Advanced search
1 file | 1.26 MB Add to list

Do population near the coast have a lower lung cancer incidence rate?

Zixia Liu (UGent) , Colin Janssen (UGent) and Jana Asselman (UGent)
(2020)
Author
Organization
Abstract
There are shreds of epidemiological data suggesting that living by the sea can have positive effects on human health, but the causal factors are still unknown. In recent years, a new hypothesis proposed by Moore (2015) suggested that bioactive molecules in the sea spray aerosol may benefit human health through interaction with the mTOR pathway. This pathway is related to lung cancer, diabetes, and obesity. Results from in vitro studies with lung cancer cells supported the biogenic hypothesis (Asselman, et al. 2019), but no epidemiological study has been done on this topic so far. In this research, we use the global cancer registry data from the Cancer Incidence in Five Continents (CIX5), to test if a causal relationship between living by the sea and the lung cancer incidence rate exists. We defined the living location based on the coordinates of registry agencies that reported the data and calculate the closest distance to coastline. We then investigated the difference in lung cancer incidence rates between the coastal regions and the inland regions. We observed that on a global scale, the lung cancer incidence rate of the coastal region group is significantly lower than the inland region group (p = 0.02). No statistical linear relationship could be defined for the lung cancer incidence rate globally and the distance from the coastline within ~ 300km range. (R-sqr = 3.1%). In the US, the distance from the coastline can explain up to (R-sqr =) 30.0% of the variation of lung cancer incidence rate. This research investigated the human health effects of SSA from a new perspective. In order to obtain more accurate and convincing epidemiological conclusions, a more detailed survey is needed.
Keywords
Human health, Lung cancer, Biogenics hypothesis

Downloads

  • LiuZixia Poster SOPHIE2020.pdf
    • full text
    • |
    • open access
    • |
    • PDF
    • |
    • 1.26 MB

Citation

Please use this url to cite or link to this publication:

MLA
Liu, Zixia, et al. Do Population near the Coast Have a Lower Lung Cancer Incidence Rate? 2020.
APA
Liu, Z., Janssen, C., & Asselman, J. (2020). Do population near the coast have a lower lung cancer incidence rate? Presented at the SOPHIE2020 People, Health and the Ocean, Brussels.
Chicago author-date
Liu, Zixia, Colin Janssen, and Jana Asselman. 2020. “Do Population near the Coast Have a Lower Lung Cancer Incidence Rate?” In .
Chicago author-date (all authors)
Liu, Zixia, Colin Janssen, and Jana Asselman. 2020. “Do Population near the Coast Have a Lower Lung Cancer Incidence Rate?” In .
Vancouver
1.
Liu Z, Janssen C, Asselman J. Do population near the coast have a lower lung cancer incidence rate? In 2020.
IEEE
[1]
Z. Liu, C. Janssen, and J. Asselman, “Do population near the coast have a lower lung cancer incidence rate?,” presented at the SOPHIE2020 People, Health and the Ocean, Brussels, 2020.
@inproceedings{8668184,
  abstract     = {There are shreds of epidemiological data suggesting that living by the sea can have positive effects on human health, but the causal factors are still unknown.
In recent years, a new hypothesis proposed by Moore (2015) suggested that bioactive molecules in the sea spray aerosol may benefit human health through interaction with the mTOR pathway. This pathway is related to lung cancer, diabetes, and obesity. Results from in vitro studies with lung cancer cells supported the biogenic hypothesis (Asselman, et al. 2019), but no epidemiological study has been done on this topic so far.
In this research, we use the global cancer registry data from the Cancer Incidence in Five Continents (CIX5), to test if a causal relationship between living by the sea and the lung cancer incidence rate exists. We defined the living location based on the coordinates of registry agencies that reported the data and calculate the closest distance to coastline. We then investigated the difference in lung cancer incidence rates between the coastal regions and the inland regions.
We observed that on a global scale, the lung cancer incidence rate of the coastal region group is significantly lower than the inland region group (p = 0.02). No statistical linear relationship could be defined for the lung cancer incidence rate globally and the distance from the coastline within ~ 300km range. (R-sqr = 3.1%). In the US, the distance from the coastline can explain up to (R-sqr =) 30.0% of the variation of lung cancer incidence rate.
This research investigated the human health effects of SSA from a new perspective. In order to obtain more accurate and convincing epidemiological conclusions, a more detailed survey is needed.},
  author       = {Liu, Zixia and Janssen, Colin and Asselman, Jana},
  keywords     = {Human health,Lung cancer,Biogenics hypothesis},
  language     = {und},
  location     = {Brussels},
  title        = {Do population near the coast have a lower lung cancer incidence rate?},
  url          = {https://sophie2020.eu/resources/webinar-posters/},
  year         = {2020},
}