded the mechanical waves occurring after aortic and mitral valve closure (AVC, MVC) and those induced by acoustic radiation force throughout the cardiac cycle in four pigs after sternotomy. Natural SWE showed a higher feasibility than active SWE, which is an advantage for clinical application. Median propagation speeds of 2.5–4.0 m/s and 1.6–4.0 m/s were obtained after AVC and MVC, whereas ARF-based median speeds of 0.9–1.2 m/s and 2.1–3.8 m/s were reported for diastole and systole, respectively. The different wave characteristics in both methods, such as the frequency content, complicate the direct comparison of waves. Nevertheless, a good match was found in propagation speeds between natural and active SWE at the moment of valve closure, and the natural waves showed higher propagation speeds than in diastole. Furthermore, the results demonstrated that the natural waves occur in between diastole and systole identified with active SWE, and thus represent a myocardial stiffness in between relaxation and contraction.
- Keywords
- Multidisciplinary, MYOCARDIAL STIFFNESS, DIASTOLIC FUNCTION, RISK-FACTORS, ELASTOGRAPHY, ECHOCARDIOGRAPHY, POPULATION, PERFUSION, UPDATE, MODEL
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-8680115
- MLA
- Keijzer, Lana B. H., et al. “A Direct Comparison of Natural and Acoustic-Radiation-Force-Induced Cardiac Mechanical Waves.” SCIENTIFIC REPORTS, vol. 10, 2020, doi:10.1038/s41598-020-75401-1.
- APA
- Keijzer, L. B. H., Caenen, A., Voorneveld, J., Strachinaru, M., Bowen, D. J., van de Wouw, J., … Vos, H. J. (2020). A direct comparison of natural and acoustic-radiation-force-induced cardiac mechanical waves. SCIENTIFIC REPORTS, 10. https://doi.org/10.1038/s41598-020-75401-1
- Chicago author-date
- Keijzer, Lana B. H., Annette Caenen, Jason Voorneveld, Mihai Strachinaru, Daniel J. Bowen, Jens van de Wouw, Oana Sorop, et al. 2020. “A Direct Comparison of Natural and Acoustic-Radiation-Force-Induced Cardiac Mechanical Waves.” SCIENTIFIC REPORTS 10. https://doi.org/10.1038/s41598-020-75401-1.
- Chicago author-date (all authors)
- Keijzer, Lana B. H., Annette Caenen, Jason Voorneveld, Mihai Strachinaru, Daniel J. Bowen, Jens van de Wouw, Oana Sorop, Daphne Merkus, Dirk J. Duncker, Antonius F. W. van der Steen, Nico de Jong, Johan G. Bosch, and Hendrik J. Vos. 2020. “A Direct Comparison of Natural and Acoustic-Radiation-Force-Induced Cardiac Mechanical Waves.” SCIENTIFIC REPORTS 10. doi:10.1038/s41598-020-75401-1.
- Vancouver
- 1.Keijzer LBH, Caenen A, Voorneveld J, Strachinaru M, Bowen DJ, van de Wouw J, et al. A direct comparison of natural and acoustic-radiation-force-induced cardiac mechanical waves. SCIENTIFIC REPORTS. 2020;10.
- IEEE
- [1]L. B. H. Keijzer et al., “A direct comparison of natural and acoustic-radiation-force-induced cardiac mechanical waves,” SCIENTIFIC REPORTS, vol. 10, 2020.
@article{8680115, abstract = {{Natural and active shear wave elastography (SWE) are potential ultrasound-based techniques to non-invasively assess myocardial stiffness, which could improve current diagnosis of heart failure. This study aims to bridge the knowledge gap between both techniques and discuss their respective impacts on cardiac stiffness evaluation. We recorded the mechanical waves occurring after aortic and mitral valve closure (AVC, MVC) and those induced by acoustic radiation force throughout the cardiac cycle in four pigs after sternotomy. Natural SWE showed a higher feasibility than active SWE, which is an advantage for clinical application. Median propagation speeds of 2.5–4.0 m/s and 1.6–4.0 m/s were obtained after AVC and MVC, whereas ARF-based median speeds of 0.9–1.2 m/s and 2.1–3.8 m/s were reported for diastole and systole, respectively. The different wave characteristics in both methods, such as the frequency content, complicate the direct comparison of waves. Nevertheless, a good match was found in propagation speeds between natural and active SWE at the moment of valve closure, and the natural waves showed higher propagation speeds than in diastole. Furthermore, the results demonstrated that the natural waves occur in between diastole and systole identified with active SWE, and thus represent a myocardial stiffness in between relaxation and contraction.}}, articleno = {{18431}}, author = {{Keijzer, Lana B. H. and Caenen, Annette and Voorneveld, Jason and Strachinaru, Mihai and Bowen, Daniel J. and van de Wouw, Jens and Sorop, Oana and Merkus, Daphne and Duncker, Dirk J. and van der Steen, Antonius F. W. and de Jong, Nico and Bosch, Johan G. and Vos, Hendrik J.}}, issn = {{2045-2322}}, journal = {{SCIENTIFIC REPORTS}}, keywords = {{Multidisciplinary,MYOCARDIAL STIFFNESS,DIASTOLIC FUNCTION,RISK-FACTORS,ELASTOGRAPHY,ECHOCARDIOGRAPHY,POPULATION,PERFUSION,UPDATE,MODEL}}, language = {{eng}}, pages = {{15}}, title = {{A direct comparison of natural and acoustic-radiation-force-induced cardiac mechanical waves}}, url = {{http://doi.org/10.1038/s41598-020-75401-1}}, volume = {{10}}, year = {{2020}}, }
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