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Survey by TEDDY European Network of Excellence for Paediatric Clinical Research demonstrates potential for Europe‐wide trials

(2019) ACTA PAEDIATRICA. 109(3). p.607-612
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Abstract
Aim: The European Network of Excellence for Paediatric Clinical Research, known as the TEDDY Network, carried out a survey to determine the capacity and competence of paediatric centres to perform research studies. Methods: A cross-sectional, web-based pilot survey was conducted from October 2016 to April 2017 with paediatric clinical research centres in 11 countries: Albania, Austria, Belgium, Denmark, Iceland, Ireland, Italy, Norway, Spain, Switzerland and the United Kingdom. All were registered with the TEDDY Network database. Results: We approached 107 centres and 63 provided data on their experiences and expertise in paediatric clinical trials. Four groups of performance indicators were identified, referring to scientific experience, trial readiness, trial competence, regulatory issues, ethics and patients. Most centres were actively involved in paediatric clinical research: 53 centres (84.1%) had received funds for more than five paediatric studies in the last 5 years, and 42 (66.7%) had a specific clinical trial unit and dedicated study coordinators. We concluded that the European centres we studied had the capability and capacity to conduct paediatric trials, but there was still room for improvement, including enhanced collaboration. Conclusion: This pilot survey demonstrated that there is potential for performing paediatric trials across Europe, but improvements are possible.
Keywords
capacity, clinical research, competence, Europe, paediatric trials

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MLA
Ruggieri, Lucia, et al. “Survey by TEDDY European Network of Excellence for Paediatric Clinical Research Demonstrates Potential for Europe‐wide Trials.” ACTA PAEDIATRICA, vol. 109, no. 3, 2019, pp. 607–12.
APA
Ruggieri, L., Bonifazi, D., Landi, A., Bonifazi, F., Bartoloni, F., Costello, M., … Ceci, A. (2019). Survey by TEDDY European Network of Excellence for Paediatric Clinical Research demonstrates potential for Europe‐wide trials. ACTA PAEDIATRICA, 109(3), 607–612.
Chicago author-date
Ruggieri, Lucia, Donato Bonifazi, Annalisa Landi, Fedele Bonifazi, Franco Bartoloni, Mary Costello, Maria Grazia Felisi, et al. 2019. “Survey by TEDDY European Network of Excellence for Paediatric Clinical Research Demonstrates Potential for Europe‐wide Trials.” ACTA PAEDIATRICA 109 (3): 607–12.
Chicago author-date (all authors)
Ruggieri, Lucia, Donato Bonifazi, Annalisa Landi, Fedele Bonifazi, Franco Bartoloni, Mary Costello, Maria Grazia Felisi, Elke Gasthuys, Anila Godo, Federico Martinon Torres, David Nadal, Lieve Nuytinck, Francesca Rocchi, Mark Turner, and Adriana Ceci. 2019. “Survey by TEDDY European Network of Excellence for Paediatric Clinical Research Demonstrates Potential for Europe‐wide Trials.” ACTA PAEDIATRICA 109 (3): 607–612.
Vancouver
1.
Ruggieri L, Bonifazi D, Landi A, Bonifazi F, Bartoloni F, Costello M, et al. Survey by TEDDY European Network of Excellence for Paediatric Clinical Research demonstrates potential for Europe‐wide trials. ACTA PAEDIATRICA. 2019;109(3):607–12.
IEEE
[1]
L. Ruggieri et al., “Survey by TEDDY European Network of Excellence for Paediatric Clinical Research demonstrates potential for Europe‐wide trials,” ACTA PAEDIATRICA, vol. 109, no. 3, pp. 607–612, 2019.
@article{8651344,
  abstract     = {Aim: The European Network of Excellence for Paediatric Clinical Research, known as the TEDDY Network, carried out a survey to determine the capacity and competence of paediatric centres to perform research studies. 
Methods: A cross-sectional, web-based pilot survey was conducted from October 2016 to April 2017 with paediatric clinical research centres in 11 countries: Albania, Austria, Belgium, Denmark, Iceland, Ireland, Italy, Norway, Spain, Switzerland and the United Kingdom. All were registered with the TEDDY Network database. 
Results: We approached 107 centres and 63 provided data on their experiences and expertise in paediatric clinical trials. Four groups of performance indicators were identified, referring to scientific experience, trial readiness, trial competence, regulatory issues, ethics and patients. Most centres were actively involved in paediatric clinical research: 53 centres (84.1%) had received funds for more than five paediatric studies in the last 5 years, and 42 (66.7%) had a specific clinical trial unit and dedicated study coordinators. We concluded that the European centres we studied had the capability and capacity to conduct paediatric trials, but there was still room for improvement, including enhanced collaboration. 
Conclusion: This pilot survey demonstrated that there is potential for performing paediatric trials across Europe, but improvements are possible.},
  author       = {Ruggieri, Lucia and Bonifazi, Donato and Landi, Annalisa and Bonifazi, Fedele and Bartoloni, Franco and Costello, Mary and Felisi, Maria Grazia and Gasthuys, Elke and Godo, Anila and Martinon Torres, Federico and Nadal, David and Nuytinck, Lieve and Rocchi, Francesca and Turner, Mark and Ceci, Adriana},
  issn         = {0803-5253},
  journal      = {ACTA PAEDIATRICA},
  keywords     = {capacity,clinical research,competence,Europe,paediatric trials},
  language     = {eng},
  number       = {3},
  pages        = {607--612},
  title        = {Survey by TEDDY European Network of Excellence for Paediatric Clinical Research demonstrates potential for Europe‐wide trials},
  url          = {http://dx.doi.org/10.1111/apa.15020},
  volume       = {109},
  year         = {2019},
}

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