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Proton magnetic resonance spectroscopy in skeletal muscle : experts' consensus recommendations

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Abstract
H-1-MR spectroscopy of skeletal muscle provides insight into metabolism that is not available noninvasively by other methods. The recommendations given in this article are intended to guide those who have basic experience in general MRS to the special application of H-1-MRS in skeletal muscle. The highly organized structure of skeletal muscle leads to effects that change spectral features far beyond simple peak heights, depending on the type and orientation of the muscle. Specific recommendations are given for the acquisition of three particular metabolites (intramyocellular lipids, carnosine and acetylcarnitine) and for preconditioning of experiments and instructions to study volunteers.
Keywords
acetylacarnitine, carnosine, deoxymyoglobine, intramyocellular lipids, lactate, magnetic resonance spectroscopy, physiology, skeletal muscle, BETA-ALANINE SUPPLEMENTATION, INTRAMYOCELLULAR LIPID-CONTENT, H-1 MR SPECTRA, IN-VIVO, INSULIN-RESISTANCE, NONINVASIVE ASSESSMENT, TRIGLYCERIDE CONTENT, EXERCISE INTENSITY, GLUCOSE-TOLERANCE, RELAXATION-TIMES

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MLA
Krššák, Martin, et al. “Proton Magnetic Resonance Spectroscopy in Skeletal Muscle : Experts’ Consensus Recommendations.” NMR IN BIOMEDICINE, vol. 34, no. 5, 2021, doi:10.1002/nbm.4266.
APA
Krššák, M., Lindeboom, L., Schrauwen‐Hinderling, V., Szczepaniak, L., Derave, W., Lundbom, J., … Boesch, C. (2021). Proton magnetic resonance spectroscopy in skeletal muscle : experts’ consensus recommendations. NMR IN BIOMEDICINE, 34(5). https://doi.org/10.1002/nbm.4266
Chicago author-date
Krššák, Martin, Lucas Lindeboom, Vera Schrauwen‐Hinderling, Lidia Szczepaniak, Wim Derave, Jesper Lundbom, Douglas Befroy, et al. 2021. “Proton Magnetic Resonance Spectroscopy in Skeletal Muscle : Experts’ Consensus Recommendations.” NMR IN BIOMEDICINE 34 (5). https://doi.org/10.1002/nbm.4266.
Chicago author-date (all authors)
Krššák, Martin, Lucas Lindeboom, Vera Schrauwen‐Hinderling, Lidia Szczepaniak, Wim Derave, Jesper Lundbom, Douglas Befroy, Fritz Schick, Jürgen Machann, Roland Kreis, and Chris Boesch. 2021. “Proton Magnetic Resonance Spectroscopy in Skeletal Muscle : Experts’ Consensus Recommendations.” NMR IN BIOMEDICINE 34 (5). doi:10.1002/nbm.4266.
Vancouver
1.
Krššák M, Lindeboom L, Schrauwen‐Hinderling V, Szczepaniak L, Derave W, Lundbom J, et al. Proton magnetic resonance spectroscopy in skeletal muscle : experts’ consensus recommendations. NMR IN BIOMEDICINE. 2021;34(5).
IEEE
[1]
M. Krššák et al., “Proton magnetic resonance spectroscopy in skeletal muscle : experts’ consensus recommendations,” NMR IN BIOMEDICINE, vol. 34, no. 5, 2021.
@article{8646306,
  abstract     = {{H-1-MR spectroscopy of skeletal muscle provides insight into metabolism that is not available noninvasively by other methods. The recommendations given in this article are intended to guide those who have basic experience in general MRS to the special application of H-1-MRS in skeletal muscle. The highly organized structure of skeletal muscle leads to effects that change spectral features far beyond simple peak heights, depending on the type and orientation of the muscle. Specific recommendations are given for the acquisition of three particular metabolites (intramyocellular lipids, carnosine and acetylcarnitine) and for preconditioning of experiments and instructions to study volunteers.}},
  articleno    = {{e4266}},
  author       = {{Krššák, Martin and Lindeboom, Lucas and Schrauwen‐Hinderling, Vera and Szczepaniak, Lidia and Derave, Wim and Lundbom, Jesper and Befroy, Douglas and Schick, Fritz and Machann, Jürgen and Kreis, Roland and Boesch, Chris}},
  issn         = {{0952-3480}},
  journal      = {{NMR IN BIOMEDICINE}},
  keywords     = {{acetylacarnitine,carnosine,deoxymyoglobine,intramyocellular lipids,lactate,magnetic resonance spectroscopy,physiology,skeletal muscle,BETA-ALANINE SUPPLEMENTATION,INTRAMYOCELLULAR LIPID-CONTENT,H-1 MR SPECTRA,IN-VIVO,INSULIN-RESISTANCE,NONINVASIVE ASSESSMENT,TRIGLYCERIDE CONTENT,EXERCISE INTENSITY,GLUCOSE-TOLERANCE,RELAXATION-TIMES}},
  language     = {{eng}},
  number       = {{5}},
  pages        = {{20}},
  title        = {{Proton magnetic resonance spectroscopy in skeletal muscle : experts' consensus recommendations}},
  url          = {{http://dx.doi.org/10.1002/nbm.4266}},
  volume       = {{34}},
  year         = {{2021}},
}

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