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Implementation of patient-tailored contrast volumes based on body surface area and heart rate harmonizes contrast enhancement and reduces contrast load in small patients in portal venous phase abdominal CT

M-S Walgraeve, L Pyfferoen, K Van De Moortele, F Zanca, D Bielen and Jan Casselman (UGent)
(2019) EUROPEAN JOURNAL OF RADIOLOGY. 121.
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Abstract
Purpose: The aim of this study was to evaluate the impact of a patient-tailored contrast volume protocol on portal venous phase abdominal CT-images compared to a fixed volume protocol in daily radiological practice. Method: Data of 77 patients who underwent two contrast-enhanced CT-examinations were collected. The first examination was performed with a fixed contrast volume (95 ml), the follow-up examination was performed with a patient-tailored contrast volume based on patient's BSA and heart rate. The patient-tailored volume was calculated by a software application integrated in the interface of the injection pump. Two independent radiologists assessed subjective and objective image quality. Differences in enhancement and contrast volumes between both protocols were analysed. Results: Despite a significant contrast volume reduction in women and in patients with low to normal BMI, enhancement was more consistent over different BMI-categories in the patient-tailored contrast volume protocol and there was no significant difference in subjective image quality between both injection protocols. Conclusions: A patient-tailored contrast volume protocol based on BSA and heart rate can be considered in daily radiological practice to decrease contrast volumes in women and in low to normal BMI patients and to achieve more consistent contrast enhancement across different BMI-categories in venous phase abdominal CT.
Keywords
WEIGHT, INJECTION, COST, MDCT, Contrast media, Multi-detector computed tomography, Personalised, medicine, Image quality, Abdominal imaging, Contrast injection protocols

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MLA
Walgraeve, M. S., et al. “Implementation of Patient-Tailored Contrast Volumes Based on Body Surface Area and Heart Rate Harmonizes Contrast Enhancement and Reduces Contrast Load in Small Patients in Portal Venous Phase Abdominal CT.” EUROPEAN JOURNAL OF RADIOLOGY, vol. 121, 2019, doi:10.1016/j.ejrad.2019.07.031.
APA
Walgraeve, M.-S., Pyfferoen, L., Van De Moortele, K., Zanca, F., Bielen, D., & Casselman, J. (2019). Implementation of patient-tailored contrast volumes based on body surface area and heart rate harmonizes contrast enhancement and reduces contrast load in small patients in portal venous phase abdominal CT. EUROPEAN JOURNAL OF RADIOLOGY, 121. https://doi.org/10.1016/j.ejrad.2019.07.031
Chicago author-date
Walgraeve, M-S, L Pyfferoen, K Van De Moortele, F Zanca, D Bielen, and Jan Casselman. 2019. “Implementation of Patient-Tailored Contrast Volumes Based on Body Surface Area and Heart Rate Harmonizes Contrast Enhancement and Reduces Contrast Load in Small Patients in Portal Venous Phase Abdominal CT.” EUROPEAN JOURNAL OF RADIOLOGY 121. https://doi.org/10.1016/j.ejrad.2019.07.031.
Chicago author-date (all authors)
Walgraeve, M-S, L Pyfferoen, K Van De Moortele, F Zanca, D Bielen, and Jan Casselman. 2019. “Implementation of Patient-Tailored Contrast Volumes Based on Body Surface Area and Heart Rate Harmonizes Contrast Enhancement and Reduces Contrast Load in Small Patients in Portal Venous Phase Abdominal CT.” EUROPEAN JOURNAL OF RADIOLOGY 121. doi:10.1016/j.ejrad.2019.07.031.
Vancouver
1.
Walgraeve M-S, Pyfferoen L, Van De Moortele K, Zanca F, Bielen D, Casselman J. Implementation of patient-tailored contrast volumes based on body surface area and heart rate harmonizes contrast enhancement and reduces contrast load in small patients in portal venous phase abdominal CT. EUROPEAN JOURNAL OF RADIOLOGY. 2019;121.
IEEE
[1]
M.-S. Walgraeve, L. Pyfferoen, K. Van De Moortele, F. Zanca, D. Bielen, and J. Casselman, “Implementation of patient-tailored contrast volumes based on body surface area and heart rate harmonizes contrast enhancement and reduces contrast load in small patients in portal venous phase abdominal CT,” EUROPEAN JOURNAL OF RADIOLOGY, vol. 121, 2019.
@article{8649600,
  abstract     = {{Purpose: The aim of this study was to evaluate the impact of a patient-tailored contrast volume protocol on portal venous phase abdominal CT-images compared to a fixed volume protocol in daily radiological practice. 
Method: Data of 77 patients who underwent two contrast-enhanced CT-examinations were collected. The first examination was performed with a fixed contrast volume (95 ml), the follow-up examination was performed with a patient-tailored contrast volume based on patient's BSA and heart rate. The patient-tailored volume was calculated by a software application integrated in the interface of the injection pump. Two independent radiologists assessed subjective and objective image quality. Differences in enhancement and contrast volumes between both protocols were analysed. 
Results: Despite a significant contrast volume reduction in women and in patients with low to normal BMI, enhancement was more consistent over different BMI-categories in the patient-tailored contrast volume protocol and there was no significant difference in subjective image quality between both injection protocols. 
Conclusions: A patient-tailored contrast volume protocol based on BSA and heart rate can be considered in daily radiological practice to decrease contrast volumes in women and in low to normal BMI patients and to achieve more consistent contrast enhancement across different BMI-categories in venous phase abdominal CT.}},
  articleno    = {{108630}},
  author       = {{Walgraeve, M-S and Pyfferoen, L and Van De Moortele, K and Zanca, F and Bielen, D and Casselman, Jan}},
  issn         = {{0720-048X}},
  journal      = {{EUROPEAN JOURNAL OF RADIOLOGY}},
  keywords     = {{WEIGHT,INJECTION,COST,MDCT,Contrast media,Multi-detector computed tomography,Personalised,medicine,Image quality,Abdominal imaging,Contrast injection protocols}},
  language     = {{eng}},
  pages        = {{9}},
  title        = {{Implementation of patient-tailored contrast volumes based on body surface area and heart rate harmonizes contrast enhancement and reduces contrast load in small patients in portal venous phase abdominal CT}},
  url          = {{http://doi.org/10.1016/j.ejrad.2019.07.031}},
  volume       = {{121}},
  year         = {{2019}},
}
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