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Colloids-at-surfaces : physicochemical approaches for facilitating cell adhesion on hybrid hydrogels

Anatolii Abalymov (UGent) , Bogdan Parakhonskiy (UGent) and Andre Skirtach (UGent)
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Abstract
Implementation of an effective focal cell adhesion represents a significant challenge because it requires to develop appropriate materials and processes together with assuring that cells would interact with it effectively. Various coatings are under development in the area of biomaterials including hydrogels and polymeric surfaces. Here, we analyse modification of the coatings by colloidal nano- and micro-particles, which effectively modify the surface of soft hydrogel materials, enhance and allow for adjustment of mechanical properties, and enable molecule release capabilities. A classification of such hybrid coatings is presented, where natural and synthetic polymeric coatings are overviewed. These organic coatings are modified by inorganic micro- and nano- particles. Various approaches to the design of such hybrid coatings are overviewed, while additional functionalities such as release of encapsulated biomolecules and enhancement of mechanical properties are highlighted. The developments in this area target effective cell growth, which is shown to be enhanced by the addition of colloidal particles.
Keywords
Colloid and Surface Chemistry, Hydrogels, Mineralisation, Particles, Focal adhesion, Polymers, Hybrid, Colloids, Cells, Nanoparticles, Microparticles

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MLA
Abalymov, Anatolii, et al. “Colloids-at-Surfaces : Physicochemical Approaches for Facilitating Cell Adhesion on Hybrid Hydrogels.” COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, vol. 603, 2020, doi:10.1016/j.colsurfa.2020.125185.
APA
Abalymov, A., Parakhonskiy, B., & Skirtach, A. (2020). Colloids-at-surfaces : physicochemical approaches for facilitating cell adhesion on hybrid hydrogels. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 603. https://doi.org/10.1016/j.colsurfa.2020.125185
Chicago author-date
Abalymov, Anatolii, Bogdan Parakhonskiy, and Andre Skirtach. 2020. “Colloids-at-Surfaces : Physicochemical Approaches for Facilitating Cell Adhesion on Hybrid Hydrogels.” COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS 603. https://doi.org/10.1016/j.colsurfa.2020.125185.
Chicago author-date (all authors)
Abalymov, Anatolii, Bogdan Parakhonskiy, and Andre Skirtach. 2020. “Colloids-at-Surfaces : Physicochemical Approaches for Facilitating Cell Adhesion on Hybrid Hydrogels.” COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS 603. doi:10.1016/j.colsurfa.2020.125185.
Vancouver
1.
Abalymov A, Parakhonskiy B, Skirtach A. Colloids-at-surfaces : physicochemical approaches for facilitating cell adhesion on hybrid hydrogels. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS. 2020;603.
IEEE
[1]
A. Abalymov, B. Parakhonskiy, and A. Skirtach, “Colloids-at-surfaces : physicochemical approaches for facilitating cell adhesion on hybrid hydrogels,” COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, vol. 603, 2020.
@article{8668006,
  abstract     = {{Implementation of an effective focal cell adhesion represents a significant challenge because it requires to develop appropriate materials and processes together with assuring that cells would interact with it effectively. Various coatings are under development in the area of biomaterials including hydrogels and polymeric surfaces. Here, we analyse modification of the coatings by colloidal nano- and micro-particles, which effectively modify the surface of soft hydrogel materials, enhance and allow for adjustment of mechanical properties, and enable molecule release capabilities. A classification of such hybrid coatings is presented, where natural and synthetic polymeric coatings are overviewed. These organic coatings are modified by inorganic micro- and nano- particles. Various approaches to the design of such hybrid coatings are overviewed, while additional functionalities such as release of encapsulated biomolecules and enhancement of mechanical properties are highlighted. The developments in this area target effective cell growth, which is shown to be enhanced by the addition of colloidal particles.}},
  articleno    = {{125185}},
  author       = {{Abalymov, Anatolii and Parakhonskiy, Bogdan and Skirtach, Andre}},
  issn         = {{0927-7757}},
  journal      = {{COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS}},
  keywords     = {{Colloid and Surface Chemistry,Hydrogels,Mineralisation,Particles,Focal adhesion,Polymers,Hybrid,Colloids,Cells,Nanoparticles,Microparticles}},
  language     = {{eng}},
  pages        = {{11}},
  title        = {{Colloids-at-surfaces : physicochemical approaches for facilitating cell adhesion on hybrid hydrogels}},
  url          = {{http://dx.doi.org/10.1016/j.colsurfa.2020.125185}},
  volume       = {{603}},
  year         = {{2020}},
}

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