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Subthalamic nucleus activity in the processing of body and mental action verbs in people with Parkinson’s disease

Miet De Letter (UGent) , Arnout Bruggeman (UGent) , Kim De Keyser (UGent) , Pieter van Mierlo (UGent) , Heidi Buysse (UGent) , Dirk Van Roost (UGent) and Patrick Santens (UGent)
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Abstract
Local field potentials evoked by body action and mental action verbs were recorded in the subthalamic nucleus (STN) of 18 patients with Parkinson's disease through the electrodes implanted for deep brain stimulation. Compared with the medication on-condition, the medication off-condition showed a difference in activity in the early time segments, mainly in the right STN, with larger amplitudes for body action verbs. In the on-condition a similar pattern was detected in the left STN. These patterns of early differences in activity evoked by different types of verbs might indicate the potential of the STN to rapidly detect relevant behavioural clues in verbal content and to integrate these in subsequent cortico-subcortical interactions. In addition, these lateralizations allow speculations about shifts in processing activity correlating with dopaminergic denervation. Whether this detection relies on phonological, semantic or grammatical clues remains an open question.
Keywords
Local field potentials, Action verbs, Embodiment, Language, Semantics, Phonology, Grammatics, Parkinson, Subthalamic nucleus, NONDEMENTED PATIENTS, ACTION WORDS, LANGUAGE, BRAIN, MOTOR, STIMULATION, GENERATION, REPRESENTATION, SEMANTICS, FREQUENCY

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MLA
De Letter, Miet, et al. “Subthalamic Nucleus Activity in the Processing of Body and Mental Action Verbs in People with Parkinson’s Disease.” BRAIN AND LANGUAGE, vol. 202, 2020.
APA
De Letter, M., Bruggeman, A., De Keyser, K., van Mierlo, P., Buysse, H., Van Roost, D., & Santens, P. (2020). Subthalamic nucleus activity in the processing of body and mental action verbs in people with Parkinson’s disease. BRAIN AND LANGUAGE, 202.
Chicago author-date
De Letter, Miet, Arnout Bruggeman, Kim De Keyser, Pieter van Mierlo, Heidi Buysse, Dirk Van Roost, and Patrick Santens. 2020. “Subthalamic Nucleus Activity in the Processing of Body and Mental Action Verbs in People with Parkinson’s Disease.” BRAIN AND LANGUAGE 202.
Chicago author-date (all authors)
De Letter, Miet, Arnout Bruggeman, Kim De Keyser, Pieter van Mierlo, Heidi Buysse, Dirk Van Roost, and Patrick Santens. 2020. “Subthalamic Nucleus Activity in the Processing of Body and Mental Action Verbs in People with Parkinson’s Disease.” BRAIN AND LANGUAGE 202.
Vancouver
1.
De Letter M, Bruggeman A, De Keyser K, van Mierlo P, Buysse H, Van Roost D, et al. Subthalamic nucleus activity in the processing of body and mental action verbs in people with Parkinson’s disease. BRAIN AND LANGUAGE. 2020;202.
IEEE
[1]
M. De Letter et al., “Subthalamic nucleus activity in the processing of body and mental action verbs in people with Parkinson’s disease,” BRAIN AND LANGUAGE, vol. 202, 2020.
@article{8644210,
  abstract     = {Local field potentials evoked by body action and mental action verbs were recorded in the subthalamic nucleus (STN) of 18 patients with Parkinson's disease through the electrodes implanted for deep brain stimulation. Compared with the medication on-condition, the medication off-condition showed a difference in activity in the early time segments, mainly in the right STN, with larger amplitudes for body action verbs. In the on-condition a similar pattern was detected in the left STN. These patterns of early differences in activity evoked by different types of verbs might indicate the potential of the STN to rapidly detect relevant behavioural clues in verbal content and to integrate these in subsequent cortico-subcortical interactions. In addition, these lateralizations allow speculations about shifts in processing activity correlating with dopaminergic denervation. Whether this detection relies on phonological, semantic or grammatical clues remains an open question.},
  articleno    = {104738},
  author       = {De Letter, Miet and Bruggeman, Arnout and De Keyser, Kim and van Mierlo, Pieter and Buysse, Heidi and Van Roost, Dirk and Santens, Patrick},
  issn         = {0093-934X},
  journal      = {BRAIN AND LANGUAGE},
  keywords     = {Local field potentials,Action verbs,Embodiment,Language,Semantics,Phonology,Grammatics,Parkinson,Subthalamic nucleus,NONDEMENTED PATIENTS,ACTION WORDS,LANGUAGE,BRAIN,MOTOR,STIMULATION,GENERATION,REPRESENTATION,SEMANTICS,FREQUENCY},
  language     = {eng},
  pages        = {7},
  title        = {Subthalamic nucleus activity in the processing of body and mental action verbs in people with Parkinson’s disease},
  url          = {http://dx.doi.org/10.1016/j.bandl.2019.104738},
  volume       = {202},
  year         = {2020},
}

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