Immune-mediated hemolytic anemia associated with chronic fibrosing mediastinitis in an Arabo-Friesian horse
- Author
- Caroline Ribonnet, Veronique Saey (UGent) , Richard Ducatelle (UGent) and Katrien Palmers (UGent)
- Organization
- Abstract
- In this report, a ten-year-old gelding with immune-mediated hemolytic anemia associated with chronic fibrosing mediastinitis of unknown origin is described. The patient suffered from chronic weight loss and intermittent diarrhea for already several months. He was presented with severe anemia, anorexia and fever of a 24-hour onset. A direct Coombs test was highly positive for IgG auto-agglutination. No evidence of an underlying process was found on clinical examination. Post-mortem examination revealed green liquid material containing food particles in the cranial mediastinum and histology suggested chronic fibrosing mediastinitis. Even though perforation of the esophagus is a plausible cause, no signs of esophageal rupture were noted on macroscopic examination. This case shows that non-responsive, immune-mediated hemolytic anemia can be due to an undetected underlying disease, such as chronic mediastinitis.
- In deze casuïstiek wordt een tienjarige ruin beschreven met immuungemedieerde hemolytische anemie geassocieerd met chronische fibroserende mediastinitis van onbekende oorsprong. De patiënt leed aan chronisch gewichtsverlies en intermitterende diarree en werd aangeboden in de kliniek met uitgesproken anemie, anorexie en koorts die reeds 24 uur aanwezig was. Een directe Coombs’ test was sterk positief voor IgG-autoagglutinatie. Bij het klinisch onderzoek werd geen onderliggend patho- logisch proces van de immuungemedieerde hemolytische anemie gevonden. Post-mortemonderzoek toonde groene vloeistof met voedselpartikels in het craniale mediastinum aan. Histologisch onderzoek suggereerde chronische fibroserende mediastinitis. Hoewel slokdarmperforatie hiervoor een mogeli - jke oorzaak is, werden bij macroscopisch onderzoek geen tekenen van ruptuur waargenomen. In deze casereport wordt aangetoond dat bij niet-responsieve, immuungemedieerde hemolytische anemie, een niet-gedetecteerde onderliggende pathologie, zoals chronische mediastinitis, aanwezig kan zijn.
- Keywords
- DESCENDING NECROTIZING MEDIASTINITIS, IDIOPATHIC MUSCULAR HYPERTROPHY, PENICILLIN, ABSCESS, PLEURITIS, SECONDARY, COMPLICATION, PERFORATION, FEATURES, PATIENT
Downloads
-
(...).pdf
- full text (Published version)
- |
- UGent only
- |
- |
- 731.28 KB
Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-8645154
- MLA
- Ribonnet, Caroline, et al. “Immune-Mediated Hemolytic Anemia Associated with Chronic Fibrosing Mediastinitis in an Arabo-Friesian Horse.” VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT, vol. 88, no. 5, Univ Ghent, 2019, pp. 278–85.
- APA
- Ribonnet, C., Saey, V., Ducatelle, R., & Palmers, K. (2019). Immune-mediated hemolytic anemia associated with chronic fibrosing mediastinitis in an Arabo-Friesian horse. VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT, 88(5), 278–285.
- Chicago author-date
- Ribonnet, Caroline, Veronique Saey, Richard Ducatelle, and Katrien Palmers. 2019. “Immune-Mediated Hemolytic Anemia Associated with Chronic Fibrosing Mediastinitis in an Arabo-Friesian Horse.” VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT 88 (5): 278–85.
- Chicago author-date (all authors)
- Ribonnet, Caroline, Veronique Saey, Richard Ducatelle, and Katrien Palmers. 2019. “Immune-Mediated Hemolytic Anemia Associated with Chronic Fibrosing Mediastinitis in an Arabo-Friesian Horse.” VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT 88 (5): 278–285.
- Vancouver
- 1.Ribonnet C, Saey V, Ducatelle R, Palmers K. Immune-mediated hemolytic anemia associated with chronic fibrosing mediastinitis in an Arabo-Friesian horse. VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT. 2019;88(5):278–85.
- IEEE
- [1]C. Ribonnet, V. Saey, R. Ducatelle, and K. Palmers, “Immune-mediated hemolytic anemia associated with chronic fibrosing mediastinitis in an Arabo-Friesian horse,” VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT, vol. 88, no. 5, pp. 278–285, 2019.
@article{8645154,
abstract = {{In this report, a ten-year-old gelding with immune-mediated hemolytic anemia associated with chronic fibrosing mediastinitis of unknown origin is described. The patient suffered from chronic weight loss and intermittent diarrhea for already several months. He was presented with severe anemia, anorexia and fever of a 24-hour onset. A direct Coombs test was highly positive for IgG auto-agglutination. No evidence of an underlying process was found on clinical examination. Post-mortem examination revealed green liquid material containing food particles in the cranial mediastinum and histology suggested chronic fibrosing mediastinitis. Even though perforation of the esophagus is a plausible cause, no signs of esophageal rupture were noted on macroscopic examination. This case shows that non-responsive, immune-mediated hemolytic anemia can be due to an undetected underlying disease, such as chronic mediastinitis.}},
author = {{Ribonnet, Caroline and Saey, Veronique and Ducatelle, Richard and Palmers, Katrien}},
issn = {{0303-9021}},
journal = {{VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT}},
keywords = {{DESCENDING NECROTIZING MEDIASTINITIS,IDIOPATHIC MUSCULAR HYPERTROPHY,PENICILLIN,ABSCESS,PLEURITIS,SECONDARY,COMPLICATION,PERFORATION,FEATURES,PATIENT}},
language = {{eng}},
number = {{5}},
pages = {{278--285}},
publisher = {{Univ Ghent}},
title = {{Immune-mediated hemolytic anemia associated with chronic fibrosing mediastinitis in an Arabo-Friesian horse}},
volume = {{88}},
year = {{2019}},
}