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Bidirectional cingulate-dependent danger information transfer across rats

(2019) PLOS BIOLOGY. 17(12).
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Abstract
Social transmission of freezing behavior has been conceived of as a one-way phenomenon in which an observer "catches" the fear of another. Here, we use a paradigm in which an observer rat witnesses another rat receiving electroshocks. Bayesian model comparison and Granger causality show that rats exchange information about danger in both directions: how the observer reacts to the demonstrator's distress also influences how the demonstrator responds to the danger. This was true to a similar extent across highly familiar and entirely unfamiliar rats but is stronger in animals preexposed to shocks. Injecting muscimol in the anterior cingulate of observers reduced freezing in the observers and in the demonstrators receiving the shocks. Using simulations, we support the notion that the coupling of freezing across rats could be selected for to more efficiently detect dangers in a group, in a way similar to cross-species eavesdropping.
Keywords
General Biochemistry, Genetics and Molecular Biology, General Immunology and Microbiology, General Neuroscience, General Agricultural and Biological Sciences, CONDITIONED FEAR RESPONSES, OBSERVATIONAL FEAR, EMOTIONAL CONTAGION, PAIN, EMPATHY, ACTIVATION, BEHAVIOR, STRESS, SYSTEM, NEUROSCIENCE

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Citation

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MLA
Han, Yingying, et al. “Bidirectional Cingulate-Dependent Danger Information Transfer across Rats.” PLOS BIOLOGY, edited by Frans B. M. de Waal, vol. 17, no. 12, 2019, doi:10.1371/journal.pbio.3000524.
APA
Han, Y., Bruls, R., Soyman, E., Thomas, R. M., Pentaraki, V., Jelinek, N., … Keysers, C. (2019). Bidirectional cingulate-dependent danger information transfer across rats. PLOS BIOLOGY, 17(12). https://doi.org/10.1371/journal.pbio.3000524
Chicago author-date
Han, Yingying, Rune Bruls, Efe Soyman, Rajat Mani Thomas, Vasiliki Pentaraki, Naomi Jelinek, Mirjam Heinemans, et al. 2019. “Bidirectional Cingulate-Dependent Danger Information Transfer across Rats.” Edited by Frans B. M. de Waal. PLOS BIOLOGY 17 (12). https://doi.org/10.1371/journal.pbio.3000524.
Chicago author-date (all authors)
Han, Yingying, Rune Bruls, Efe Soyman, Rajat Mani Thomas, Vasiliki Pentaraki, Naomi Jelinek, Mirjam Heinemans, Iege Bassez, Sam Verschooren, Illanah Pruis, Thijs Van Lierde, Nathaly Carrillo, Valeria Gazzola, Maria Carrillo, and Christian Keysers. 2019. “Bidirectional Cingulate-Dependent Danger Information Transfer across Rats.” Ed by. Frans B. M. de Waal. PLOS BIOLOGY 17 (12). doi:10.1371/journal.pbio.3000524.
Vancouver
1.
Han Y, Bruls R, Soyman E, Thomas RM, Pentaraki V, Jelinek N, et al. Bidirectional cingulate-dependent danger information transfer across rats. de Waal FBM, editor. PLOS BIOLOGY. 2019;17(12).
IEEE
[1]
Y. Han et al., “Bidirectional cingulate-dependent danger information transfer across rats,” PLOS BIOLOGY, vol. 17, no. 12, 2019.
@article{8663179,
  abstract     = {Social transmission of freezing behavior has been conceived of as a one-way phenomenon in which an observer "catches" the fear of another. Here, we use a paradigm in which an observer rat witnesses another rat receiving electroshocks. Bayesian model comparison and Granger causality show that rats exchange information about danger in both directions: how the observer reacts to the demonstrator's distress also influences how the demonstrator responds to the danger. This was true to a similar extent across highly familiar and entirely unfamiliar rats but is stronger in animals preexposed to shocks. Injecting muscimol in the anterior cingulate of observers reduced freezing in the observers and in the demonstrators receiving the shocks. Using simulations, we support the notion that the coupling of freezing across rats could be selected for to more efficiently detect dangers in a group, in a way similar to cross-species eavesdropping.},
  articleno    = {e3000524},
  author       = {Han, Yingying and Bruls, Rune and Soyman, Efe and Thomas, Rajat Mani and Pentaraki, Vasiliki and Jelinek, Naomi and Heinemans, Mirjam and Bassez, Iege and Verschooren, Sam and Pruis, Illanah and Van Lierde, Thijs and Carrillo, Nathaly and Gazzola, Valeria and Carrillo, Maria and Keysers, Christian},
  editor       = {de Waal, Frans B. M.},
  issn         = {1544-9173},
  journal      = {PLOS BIOLOGY},
  keywords     = {General Biochemistry,Genetics and Molecular Biology,General Immunology and Microbiology,General Neuroscience,General Agricultural and Biological Sciences,CONDITIONED FEAR RESPONSES,OBSERVATIONAL FEAR,EMOTIONAL CONTAGION,PAIN,EMPATHY,ACTIVATION,BEHAVIOR,STRESS,SYSTEM,NEUROSCIENCE},
  language     = {eng},
  number       = {12},
  pages        = {38},
  title        = {Bidirectional cingulate-dependent danger information transfer across rats},
  url          = {http://dx.doi.org/10.1371/journal.pbio.3000524},
  volume       = {17},
  year         = {2019},
}

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