@article{8658537,
  abstract     = {{Dynamic sequence-defined oligomers carrying a chemically written pin code are obtained through a strategy combining multicomponent reactions with the thermoreversible addition of 1,2,4-triazoline-3,5-diones (TADs) to indole substrates. The precision oligomers are specifically designed to be encrypted upon heating as a result of the random reshuffling of the TAD-indole covalent bonds within the backbone, thereby resulting in the scrambling of the encoded information. The encrypted pin code can eventually be decrypted following a second heating step that enables the macromolecular pin code to be deciphered using 1D electrospray ionization-mass spectrometry (ESI-MS). The herein introduced concept of encryption/decryption represents a key advancement compared with current strategies that typically use uncontrolled degradation to erase and tandem mass spectrometry (MS/MS) to analyze, decipher, and read-out chemically encrypted information. Additionally, the synthesized macromolecules are coated onto a high-value polymer material, which demonstrates their potential application as coded product tags for anti-counterfeiting purposes.}},
  articleno    = {{1903698}},
  author       = {{Holloway, Joshua and Van Lysebetten, Filip and Badi, Nezha and Houck, Hannes and Du Prez, Filip}},
  issn         = {{2198-3844}},
  journal      = {{ADVANCED SCIENCE}},
  keywords     = {{NEXT-GENERATION,STORAGE,INFORMATION,DESIGN,CLICK,1,2,4-triazoline-3,5-dione,chemical encryption,multicomponent,reactions,sequence-defined macromolecules}},
  language     = {{eng}},
  number       = {{8}},
  pages        = {{7}},
  title        = {{From sequence-defined macromolecules to macromolecular pin codes}},
  url          = {{http://dx.doi.org/10.1002/advs.201903698}},
  volume       = {{7}},
  year         = {{2020}},
}

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