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Change in grip strength in trans people and its association with lean body mass and bone density

(2019) ENDOCRINE CONNECTIONS. 8(7). p.1020-1028
Author
Organization
Abstract
Objective: Gender-affirming hormonal treatment (HT) in trans people changes physical appearance. Muscle mass and strength are important aspects of physical appearance, but few data exist on the effect of HT on grip strength and muscle mass. This study aimed to investigate the change in grip strength in trans people during the first year of HT and to study the possible determinants of this change and the associations between changes in grip strength, lean body mass and bone mineral density (BMD). Design and methods: A multicenter, prospective study was performed, including 249 transwomen and 278 transmen. Grip strength, lean body mass and BMD were measured at baseline and after 1 year. Results: After 1 year of HT, grip strength decreased with -1.8 kg (95% CI -2.6; -1.0) in transwomen and increased with +6.1 kg (95% CI +5.5; +6.7) in transmen. No differences in grip strength change was found between age groups, BMI groups, hormonal administration routes or hormone concentrations. In transmen, increase in grip strength was associated with increase in lean body mass (per kg increase in grip strength: +0.010 kg, 95% CI +0.003; +0.017), while this was not found in transwomen (per kg increase in grip strength: +0.004 kg, 95% CI -0.000; +0.009). Change in grip strength was not associated with change in BMD in transwomen and transmen. Conclusions: After 1 year of HT, grip strength decreased in transwomen, and increased in transmen. In transmen only, change in grip strength was associated with change in lean body mass.
Keywords
HORMONAL-THERAPY, EUROPEAN NETWORK, MINERAL DENSITY, TESTOSTERONE, MUSCLE, INCREASES, transgender, gender-affirming hormonal treatment, grip strength, muscle mass

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Citation

Please use this url to cite or link to this publication:

MLA
Scharff, Miranda, et al. “Change in Grip Strength in Trans People and Its Association with Lean Body Mass and Bone Density.” ENDOCRINE CONNECTIONS, vol. 8, no. 7, 2019, pp. 1020–28.
APA
Scharff, M., Wiepjes, C. M., Klaver, M., Schreiner, T., T’Sjoen, G., & den Heijer, M. (2019). Change in grip strength in trans people and its association with lean body mass and bone density. ENDOCRINE CONNECTIONS, 8(7), 1020–1028.
Chicago author-date
Scharff, Miranda, Chantal Maria Wiepjes, Maartje Klaver, Thomas Schreiner, Guy T’Sjoen, and Martin den Heijer. 2019. “Change in Grip Strength in Trans People and Its Association with Lean Body Mass and Bone Density.” ENDOCRINE CONNECTIONS 8 (7): 1020–28.
Chicago author-date (all authors)
Scharff, Miranda, Chantal Maria Wiepjes, Maartje Klaver, Thomas Schreiner, Guy T’Sjoen, and Martin den Heijer. 2019. “Change in Grip Strength in Trans People and Its Association with Lean Body Mass and Bone Density.” ENDOCRINE CONNECTIONS 8 (7): 1020–1028.
Vancouver
1.
Scharff M, Wiepjes CM, Klaver M, Schreiner T, T’Sjoen G, den Heijer M. Change in grip strength in trans people and its association with lean body mass and bone density. ENDOCRINE CONNECTIONS. 2019;8(7):1020–8.
IEEE
[1]
M. Scharff, C. M. Wiepjes, M. Klaver, T. Schreiner, G. T’Sjoen, and M. den Heijer, “Change in grip strength in trans people and its association with lean body mass and bone density,” ENDOCRINE CONNECTIONS, vol. 8, no. 7, pp. 1020–1028, 2019.
@article{8652749,
  abstract     = {Objective: Gender-affirming hormonal treatment (HT) in trans people changes physical appearance. Muscle mass and strength are important aspects of physical appearance, but few data exist on the effect of HT on grip strength and muscle mass. This study aimed to investigate the change in grip strength in trans people during the first year of HT and to study the possible determinants of this change and the associations between changes in grip strength, lean body mass and bone mineral density (BMD). Design and methods: A multicenter, prospective study was performed, including 249 transwomen and 278 transmen. Grip strength, lean body mass and BMD were measured at baseline and after 1 year. Results: After 1 year of HT, grip strength decreased with -1.8 kg (95% CI -2.6; -1.0) in transwomen and increased with +6.1 kg (95% CI +5.5; +6.7) in transmen. No differences in grip strength change was found between age groups, BMI groups, hormonal administration routes or hormone concentrations. In transmen, increase in grip strength was associated with increase in lean body mass (per kg increase in grip strength: +0.010 kg, 95% CI +0.003; +0.017), while this was not found in transwomen (per kg increase in grip strength: +0.004 kg, 95% CI -0.000; +0.009). Change in grip strength was not associated with change in BMD in transwomen and transmen. Conclusions: After 1 year of HT, grip strength decreased in transwomen, and increased in transmen. In transmen only, change in grip strength was associated with change in lean body mass.},
  author       = {Scharff, Miranda and Wiepjes, Chantal Maria and Klaver, Maartje and Schreiner, Thomas and T'Sjoen, Guy and den Heijer, Martin},
  issn         = {2049-3614},
  journal      = {ENDOCRINE CONNECTIONS},
  keywords     = {HORMONAL-THERAPY,EUROPEAN NETWORK,MINERAL DENSITY,TESTOSTERONE,MUSCLE,INCREASES,transgender,gender-affirming hormonal treatment,grip strength,muscle mass},
  language     = {eng},
  number       = {7},
  pages        = {1020--1028},
  title        = {Change in grip strength in trans people and its association with lean body mass and bone density},
  url          = {http://dx.doi.org/10.1530/EC-19-0196},
  volume       = {8},
  year         = {2019},
}

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