Advanced search
1 file | 2.15 MB Add to list

Obstetrical characteristics and neonatal outcome according to aetiology of preterm birth : a cohort study

Isabelle Dehaene (UGent) , Eline Scheire (UGent) , Johan Steen (UGent) , Kris De Coen (UGent) , Johan Decruyenaere (UGent) , Koenraad Smets (UGent) and Kristien Roelens (UGent)
Author
Organization
Abstract
Purpose Preterm birth (PTB) can be categorised according to aetiology into: spontaneous preterm labour (SPL), preterm prelabour rupture of membranes (PPROM), and iatrogenic (iatro) PTB. Outcomes could differ between these groups, which could be of interest in counselling. We aimed to explore differences between aetiologic groups of PTB in maternal demographics, obstetrical characteristics and management, and neonatal outcomes. Methods This is a cohort study (2012-2018) in Ghent University Hospital, Belgium, of deliveries from 24 + 0 to 33 + 6 weeks. We compared perinatal demographics, management, and outcomes between the aetiologic types of PTB. Point and interval estimates for differences between aetiologic types were estimated using a Generalised Estimating Equations approach to handle clustering due to multiple gestations. Results 813 mothers and 987 neonates were included. Prevalences of different aetiologic types of PTB were similar. Maternal BMI was higher in the iatrogenic group (iatro-SPL: + 1.92 kg/m(2), 95% CI 1.02, 2.83; iatro-PPROM: + 2.06 kg/m(2), 95% CI 1.15, 2.96). There was an inversed sex ratio (0.82, 95% CI 0.65, 1.03), more growth restriction (iatro-SPL: + 22.60%, 95% CI 17.08, 28.13; iatro-PPROM: + 24.64%, 95% CI 19.44, 29.83), and a higher caesarean section rate in the iatrogenic group (iatro-SPL: + 57.23%, 95% CI 50.32, 64.13, iatro-PPROM: + 56.79%, 95% CI 50.20, 63.38) and more patients received at least one complete course of antenatal corticosteroids (iatro-SPL: + 17.60%, 95% CI 10.60, 24.60, iatro-PPROM: + 10.73%, 95% CI 4.52, 16.94). In all types of PTB, adverse neonatal outcomes had a low prevalence, except for respiratory distress syndrome. A composite of adverse neonatal outcome was more prevalent in the SPL- compared to the PPROM group, and there was less intraventricular haemorrhage in the iatrogenic group. Conclusion Additional to gestational age at birth, the aetiology of PTB is associated with neonatal outcome. More data are needed to enable individualised management and counselling in case of threatened PTB.
Keywords
Obstetrics and Gynaecology, General Medicine, Premature birth [MeSH], Infant, Premature [MeSH], Pregnancy complications [MeSH], Biostatistics [MeSH], DELIVERY ONSET, FETAL GENDER, MORTALITY, EPIDEMIOLOGY, TOCOLYSIS

Downloads

  • (...).pdf
    • full text (Published version)
    • |
    • UGent only
    • |
    • PDF
    • |
    • 2.15 MB

Citation

Please use this url to cite or link to this publication:

MLA
Dehaene, Isabelle, et al. “Obstetrical Characteristics and Neonatal Outcome According to Aetiology of Preterm Birth : A Cohort Study.” ARCHIVES OF GYNECOLOGY AND OBSTETRICS, vol. 302, no. 4, 2020, pp. 861–71, doi:10.1007/s00404-020-05673-5.
APA
Dehaene, I., Scheire, E., Steen, J., De Coen, K., Decruyenaere, J., Smets, K., & Roelens, K. (2020). Obstetrical characteristics and neonatal outcome according to aetiology of preterm birth : a cohort study. ARCHIVES OF GYNECOLOGY AND OBSTETRICS, 302(4), 861–871. https://doi.org/10.1007/s00404-020-05673-5
Chicago author-date
Dehaene, Isabelle, Eline Scheire, Johan Steen, Kris De Coen, Johan Decruyenaere, Koenraad Smets, and Kristien Roelens. 2020. “Obstetrical Characteristics and Neonatal Outcome According to Aetiology of Preterm Birth : A Cohort Study.” ARCHIVES OF GYNECOLOGY AND OBSTETRICS 302 (4): 861–71. https://doi.org/10.1007/s00404-020-05673-5.
Chicago author-date (all authors)
Dehaene, Isabelle, Eline Scheire, Johan Steen, Kris De Coen, Johan Decruyenaere, Koenraad Smets, and Kristien Roelens. 2020. “Obstetrical Characteristics and Neonatal Outcome According to Aetiology of Preterm Birth : A Cohort Study.” ARCHIVES OF GYNECOLOGY AND OBSTETRICS 302 (4): 861–871. doi:10.1007/s00404-020-05673-5.
Vancouver
1.
Dehaene I, Scheire E, Steen J, De Coen K, Decruyenaere J, Smets K, et al. Obstetrical characteristics and neonatal outcome according to aetiology of preterm birth : a cohort study. ARCHIVES OF GYNECOLOGY AND OBSTETRICS. 2020;302(4):861–71.
IEEE
[1]
I. Dehaene et al., “Obstetrical characteristics and neonatal outcome according to aetiology of preterm birth : a cohort study,” ARCHIVES OF GYNECOLOGY AND OBSTETRICS, vol. 302, no. 4, pp. 861–871, 2020.
@article{8669889,
  abstract     = {{Purpose Preterm birth (PTB) can be categorised according to aetiology into: spontaneous preterm labour (SPL), preterm prelabour rupture of membranes (PPROM), and iatrogenic (iatro) PTB. Outcomes could differ between these groups, which could be of interest in counselling. We aimed to explore differences between aetiologic groups of PTB in maternal demographics, obstetrical characteristics and management, and neonatal outcomes. Methods This is a cohort study (2012-2018) in Ghent University Hospital, Belgium, of deliveries from 24 + 0 to 33 + 6 weeks. We compared perinatal demographics, management, and outcomes between the aetiologic types of PTB. Point and interval estimates for differences between aetiologic types were estimated using a Generalised Estimating Equations approach to handle clustering due to multiple gestations. Results 813 mothers and 987 neonates were included. Prevalences of different aetiologic types of PTB were similar. Maternal BMI was higher in the iatrogenic group (iatro-SPL: + 1.92 kg/m(2), 95% CI 1.02, 2.83; iatro-PPROM: + 2.06 kg/m(2), 95% CI 1.15, 2.96). There was an inversed sex ratio (0.82, 95% CI 0.65, 1.03), more growth restriction (iatro-SPL: + 22.60%, 95% CI 17.08, 28.13; iatro-PPROM: + 24.64%, 95% CI 19.44, 29.83), and a higher caesarean section rate in the iatrogenic group (iatro-SPL: + 57.23%, 95% CI 50.32, 64.13, iatro-PPROM: + 56.79%, 95% CI 50.20, 63.38) and more patients received at least one complete course of antenatal corticosteroids (iatro-SPL: + 17.60%, 95% CI 10.60, 24.60, iatro-PPROM: + 10.73%, 95% CI 4.52, 16.94). In all types of PTB, adverse neonatal outcomes had a low prevalence, except for respiratory distress syndrome. A composite of adverse neonatal outcome was more prevalent in the SPL- compared to the PPROM group, and there was less intraventricular haemorrhage in the iatrogenic group. Conclusion Additional to gestational age at birth, the aetiology of PTB is associated with neonatal outcome. More data are needed to enable individualised management and counselling in case of threatened PTB.}},
  author       = {{Dehaene, Isabelle and Scheire, Eline and Steen, Johan and De Coen, Kris and Decruyenaere, Johan and Smets, Koenraad and Roelens, Kristien}},
  issn         = {{0932-0067}},
  journal      = {{ARCHIVES OF GYNECOLOGY AND OBSTETRICS}},
  keywords     = {{Obstetrics and Gynaecology,General Medicine,Premature birth [MeSH],Infant,Premature [MeSH],Pregnancy complications [MeSH],Biostatistics [MeSH],DELIVERY ONSET,FETAL GENDER,MORTALITY,EPIDEMIOLOGY,TOCOLYSIS}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{861--871}},
  title        = {{Obstetrical characteristics and neonatal outcome according to aetiology of preterm birth : a cohort study}},
  url          = {{http://dx.doi.org/10.1007/s00404-020-05673-5}},
  volume       = {{302}},
  year         = {{2020}},
}

Altmetric
View in Altmetric
Web of Science
Times cited: